Catalog No.
PHA18201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PPP6C (Met1-Leu305).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Serine/threonine-protein phosphatase 6 catalytic subunit, PP6C, 3.1.3.16, Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed, PPP6C, PPP6
Purification
Purified by antigen affinity column.
Accession
O00743
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Targeting the transcription factor HES1 by L-menthol restores protein phosphatase 6 in keratinocytes in models of psoriasis., PMID:36535970
Comprehensive CRISPR-Cas9 screen identifies factors which are important for plasmablast development., PMID:36189249
Leucine Carboxyl Methyltransferase 1 (LCMT-1) Methylates Protein Phosphatase 4 (PP4) and Protein Phosphatase 6 (PP6) and Differentially Regulates the Stable Formation of Different PP4 Holoenzymes., PMID:27507813
Protein phosphatase 6 controls BCR-induced apoptosis of WEHI-231 cells by regulating ubiquitination of Bcl-xL., PMID:24808369
[Melanoma: from molecular studies to the treatment breakthrough]., PMID:24341237
Regulation of cortical contractility and spindle positioning by the protein phosphatase 6 PPH-6 in one-cell stage C. elegans embryos., PMID:20040490
Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon., PMID:16769727