Catalog No.
YHJ55102
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp275
Predicted molecular weight
36.55 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H1Y0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
APG5-like, Apoptosis-specific protein, ASP, APG5L, ATG5, Autophagy protein 5
Dysregulation of Host Histone Acetylation by Acinetobacter baumannii: A Novel Mechanism for Autophagy Inhibition and Bacterial Survival., PMID:40509567
Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway., PMID:40487763
Establishment of a Human Induced Pluripotent Stem Cell-Derived Cerebral Cortex Organoid Model for Neurotoxicity Assessment., PMID:40485229
CD46 TREM1 regulates the autophagy marker LC3B ATG5 in oral squamous cell carcinoma., PMID:40475017
[Regulation of apoptosis and autophagy in hepatoblastoma cells by Ganoderma lucidum polysaccharides through Akt/mTOR pathway]., PMID:40461199
The TECPR1:ATG5-ATG12 complex conjugates LC3/ATG8 to damaged lysosomes that expose luminal glycans in response to osmotic imbalance., PMID:40458442
ATG5 negatively regulates grass carp reovirus-induced immune-inflammatory response by degrading RIG-I and MDA5., PMID:40454785
MSC-Derived Exosomal MiR-127-3p Alleviates Acute Kidney Ischemia-Reperfusion Injury via Suppressing ATG5/ATG7-Mediated Autophagy., PMID:40452255
Activation of Sig-1R by afobazole attenuates Tollip/HMGB1-mediaded CCN2 autophagic degradation and NETs formation in sunitinib-induced cardiotoxicity in mice: Involvement of IRE 1α/ASK1/JNK/ AP-1 trajectory., PMID:40449751
A synthetic chlorophagy receptor promotes plant fitness by mediating chloroplast microautophagy., PMID:40448996
DSK2-mediated degradation of F-box protein LAO1 and class I TCPs modulates the nitrogen starvation response., PMID:40447910
Effects of Intermittent Fasting on Liver Steatosis and Fibrosis, Serum FGF-21 and Autophagy Markers in Metabolic Dysfunction-Associated Fatty Liver Disease: A Randomized Controlled Trial., PMID:40430125
ATG5 controls CD80 expression in B cells and shapes cognate CD4+ T cell responses., PMID:40426021
Cadmium-induced disruption of exosomal secretion and cellular pathways in leydig cells., PMID:40425944
CS-6-induced p62 accumulation exacerbates DNA damage in colorectal cancer., PMID:40417224
Spermine Enhances Cholesterol Effluence of Macrophages Through Caspase 2-Mediated Autophagy., PMID:40415363
Oscillatory shear stress activates integrin β3, blocking autophagic flux in endothelial cells and promoting endothelial cells senescence., PMID:40412535
Brevilin A, a novel BNIP3 inhibitor suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss via impairing mitophagy and mitochondrial metabolism., PMID:40408943
Therapeutic potential of fisetin in hepatic steatosis: Insights into autophagy pathway regulation and endoplasmic reticulum stress alleviation in high-fat diet-fed mice., PMID:40402993
Identification of a novel mechanism for regulation of the early autophagy machinery assembly by PKA., PMID:40395985
ATG5 is dispensable for ATG8ylation of cellular proteins., PMID:40395522
Antioxidant and anti-aging effect of queen bee larvae (Apis mellifera) protein hydrolysates in Drosophila melanogaster., PMID:40383333
Ammonia-induced testicular tissue damage: Apoptosis and autophagy pathways mediated by regulating Cyt C/Bcl-2 and p62/LC3B pathways., PMID:40381750
ATG5 suppresses type I IFN-dependent neutrophil effector functions during Mycobacterium tuberculosis infection in mice., PMID:40374743
[Effects of electroacupuncture at changbing fang on autophagy of colonic cells and gut microbiota in ulcerative colitis of rats]., PMID:40369923
Discovery of Golgi Membrane-associated Degradation Pathway, GOMED: A Focus on 15 Years of Ultrastructural Analyses., PMID:40358620
Endoplasmic reticulum stress regulates swainsonine-induced the autophagy in renal tubular epithelial cells through UPR signaling pathway., PMID:40354703
[Mechanism of BNIP3-mediated mitophagy in m.3635G>A related Leber hereditary optic neuropathy]., PMID:40350399
Proteostasis and autophagy disruption by the aging-related VGVAPG hexapeptide - preliminary insights into a potential novel elastin-induced neurodegeneration pathway in an in vitro human cellular neuron model., PMID:40348194
Estrogen promotes autophagy in the mammary epithelial cells of dairy sheep via the CXCL12/CXCR4 axis., PMID:40341494
SFTSV induces liver ferroptosis through m6A-related ferritinophagy., PMID:40340535
Inhibition of ATG5-mediated autophagy maintains PMAIP1 stability to promote cell apoptosis and suppress triple-negative breast cancer progression., PMID:40338396
Exploring the therapeutic potential of 4,4'-dimethoxychalcone: Inducing apoptosis in cancer cells via ER stress and autophagy disruption., PMID:40334804
TJ0113-induced mitophagy in acute liver failure detected by Raman microspectroscopy., PMID:40318303
The assembly of RAB22A/TMEM33/RTN4 initiates a secretory ER-phagy pathway., PMID:40301304
Kumatakenin alleviates depressive-like behaviors by suppressing excessive autophagy in hippocampus via ATG5., PMID:40294778
Progranulin enhances M2 macrophage polarization and renal fibrosis by modulating autophagy in chronic kidney disease., PMID:40293508
P2X7 Receptor Facilitates Cardiomyocyte Autophagy After Myocardial Infarction via Nox4/PERK/ATF4 Signaling Pathway., PMID:40289672
Investigating the Mechanisms of Esketamine in Treating Propofol-Induced Cognitive Impairment in Elderly Rats., PMID:40287805
The role of the ferroptosis pathway in the toxic mechanism of TCDD-induced liver damage in zebrafish., PMID:40286831
Qishen Huoxue Granule Ameliorates LPS-induced Cardiomyocyte Injury by Suppressing Excessive Autophagy via MasR/PI3K-AKT-mTOR Pathway., PMID:40277111
Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation., PMID:40274816
Inhibition of autophagy in the amygdala ameliorates anxiety-like behaviors induced by morphine-protracted withdrawal in male mice., PMID:40269606
Neuronal autophagy controls excitability via ryanodine receptor-mediated regulation of calcium-activated potassium channel function., PMID:40267139
[Effect of electroacupuncture of "Jiaji"(EX-B2) on autophagy and apoptosis of nucleus pulposus cells in degenerative intervertebral disc rabbits based on PI3K/AKT/mTOR pathway]., PMID:40262939
Buyang Huanwu decoction facilitates the repair of red nucleus neurons subsequent to spinal cord injury in rats via autophagy., PMID:40260978
Optimized Effects of Fisetin and Hydroxychloroquine on ER Stress and Autophagy in Nonalcoholic Fatty Pancreas Disease in Mice., PMID:40260275
Pathogenetic Involvement of Autophagy and Mitophagy in Primary Progressive Multiple Sclerosis., PMID:40257374
TJ0113 attenuates fibrosis in metabolic dysfunction-associated steatohepatitis by inducing mitophagy., PMID:40252468
Exploring the impact of Gastrodin on brain aging in mice: Unraveling mechanisms through network pharmacology., PMID:40250323
For research use only. Not for human or drug use.
