Catalog No.
PVV01801
Species reactivity
SARS-CoV-2 (2019-nCoV)
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant SARS-CoV-2 NSP13 (Ala5325-Gln5925).
Tested applications
ELISA: 1:4000-1:8000, WB: 1:2000-1:8000
Target
Helicase,Hel,Non-structural protein 13,nsp13,Replicase polyprotein 1ab,pp1ab,ORF1ab polyprotein
Purification
Purified by antigen affinity column.
Accession
P0DTD1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Mechanistic insights into bismuth(iii) inhibition of SARS-CoV-2 helicase., PMID:38966375
Heterotypic immunity from prior SARS-CoV-2 infection but not COVID-19 vaccination associates with lower endemic coronavirus incidence., PMID:38865483
Heterotypic responses against nsp12/nsp13 from prior SARS-CoV-2 infection associates with lower subsequent endemic coronavirus incidence., PMID:37961343
Porcine Epidemic Diarrhea Virus nsp13 Protein Downregulates Neonatal Fc Receptor Expression by Causing Promoter Hypermethylation through the NF-κB Signaling Pathway., PMID:36602596
Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19., PMID:35738278
Expression Profile and Localization of SARS-CoV-2 Nonstructural Replicase Proteins in Infected Cells., PMID:35730969
A Simplified SARS-CoV-2 Mouse Model Demonstrates Protection by an Oral Replicon-Based mRNA Vaccine., PMID:35250985
Bacteria-enabled oral delivery of a replicon-based mRNA vaccine candidate protects against ancestral and delta variant SARS-CoV-2., PMID:35123065
Highly feasible immunoprotective multicistronic SARS-CoV-2 vaccine candidate blending novel eukaryotic expression and Salmonella bactofection., PMID:35116175
RNAi-mediated siRNA sequences to combat the COVID-19 pandemic with the inhibition of SARS-CoV2., PMID:35071824
The impact of spike N501Y mutation on neutralizing activity and RBD binding of SARS-CoV-2 convalescent serum., PMID:34419925
Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients., PMID:33516277
Monoclonal Antibody: 5A9, 5C7, and 5G7 Against Porcine Epidemic Diarrhea Virus nsp13., PMID:33351713
Generation and Characterization of Monoclonal Antibody Against Porcine Epidemic Diarrhea Virus Nonstructural Protein 13., PMID:33351712
Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome., PMID:17520018
Identification and characterization of severe acute respiratory syndrome coronavirus replicase proteins., PMID:15331731