Catalog No.
YHC45401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr1021-Thr1330
Predicted molecular weight
35.61 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P0C0L5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CO4, Basic complement C4, Complement C4-B, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3, C4B, CPAMD3
Increased Complement C4 in a Sparse Neuronal Subset Induces Network-Wide Transcriptomic Alterations in the Prefrontal Cortex., PMID:40502190
[Correlation between complement deposition levels on blood cells and clinical biomarkers in patients with paroxysmal nocturnal hemoglobinuria]., PMID:40425452
Diverse cell types establish a pathogenic immune environment in peripheral neuropathy., PMID:40410792
Echinococcus multilocularis Calreticulin Inhibits Lectin Pathway of Complement Activation by Directly Binding to Mannose-Binding Lectin., PMID:40333123
A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion., PMID:40327719
Proteomic and In Silico Analyses Highlight Complement System's Role in Bladder Cancer Immune Regulation., PMID:40283026
Long-term GABA supplementation mitigates anxiety by modulating complement and neuroinflammatory pathways., PMID:40274802
Identification of serum C4BPA as a potential diagnostic marker of right ventricular remodelling via proteomic analysis., PMID:40237358
Proteomic Profiling of Age-Related Proteins Following Extracorporeal Apheresis., PMID:40233791
Genetically druggable targets for MAPK-activated colorectal cancer by a two-sample mendelian randomization analysis., PMID:40210889
The role of C4d expression in the diagnosis of bullous pemphigoid: a clinical and histopathological study., PMID:40095080
Multi-centered clinical validation demonstrating superior precision in lupus diagnosis: T cell autoantibodies and TC4d outperform conventional lupus erythematosus biomarkers., PMID:40093011
Decreased complement 4 and interleukin-10 as biomarkers in aqueous humour for non-exudative age-related macular degeneration: a case control study., PMID:40075380
Association of C4d with disease activity in anti-neutrophil cytoplasmic antibody-associated vasculitis: evidence for classical/lectin complement pathway activation., PMID:40045390
The prognostic relevance of donor-specific antibodies in facial transplantation - A retrospective cohort study., PMID:40043533
Clinical usefulness of E4-phytohemagglutinin reactive C4-binding protein relative front value in serum for distinguishing between ovarian clear cell adenocarcinoma and endometrioma., PMID:40024277
Spatial transcriptomics of Glomerulo-centric antibody mediated rejection in renal transplants., PMID:39993695
Human nasal turbinate stem cells with specific gene signatures (HAS2, CXCL1, KRTAP1-5, GSTT2B, and C4B) attenuate rheumatoid arthritis., PMID:39987230
Impact of Immunosuppressive Drug Concentrations on Microvascular Inflammation, Negative Donor-Specific Antibodies, and C4d-Negative Status in Kidney Transplant Recipients., PMID:39980440
Identification of multiple novel procoagulant plasma ligands for stabilin-2., PMID:39970990
Integrative Multi-omics Analysis and Mendelian Randomization Reveal Potential Therapeutic Targets and their Stratification in Lung Squamous Cell Carcinoma., PMID:39936431
Drug-resistant epilepsy associated with peripheral complement decreases and sex-specific cytokine imbalances: a pilot study., PMID:39934240
Granzyme K activates the entire complement cascade., PMID:39914456
Dynamic Complement Protein Changes in Aqueous Humor and Plasma of Patients With Retinal Vein Occlusion During Ranibizumab Treatment., PMID:39906134
Repurposing FDA-Approved Drugs Against Potential Drug Targets Involved in Brain Inflammation Contributing to Alzheimer's Disease., PMID:39897171
Plasma proteome fingerprint in kidney diseases., PMID:39896931
[Berberine ameliorates coronary artery endothelial cell injury in Kawasaki disease through complement and coagulation cascades]., PMID:39825659
Association of C4 Null Alleles and Persistently Low C4 in Asian Indian Patients With Systemic Lupus Erythematosus., PMID:39800843
Changes in Serum Proteins in Cats with Obesity: A Proteomic Approach., PMID:39795034
Molecular interaction profiling and binding dynamics of Cinnamomum zeylanicum phytochemicals with human pancreatic amylase., PMID:39761621
Effectiveness of complement inhibitors against refractory antibody-mediated rejection of lung transplantation: Two clinical cases., PMID:39756547
C4d immunostaining facilitates differentiation of pemphigoid nodularis from prurigo nodularis., PMID:39755047
Shedding light on the role of complement C4 activation in cancer., PMID:39732132
Proteomic signatures of Alzheimer's disease and Lewy body dementias: A comparative analysis., PMID:39711511
A Review of the Knops Blood Group System., PMID:39706812
iTRAQ proteomic analysis of exosomes derived from synovial fluid reveals disease patterns and potential biomarkers of Osteoarthritis., PMID:39702169
Survival of Borrelia burgdorferi Strain B31 in Human Serum Is Not Dependent on C4BP Binding to the Bacterial Surface., PMID:39599529
Insights into Medication-Induced Osteonecrosis of the Jaw Through the Application of Salivary Proteomics and Bioinformatics., PMID:39596473
Early and late antibody mediated rejection: Which game is the complement playing?, PMID:39591699
Intraocular complement activation is independent of systemic complement activation and is related to macular vascular remodelling in retinal vein occlusion., PMID:39587546
Biophysical characterization and structural insights of leptospiral complement regulator-acquiring protein A., PMID:39556937
C4b-Binding Protein and Factor H Attenuate NLRP3 Inflammasome-Mediated Signalling Response during Group A Streptococci Infection in Human Cells., PMID:39496236
Intraperitoneal MASP-1 Levels are Associated with Peritoneal Solute Transport Rate in Peritoneal Dialysis Patients: A Retrospective Cohort Study., PMID:39494204
A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion., PMID:39484374
Accurate Visualization of C4d Complement Fragment in Immunohistochemistry by C-Terminal Linear Neoepitope-Specific Antibodies., PMID:39408855
TMT-proteomics reveals the therapeutic effects of Lianling decoction against atopic dermatitis through Staphylococcus aureus infection., PMID:39403467
Alzheimer's disease clinical variants show distinct neuroinflammatory profiles with neuropathology., PMID:39400356
The role of S-palmitoylation of C4BPA in regulating murine sperm motility and complement resistance., PMID:39370067
Serotype 15C Streptococcus pneumoniae resistant to classical complement deposition and agglutination by polyclonal rabbit anti-capsular 15B sera., PMID:39368131
Combined proteomics and metabolomics analysis reveal the effect of a training course on the immune function of Chinese elite short-track speed skaters., PMID:39352112
For research use only. Not for human or drug use.
