Catalog No.
PXX08401
Species reactivity
Streptococcus pyogenes serotype M1
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Streptococcus pyogenes Cas9 (Met1-Asp1368).
Tested applications
ELISA: 1:4000-1:8000, WB: 1:1000-1:4000
Target
CRISPR-associated endonuclease Cas9/Csn1, 3.1.-.-, SpCas9, SpyCas9, cas9, csn1, SPy_1046
Purification
Purified by antigen affinity column.
Accession
Q99ZW2
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A Nanobody Toolbox for Recognizing Distinct Epitopes on Cas9., PMID:39481635
Pre-existing immunity does not impair the engraftment of CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation., PMID:37273902
Pre-existing adaptive immunity to the RNA-editing enzyme Cas13d in humans., PMID:35668177
Investigation of Cas9 antibodies in the human eye., PMID:35217666
AAV-CRISPR Gene Editing Is Negated by Pre-existing Immunity to Cas9., PMID:32348718
Use of anti-CRISPR protein AcrIIA4 as a capture ligand for CRISPR/Cas9 detection., PMID:31207570
Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes., PMID:31015529
Identification of preexisting adaptive immunity to Cas9 proteins in humans., PMID:30692695
A Human DPP4-Knockin Mouse's Susceptibility to Infection by Authentic and Pseudotyped MERS-CoV., PMID:30142928
CRISPR-Mediated Tagging of Endogenous Proteins with a Luminescent Peptide., PMID:28892606
Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration., PMID:28209587
An RNA-aptamer-based two-color CRISPR labeling system., PMID:27229896
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation., PMID:25184501
For research use only. Not for human or drug use.
