Catalog No.
YVV05801
Expression system
E. coli
Species
African swine fever virus (ASFV)
Protein length
Met1-Val226
Predicted molecular weight
28.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A0A172MKT6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
A238L, A238L protein
Investigating the RelA Gene's role in African Swine fever tolerance: a study of Indian pigs., PMID:40436218
Preparation and epitope mapping of monoclonal antibodies against African swine fever virus A238L protein., PMID:40311975
How Does African Swine Fever Virus Evade the cGAS-STING Pathway?, PMID:39599510
Nonstructural Protein A238L of the African Swine Fever Virus (ASFV) Enhances Antiviral Immune Responses by Activating the TBK1-IRF3 Pathway., PMID:38921999
Transcriptome signatures of host tissue infected with African swine fever virus reveal differential expression of associated oncogenes., PMID:38381218
Co-Deletion of A238L and EP402R Genes from a Genotype IX African Swine Fever Virus Results in Partial Attenuation and Protection in Swine., PMID:36146830
Identification of Promiscuous African Swine Fever Virus T-Cell Determinants Using a Multiple Technical Approach., PMID:33430316
African swine fever virus (ASFV) protection mediated by NH/P68 and NH/P68 recombinant live-attenuated viruses., PMID:29609966
Evolution of African swine fever virus genes related to evasion of host immune response., PMID:27599940
Identification and utility of innate immune system evasion mechanisms of ASFV., PMID:23165138
Species-specific variation in RELA underlies differences in NF-κB activity: a potential role in African swine fever pathogenesis., PMID:21450812
Cytokine mRNA expression and pathological findings in pigs inoculated with African swine fever virus (E-70) deleted on A238L., PMID:18384883
African swine fever virus A238L inhibitor of NF-kappaB and of calcineurin phosphatase is imported actively into the nucleus and exported by a CRM1-mediated pathway., PMID:17251557
Regulation of inducible nitric oxide synthase expression by viral A238L-mediated inhibition of p65/RelA acetylation and p300 transactivation., PMID:17041221
The viral protein A238L inhibits TNF-alpha expression through a CBP/p300 transcriptional coactivators pathway., PMID:16365438
African swine fever virus proteins involved in evading host defence systems., PMID:15207450
Expression at mRNA level of cytokines and A238L gene in porcine blood-derived macrophages infected in vitro with African swine fever virus (ASFV) isolates of different virulence., PMID:14579171
Mechanism of inactivation of NF-kappa B by a viral homologue of I kappa b alpha. Signal-induced release of i kappa b alpha results in binding of the viral homologue to NF-kappa B., PMID:10934190
A conserved African swine fever virus IkappaB homolog, 5EL, is nonessential for growth in vitro and virulence in domestic swine., PMID:9281518
An IkappaB homolog encoded by African swine fever virus provides a novel mechanism for downregulation of proinflammatory cytokine responses in host macrophages., PMID:8970976
For research use only. Not for human or drug use.
