Catalog No.
YMF71301
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Thr82-Ala331
Predicted molecular weight
29.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P51661
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
11-beta-hydroxysteroid dehydrogenase type 2, 11-DH2, 11-beta-HSD2, 1.1.1.-, Corticosteroid 11-beta-dehydrogenase isozyme 2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, Hsd11b2, Hsd11k
Erchen Decoction ameliorates the rat model of polycystic ovary syndrome by regulating the steroid biosynthesis pathway., PMID:40446578
Huangkui capsule, an extract from Abelmoschus manihot (L.) medic, inhibits adrenal aldosterone synthesis and renal ERK/EGR1 pathway in the treatment of diabetic kidney disease., PMID:40348304
Maternal stress and fetoplacental cortisol regulation in small-for-gestational-age newborns., PMID:40344310
Characterizing the expression profile of 3R tau pathology in Pick's disease., PMID:40315309
A polyepigenetic glucocorticoid exposure score and HPA axis-related DNA methylation are associated with gestational epigenetic aging., PMID:40007075
Dietary DHA Regulated the Androgen Production in Male Chinese Tongue Sole Cynoglossus semilaevis., PMID:39949363
Case report: Clinical characteristics and Genetical analysis of HSD11B2 in three Chinese children with apparent mineralocorticoid excess: a case series., PMID:39931437
Dose-dependent role of AMH and AMHR2 signaling in male differentiation and regulation of sex determination in Spotted knifejaw (Oplegnathus punctatus) with X1X1X2X2/X1X2Y chromosome system., PMID:39893368
Early Life Stress, DNA Methylation of NR3C1 and HSD11B2 , and Oral Feeding Skill Development in Preterm Infants : A Pilot Study., PMID:39724562
Effects of the combination of Epimedium brevicornum Maxim, Ligustrum lucidum Ait and Dexamethasone on asthmatic rats by endogenous glucocorticoid pathway., PMID:39694426
Molecular Ontology of the Nucleus of Solitary Tract., PMID:39629676
Epigenetics Embedding of Oral Feeding Skill Development in Preterm Infants: A Study Protocol., PMID:39602096
Placental epigenetic signatures of maternal distress in glucocorticoid-related genes and newborn outcomes: A study of Spanish primiparous women., PMID:39504602
Impaired 11β-Hydroxysteroid Dehydrogenase Type 2 Activity in Kidney Disease Disrupts 11-Oxygenated Androgen Biosynthesis., PMID:39382395
Progressive 11β-Hydroxysteroid Dehydrogenase Type 2 Insufficiency as Kidney Function Declines., PMID:39312227
Decoding 11-oxygenated androgen synthesis: insights from enzyme gene expression and LC-MS/MS quantification., PMID:39219353
Fast and reliable quantification of aldosterone, cortisol and cortisone via LC-MS/MS to study 11β-hydroxysteroid dehydrogenase activities in primary cell cultures., PMID:39214289
Pre-receptor regulation of 11-oxyandrogens differs between normal and cancerous endometrium and across endometrial cancer grades and molecular subtypes., PMID:39205690
Psoriatic skin transcript phenotype: androgen/estrogen and cortisone/cortisol imbalance with increasing DNA damage response., PMID:39180588
Epigenetic Regulation of the Renin-Angiotensin-Aldosterone System in Hypertension., PMID:39125667
11β-Hydroxysteroid dehydrogenase type 2 may mediate the stress-specific effects of cortisol on brain cell proliferation in adult zebrafish (Danio rerio)., PMID:39092490
Increased risk of severe neonatal opioid withdrawal syndrome in pregnancies with low placental ABCB1 DNA methylation., PMID:39033231
An in Vitro triple screen model for human mineralocorticoid receptor activity., PMID:38866188
DNA methylation-mediated 11βHSD2 downregulation drives the increases in angiotensin-converting enzyme and angiotensin II within preeclamptic placentas., PMID:38814727
The Role of microRNA in the Regulation of Cortisol Metabolism in the Adipose Tissue in the Course of Obesity., PMID:38791098
Apparent mineralocorticoid excess in Israel: a case series and literature review., PMID:38652803
Upregulation of coagulation factor V by glucocorticoid in the preovulatory follicles of zebrafish., PMID:38631601
Reproductive endocrine disruption effect and mechanism in male zebrafish after life cycle exposure to environmental relevant triclosan., PMID:38492288
Microbiota modulates the steroid response to acute immune stress in male mice., PMID:38361932
The intrafollicular concentrations of biologically active cortisol in women rise abruptly shortly before ovulation and follicular rupture., PMID:38268234
Investigating the Diagnostic and Therapeutic Potential of SREBF2-Related Lipid Metabolism Genes in Colon Cancer., PMID:38107762
Intracellular negative feedback mechanisms in blubber and muscle moderate acute stress responses in fasting seals., PMID:38009222
Predisposing factors for adrenal crisis in chronic adrenal insufficiency: a case-control study., PMID:38006230
Neonatal stress exposure and DNA methylation of stress-related and neurodevelopmentally relevant genes: An exploratory study., PMID:37797474
Gonadal transcriptome analysis of paradise fish Macropodus opercularis to reveal sex-related genes., PMID:37666127
Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study., PMID:37369098
Down-Regulation of the Mineralocorticoid Receptor (MR) and Up-Regulation of Hydroxysteroid 11-Beta Dehydrogenase Type 2 (HSD11B2) Isoenzyme in Critically Ill Patients., PMID:37130784
Scoping Review of Early Toxic Stress and Epigenetic Alterations in the Neonatal Intensive Care Unit., PMID:37084322
Urinary extracellular vesicles carry valuable hints through mRNA for the understanding of endocrine hypertension., PMID:37065732
Thiram, an inhibitor of 11ß-hydroxysteroid dehydrogenase type 2, enhances the inhibitory effects of hydrocortisone in the treatment of osteosarcoma through Wnt/β-catenin pathway., PMID:36978114
Direct inhibition of human and rat 11β-hydroxysteroid dehydrogenase 2 by per- and polyfluoroalkyl substances: Structure-activity relationship and in silico docking analysis., PMID:36878351
Expression pattern analysis of anti-Mullerian hormone in testis development of pearlscale angelfish (Centropyge vrolikii)., PMID:36840532
[The role of methylation of placental glucocorticoid response gene in the association between pregnancy-related anxiety in the third trimester and birth outcomes]., PMID:36797578
Stress response of Rhamdia quelen to the interaction stocking density - Feeding regimen., PMID:36781023
Utero-placental expression and functional implications of HSD11B1 and HSD11B2 in canine pregnancy†., PMID:36722005
Identification and clinical validation of key genes as the potential biomarkers in colorectal adenoma., PMID:36631756
Dietary polyphenols and their relationship to the modulation of non-communicable chronic diseases and epigenetic mechanisms: A mini-review., PMID:36582744
Hypothalamic-Pituitary-Adrenal Hormones Impair Pig Fertilization and Preimplantation Embryo Development via Inducing Oviductal Epithelial Apoptosis: An In Vitro Study., PMID:36497149
Effects of High-Fructose Corn Syrup Intake on Glucocorticoid Metabolism in Rats During Childhood, Adolescence and Adulthood., PMID:36368682
Apparent mineralocorticoid excess: comprehensive overview of molecular genetics., PMID:36329487
For research use only. Not for human or drug use.
