Catalog No.
PMN07301
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse ROBO2 (Gly13-Thr220).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
ROBO2 isoform b, Roundabout guidance receptor 2, Robo2
Purification
Purified by antigen affinity column.
Accession
Q19AB2
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Monoclonal antibodies that block Roundabout 1 and 2 signaling target pathological ocular neovascularization through myeloid cells., PMID:39565875
Downregulation of Roundabout guidance receptor 2 suppresses hepatocellular carcinoma progression by interacting with Y-box binding protein 1., PMID:38297025
A novel immune-related model to predict prognosis and responsiveness to checkpoint and angiogenesis blockade therapy in advanced renal cancer., PMID:36998443
Modeling HNF1B-associated monogenic diabetes using human iPSCs reveals an early stage impairment of the pancreatic developmental program., PMID:34450036
A Phase 1 first-in-human study of the safety, tolerability, and pharmacokinetics of the ROBO2 fusion protein PF-06730512 in healthy participants., PMID:34369667
Runs of Homozygosity in Modern Chicken Revealed by Sequence Data., PMID:33077478
Development of a Cell-Based Assay for the Detection of Neutralizing Antibodies to PF-06730512 Using Homogenous Time-Resolved Fluorescence., PMID:32166588
Methyl-CpG Binding Protein 2 (Mecp2) Regulates Sensory Function Through Sema5b and Robo2., PMID:26733807
Activation of Slit2-Robo1 signaling promotes liver fibrosis., PMID:26264936
srGAP3 promotes neurite outgrowth of dorsal root ganglion neurons by inactivating RAC1., PMID:25149377
An association between genetic variation in the roundabout, axon guidance receptor, homolog 2 gene and immunity traits in chickens., PMID:24570420
Genome-wide association study of antibody response to Newcastle disease virus in chicken., PMID:23663563
Roundabout receptors are critical for foregut separation from the body wall., PMID:23328398
Developmental guidance of embryonic corneal innervation: roles of Semaphorin3A and Slit2., PMID:20471970
Functional diversity of Robo receptor immunoglobulin domains promotes distinct axon guidance decisions., PMID:20206526
Netrin-1 and slit-2 regulate and direct neurite growth of ventral midbrain dopaminergic neurons., PMID:15737744
Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding., PMID:15207848
Dynamic expression patterns of Robo (Robo1 and Robo2) in the developing murine central nervous system., PMID:14689480
Robo1 and Robo2 are homophilic binding molecules that promote axonal growth., PMID:12504588
For research use only. Not for human or drug use.
