Catalog No.
YXX21702
Expression system
E. coli
Species
Streptococcus pyogenes
Protein length
Asp42-Leu91
Predicted molecular weight
28.14 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P19401
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
M protein, serotype 12, emm12
Prevalence and emm typing of multi-drug resistant Streptococcus pyogenes in tertiary care health settings., PMID:40500764
Household molecular epidemiology of Streptococcus pyogenes carriage and infection in The Gambia., PMID:40378280
[Genomic characterization of group A Streptococcus of different emm-type in Tianjin City from 2011 to 2024]., PMID:40374361
Epidemiological and genomic characterisation of an outbreak of Streptococcus pyogenes emm5.23., PMID:40319945
Group A Streptococcus vaccine Development: An Indian public health imperative., PMID:40252837
Additional biomarkers and emm types associated with group A streptococcal toxic shock syndrome: a Japanese nationwide observational study., PMID:40193020
Post-pandemic upsurge in Group A Streptococcus infections at an Italian tertiary university hospital., PMID:40135916
Fibrinogen-binding M-related proteins facilitate the recruitment of plasminogen by Streptococcus pyogenes., PMID:40100134
Structure-Based Development of a Covalent Inhibitor Targeting Streptococcus Pyogenes over Staphylococcus Aureus Sortase A., PMID:40072260
Toxic Shock Syndrome Caused by Streptococcus dysgalactiae Subspecies equisimilis: A Report of a Rare Pediatric Case., PMID:40062160
Streptococcus pyogenes Activates Human Platelets via Streptolysin S-Mediated Calcium Ion Influx., PMID:40031874
Characteristics of Streptococcus pyogenes causing invasive infections among adults in Portugal, 2016-2019: Pre-COVID-19 expansion of the M1UK sublineage., PMID:40021403
Low-dose interleukin 2 therapy halts the progression of post-streptococcal autoimmune complications in a rat model of rheumatic heart disease., PMID:39998162
Streptococcus pyogenes emm Type 3.93 Emergence, the Netherlands and England., PMID:39983683
Unveiling the Group A Streptococcus Vaccine-Based L-Rhamnose from Backbone of Group A Carbohydrate: Current Insight Against Acute Rheumatic Fever to Reduce the Global Burden of Rheumatic Heart Disease., PMID:39959434
Streptococcus pyogenes bloodstream infections in an Italian hospital: A ten-year genomic picture., PMID:39955886
Influence of component structural arrangement on cholesterol-antigen conjugate immunogenicity and antisera bactericidal activity against group A Streptococcus., PMID:39952060
Studying the Oncolytic Activity of Streptococcus pyogenes Strains Against Hepatoma, Glioma, and Pancreatic Cancer In Vitro and In Vivo., PMID:39858844
Group a Streptococcus remains viable inside fibrin clots and gains access to human plasminogen for subsequent fibrinolysis and dissemination., PMID:39804237
Genomic epidemiology of invasive Group A Streptococcus infections in Argentina, 2023: high prevalence of emm1-global and detection of emm1 hypervirulent lineages., PMID:39611833
A phase 1 randomized controlled trial of a peptide-based group A streptococcal vaccine in healthy volunteers., PMID:39563457
Clinical and microbiological characterization of invasive group a Streptococcus infection in children in Japan: A single-center experience., PMID:39549831
High-resolution cryo-EM analysis of a Streptococcus pyogenes M-protein/human plasminogen complex., PMID:39500317
Group A Streptococcus vulvovaginitis in Spain, 2011-2023: antibiotic resistance and emm-type distribution., PMID:39480589
M proteins of group A Streptococcus bind hyaluronic acid via arginine-arginine/serine-arginine motifs., PMID:39436142
Serological Responses to Target Streptococcus pyogenes Vaccine Antigens in Patients With Proven Invasive β-Hemolytic Streptococcal Infections., PMID:39383256
A Rapid Molecular Detection Tool for Toxigenic M1UK Streptococcus pyogenes., PMID:39206960
Nationwide upsurge in invasive disease in the context of longitudinal surveillance of carriage and invasive Streptococcus pyogenes 2009-2023, the Netherlands: a molecular epidemiological study., PMID:39194268
An acute rheumatic fever immune signature comprising inflammatory markers, IgG3, and Streptococcus pyogenes-specific antibodies., PMID:39184444
Immunogenicity of a 30-valent M protein mRNA group A Streptococcus vaccine., PMID:39141987
Molecular characterization of Streptococcus pyogenes (StrepA) non-invasive isolates during the 2022-2023 UK upsurge., PMID:39133528
Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection., PMID:39093975
[Prevalence of the M1UK sublineage among emm1 Streptococcus pyogenes invasive strains isolated in the Czech Republic from December 2022 to May 2023]., PMID:39060098
Molecular Methods Enhance the Detection of Pyoderma-Related Streptococcus pyogenes and emm-Type Distribution in Children., PMID:39008379
Divergent effects of emm types 1 and 12 on invasive group A streptococcal infections-results of a retrospective cohort study, Germany 2023., PMID:38990040
Emergent emm4 group A Streptococcus evidences a survival strategy during interaction with immune effector cells., PMID:38888310
Conservation of C4BP-binding sequence patterns in Streptococcus pyogenes M and Enn proteins., PMID:38879009
Chimeric hepatitis B surface antigen virus-like particles expressing the strep A epitope p*17 elicit a humoral immune response in mice., PMID:38765111
Global epidemiological comparison of Streptococcus pyogenes emm-types associated with pharyngitis and pharyngeal carriage., PMID:38759867
[A rare cause of acute abdomen in a young immunocompetent woman]., PMID:38748278
The hinge-engineered IgG1-IgG3 hybrid subclass IgGh47 potently enhances Fc-mediated function of anti-streptococcal and SARS-CoV-2 antibodies., PMID:38678029
Efficacy of Alum-Adjuvanted Peptide and Carbohydrate Conjugate Vaccine Candidates against Group A Streptococcus Pharyngeal Infection in a Non-Human Primate Model., PMID:38675764
Recombinational exchange of M-fibril and T-pilus genes generates extensive cell surface diversity in the global group A Streptococcus population., PMID:38587426
Quantification of Adaptive Immune Responses Against Protein-Binding Interfaces in the Streptococcal M1 Protein., PMID:38527648
Streptococcal Toxic Shock Syndrome Caused by a Streptococcus pyogenes emm22 Genotype with a CsrS Mutation: a Case Report., PMID:38417865
Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection., PMID:38260261
Molecular characterization of the interaction between human IgG and the M-related proteins from Streptococcus pyogenes., PMID:38176650
Population of invasive group A streptococci isolates from a German tertiary care center is dominated by the hypertoxigenic virulent M1UK genotype., PMID:38064158
A novel invasive Streptococcus pyogenes variant sublineage derived through recombinational replacement of the emm12 genomic region., PMID:38057343
SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions., PMID:37872175
For research use only. Not for human or drug use.
