Catalog No.
PVV01701
Species reactivity
SARS-CoV-2 (2019-nCoV)
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant SARS-CoV-2 NSP12/RdRp (Asp4891-Val5212).
Tested applications
ELISA: 1:4000-1:8000, WB: 1:500-1:4000
Target
RNA-directed RNA polymerase,Pol,RdRp,Non-structural protein 12,nsp12,Replicase polyprotein 1ab,pp1ab,ORF1ab polyprotein
Concentration
0.3 mg/ml
Purification
Purified by antigen affinity column.
Accession
P0DTD1
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Single-B-cell cloning and recombinant antibodies generation to analyze the antigenicity of porcine reproductive and respiratory syndrome virus nonstructural protein 12., PMID:40203677
Clinical and molecular landscape of prolonged SARS-CoV-2 infection with resistance to remdesivir in immunocompromised patients., PMID:40160532
Investigation of Immunoreactivity Profiles and Epitope Landscape in Divergent COVID-19 Trajectories and SARS-CoV-2 Variants., PMID:39873496
Identification of new antigenic epitopes of porcine reproductive and respiratory syndrome virus nsp12 protein using monoclonal antibodies., PMID:39542336
MDA5 Is a Major Determinant of Developing Symptoms in Critically Ill COVID-19 Patients., PMID:39460899
Emergence of transmissible SARS-CoV-2 variants with decreased sensitivity to antivirals in immunocompromised patients with persistent infections., PMID:39294134
Identification of Immunodominant Epitopes of Dengue Virus 2 Envelope and NS1 Proteins: Evaluating the Diagnostic Potential of a Synthetic Peptide., PMID:38980575
Mechanistic insights into bismuth(iii) inhibition of SARS-CoV-2 helicase., PMID:38966375
Emergence and fixation of SARS-CoV-2 minority variants in a chronically infected patient receiving therapy in Denmark., PMID:38961316
Emergence of transmissible SARS-CoV-2 variants with decreased sensitivity to antivirals in immunocompromised patients with persistent infections., PMID:38946967
Heterotypic immunity from prior SARS-CoV-2 infection but not COVID-19 vaccination associates with lower endemic coronavirus incidence., PMID:38865483
Visualization of Early RNA Replication Kinetics of SARS-CoV-2 by Using Single Molecule RNA-FISH Combined with Immunofluorescence., PMID:38400039
Heterotypic responses against nsp12/nsp13 from prior SARS-CoV-2 infection associates with lower subsequent endemic coronavirus incidence., PMID:37961343
Clinical experience of treatment of immunocompromised individuals with persistent SARS-CoV-2 infection based on drug resistance mutations determined by genomic analysis: a descriptive study., PMID:37946111
Inside-out: Antibody-binding reveals potential folding hinge-points within the SARS-CoV-2 replication co-factor nsp9., PMID:37036856
Computational design of candidate multi-epitope vaccine against SARS-CoV-2 targeting structural (S and N) and non-structural (NSP3 and NSP12) proteins., PMID:36744449
Targeting viral proteins for restraining SARS-CoV-2: focusing lens on viral proteins beyond spike for discovering new drug targets., PMID:36723288
Development of novel monoclonal antibodies against nsp12 of SARS-CoV-2., PMID:36496472
Development and characterization of a new monoclonal antibody against SARS-CoV-2 NSP12 (RdRp)., PMID:36271490
Antiviral Drug Discovery for the Treatment of COVID-19 Infections., PMID:35632703
Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants., PMID:35532238
Development of Monoclonal Antibodies to Detect for SARS-CoV-2 Proteins., PMID:35405107
De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report., PMID:35301314
RNAi-mediated siRNA sequences to combat the COVID-19 pandemic with the inhibition of SARS-CoV2., PMID:35071824
SARS-CoV-2 immune repertoire in MIS-C and pediatric COVID-19., PMID:34611361
Serological and viral genetic features of patients with COVID-19 in a selected German patient cohort-correlation with disease characteristics., PMID:34468954
Potential transmission chains of variant B.1.1.7 and co-mutations of SARS-CoV-2., PMID:34127650
Molecular Architecture of Early Dissemination and Massive Second Wave of the SARS-CoV-2 Virus in a Major Metropolitan Area., PMID:33127862
An Overview of the Crystallized Structures of the SARS-CoV-2., PMID:33098476
Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches., PMID:33082015
Systematic review with meta-analysis of the accuracy of diagnostic tests for COVID-19., PMID:32659413
The genetic sequence, origin, and diagnosis of SARS-CoV-2., PMID:32333222
Development of Monoclonal Antibodies Specifically Recognizing the Nonstructural Protein 12 of Type 2 Porcine Reproductive and Respiratory Syndrome Virus., PMID:29708867
Identification of a linear B-cell epitope on non-structural protein 12 of porcine reproductive and respiratory syndrome virus, using a monoclonal antibody., PMID:28365807
Characterization of equine humoral antibody response to the nonstructural proteins of equine arteritis virus., PMID:21147938
Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome., PMID:17520018
Identification and characterization of severe acute respiratory syndrome coronavirus replicase proteins., PMID:15331731
For research use only. Not for human or drug use.
