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Anti-ASC/TMS1/PYCARD Polyclonal Antibody

Catalog #:   PHJ80801 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q9ULZ3
Overview

Catalog No.

PHJ80801

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ASC/TMS1/PYCARD (Leu112-Ser195).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

TMS1,CARD5,Caspase recruitment domain-containing protein 5,Apoptosis-associated speck-like protein containing a CARD,PYD and CARD domain-containing protein,ASC,PYCARD,hASC,Target of methylation-induced silencing 1

Purification

Purified by antigen affinity column.

Accession

Q9ULZ3

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with ASC/TMS1/PYCARD antibody (PHJ80801) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 12 kDa
    Observed MW: 12 kDa
References

Adipose-Derived Mesenchymal Stromal/Stem Cells Reduce Inflammatory Responses and Partially Alleviate Skin Symptoms in Imiquimod-Induced Psoriasis-Like Dermatitis Model Mice., PMID:40500215

Shikonin inhibits NLRP3 inflammasome activation and controls inflammatory disease., PMID:40447675

Isolation and Characterization of Equine Mesenchymal Stromal/Stem Cells., PMID:40445292

Targeted fusion of antibody-secreting cells: Unlocking monoclonal antibody production with hybridoma technology., PMID:40418588

Use of sintilimab in primary adenosquamous carcinoma of the liver results in pathological complete response: a case report and literature review., PMID:40370460

Modulating adipose-derived stromal cells' secretomes by culture conditions: effects on angiogenesis, collagen deposition, and immunomodulation., PMID:40267340

Effectiveness and tolerability of atogepant in the prevention of migraine: A real life, prospective, multicentric study (the STAR study)., PMID:40267275

Macrophage-Hosted Porphyromonas gingivalis Is a Risk Factor for Cataract Development., PMID:40266593

Clinical perspective: Advancing hemophilia treatment through gene therapy approaches., PMID:40263938

Influenza A hemagglutinin virus-like particles confer protection against influenza B virus infection., PMID:40230200

Urine-derived stem cells from patients alleviate lupus nephritis via regulating macrophage polarization in a CXCL14-dependent manner., PMID:40204070

Decoding plasma cell maturation dynamics with BCMA., PMID:40134424

Activated αβ T- and reduced mucosa-associated invariant T cells in LGI1- and CASPR2-encephalitis., PMID:40094812

EZH2 coordinates memory B-cell programming and recall responses., PMID:40073167

Gut IgA-antibody secreting cells segregate into four Blimp1+ subsets based on differential expression of IgA and Ki-67 and are retained following prolonged αCD20 B cell depletion in mice., PMID:40073093

CD21lo B cell subsets are recruited to the central nervous system in acute neuromyelitis optica., PMID:40042820

Profile of Humoral Immunity and B Cell Pool in Infection with the SARS-CoV-2 Prototype Strain and AZD1222 (ChAdOx nCoV-19) Vaccination., PMID:40006648

Deep profiling of B cells responding to various pathogens uncovers compartments in IgG memory B cell and antibody-secreting lineages., PMID:39970201

Antibody responses in Klebsiella pneumoniae bloodstream infection: a prospective cohort study., PMID:39952262

Metformin Ameliorates Ulcerative Colitis Through Inhibiting NLRP3 Inflammasome Activation., PMID:39931167

A Site-Specific MiniAp4-Trastuzumab Conjugate Prevents Brain Metastasis., PMID:39924896

Accurate evaluation of factor VIII activity of efanesoctocog alfa in the presence of emicizumab., PMID:39798924

Cost effectiveness of different treatment strategies with natalizumab for pregnant women with multiple sclerosis., PMID:39776288

Receptor Binding Domain-Specific B Cell Memory Responses Among Individuals Vaccinated Against SARS-CoV-2., PMID:39772064

Immunological memory in a teleost fish: common carp IgM+ B cells differentiate into memory and plasma cells., PMID:39759525

Depletion of Adipose Stroma-Like Cancer-Associated Fibroblasts Potentiates Pancreatic Cancer Immunotherapy., PMID:39620946

Therapeutic effects of extracellular vesicles derived from mesenchymal stem cells primed with disease-conditioned-immune cells in systemic lupus erythematosus., PMID:39558370

Cost-Effectiveness of Trastuzumab Deruxtecan in Patients with Unresectable or Metastatic HER2-Low Breast Cancer Who Have Received Prior Chemotherapy., PMID:39531128

Alleviation of COVID-19 Symptoms and Reduction in Healthcare Utilization Among High-risk Patients Treated With Nirmatrelvir/Ritonavir (NMV/R): A Phase 3 Randomized Trial., PMID:39523543

Concizumab prophylaxis in people with haemophilia A or haemophilia B without inhibitors (explorer8): a prospective, multicentre, open-label, randomised, phase 3a trial., PMID:39521008

Protocol for developing Pseudomonas aeruginosa type III secretion system-neutralizing monoclonal antibodies from human B cells., PMID:39520687

Progressive polyadenylation and m6A modification of Ighg1 mRNA maintain IgG1 antibody homeostasis in antibody-secreting cells., PMID:39476842

Navigating the Landscape of B Cell Mediated Immunity and Antibody Monitoring in SARS-CoV-2 Vaccine Efficacy: Tools, Strategies and Clinical Trial Insights., PMID:39460256

Unravelling Transplant-Ineligible Newly Diagnosed Multiple Myeloma Treatment in Real-World Practice in Spain: The CARINAE Study., PMID:39458913

Clinical significance of blood cell ratios in healthy and sick Leishmania infantum-seropositive dogs., PMID:39444011

[Electroacupuncture preconditioning prevents urticaria by regulating inflammatory response in rats with urticaria]., PMID:39433365

Early divergent modulation of NLRP2's and NLRP3's inflammasome sensors vs. AIM2's one by signals from Aβ·Calcium-sensing receptor complexes in human astrocytes., PMID:39426463

SIV-specific antibodies protect against inflammasome-driven encephalitis in untreated macaques., PMID:39383041

Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601

SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination., PMID:39333316

A cost-minimization analysis of anti-VEGFs for the treatment of neovascular age-related macular degeneration in the Netherlands., PMID:39322853

SMARCA5-mediated chromatin remodeling is required for germinal center formation., PMID:39297882

Efficacy of galcanezumab in migraine central sensitization., PMID:39294310

Datopotamab-deruxtecan plus durvalumab in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial., PMID:39277672

Datopotamab-deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial., PMID:39277671

Engineering potent chimeric antigen receptor T cells by programming signaling during T-cell activation., PMID:39266656

Function-first discovery of high affinity monoclonal antibodies using Nanovial-based plasma B cell screening., PMID:39229089

High-throughput single-cell screening of viable hybridomas and patient-derived antibody-secreting cells using punchable microwells., PMID:39206935

C-ter100 peptide derived from Vibrio vEP-45 protease acts as a pathogen-associated molecular pattern to induce inflammation and innate immunity., PMID:39186780

Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells., PMID:39143416

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-ASC/TMS1/PYCARD Polyclonal Antibody [PHJ80801]
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