Catalog No.
PMN53101
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse ERRFI1 (Ser329-Arg399).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
ERBB receptor feedback inhibitor 1, Mitogen-inducible gene 6 protein homolog, MIG-6, Errfi1, Mig6
Purification
Purified by antigen affinity column.
Accession
Q99JZ7
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer., PMID:39905540
MIG6 loss confers resistance to ALK/ROS1 inhibitors in NSCLC through EGFR activation by low-dose EGF., PMID:37917191
Feedback activation of EGFR/wild-type RAS signaling axis limits KRASG12D inhibitor efficacy in KRASG12D-mutated colorectal cancer., PMID:37020035
Glucocorticoid Receptor Modulates EGFR Feedback upon Acquisition of Resistance to Monoclonal Antibodies., PMID:31052457
Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1., PMID:20110370
Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin., PMID:15856022
Modulation of Elk-dependent-transcription by Gene33., PMID:15696545
Regulation of Gene33 expression by insulin requires MEK-ERK activation., PMID:15358516
For research use only. Not for human or drug use.
