Catalog No.
YME14801
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Gly485-Asn639
Predicted molecular weight
18.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q64446
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Copper-transporting ATPase 2, 7.2.2.8, Copper pump 2, Wilson disease-associated protein homolog, Atp7b, Wnd
Pitfalls in the Diagnosis of Wilson Disease., PMID:40504409
C5a/C5aR pathway blocking promoted CuS-mediated cancer therapy effect by inhibiting cuproptosis resistance., PMID:40484643
Role and mechanisms of cuproptosis in the pathogenesis of Wilson's disease (Review)., PMID:40476570
MiR-133a-5p Facilitates Cuproptosis in Hepatocellular Carcinoma Through Targeting of ATP7B., PMID:40433054
Some Properties of the C. elegans Multicopper Oxidase F21D5.3, an Ortholog of Human Ceruloplasmin., PMID:40429919
Changes in the FXR-cistrome and alterations in bile acid physiology in Wilson disease., PMID:40408300
Nisin Self-assembles to Interfere with Cellular Endocytosis for Ribosome-Mediated Anti-inflammatory Efficiency., PMID:40403150
Copper's new role in cancer: how cuproptosis-related genes could revolutionize glioma treatment., PMID:40355831
Current Management of Neurological Wilson's Disease., PMID:40351566
ATPase copper transporting beta attenuates malignant features with high expression as an indicator of favorable prognosis in breast cancer., PMID:40316883
Oxidized-LDL aggravates renal injury via tubular cuproptosis., PMID:40306349
From severe aplastic anemia with TERT variant to Wilson disease - associations or not., PMID:40257477
[Analysis of clinical phenotype and ATP7B variants characteristics of 337 patients with hepatolenticular degeneration in Anhui province]., PMID:40222831
Physiological and Histological Responses of Awassi Lambs to High Dietary Organic Copper Supplementation., PMID:40218459
Isolated neurological symptoms of Wilson's disease manifesting as focal epileptic seizures without hepatic involvement: Insights from a case report., PMID:40215409
Induction of Cuproptosis by Dichloromethane Extract From Patrinia scabiosaefolia Fisch on K562 Cells., PMID:40177825
Challenges and Recent Advances in Diagnosing Wilson Disease., PMID:40160676
Case report: Co-occurrence of Wilson's and Alexander's diseases revealed by genetic analysis., PMID:40144630
Hepatic microtubule destabilization facilitates liver fibrosis in the mouse model of Wilson disease., PMID:40140071
Epigallocatechin Gallate Promotes Cuproptosis via the MTF1/ATP7B Axis in Hepatocellular Carcinoma., PMID:40136640
Engineering Dual-Responsive Nanoplatform Achieves Copper Metabolism Disruption and Glutathione Consumption to Provoke Cuproptosis/Ferroptosis/Apoptosis for Cancer Therapy., PMID:40134095
A self-accelerating 'copper bomb' strategy activated innate and adaptive immune response against triple-negative breast cancer., PMID:40130080
Blocking copper transporter protein-dependent drug efflux with albumin-encapsulated Pt(IV) for synergistically enhanced chemo-immunotherapy., PMID:40102840
Clinical, biochemical and cell biological characterization of KIDAR syndrome associated with a novel AP1B1 variant., PMID:40101690
Hepatic progenitor cells reprogrammed from mouse fibroblasts repopulate hepatocytes in Wilson's disease mice., PMID:40069754
Elevated COMMD1 Contributes to Cardiomyocyte Copper Efflux in Chronic Myocardial Ischemia: Insights From Rhesus Monkey., PMID:40032621
N,N'-bis(2-mercaptoethyl)isophthalamide (NBMI) as a novel chelator for Wilson's disease., PMID:40032031
Synergistic effects of lead and copper co-exposure on promoting oxidative stress and apoptosis in the neuronal cells., PMID:40010429
Effects of Dietary Copper Sources and Levels on Liver Copper Metabolism and the Expression of Transporters in Growing Pigs., PMID:40003008
Pathogenicity analysis of ATP7B in pediatric patients with Wilson's disease and functional verification of alternative splice variants., PMID:39978457
Spectrum and classification of ATP7B variants with clinical correlation in children with Wilson disease., PMID:39933775
Genetic map of Wilson disease in Spain - A great tool to improve diagnosis and screening., PMID:39930861
Clinical and Molecular Spectrum of Wilson Disease in the Arab World: A Systematic Review., PMID:39922954
Prion protein promotes copper toxicity in Wilson disease., PMID:39922819
Sensitive and Deep Coverage Phosphoproteome Detection Method Reveals Spleen as a More Sensitive Organ than Liver in Early Detection of Liver Fibrosis-Related Signaling Protein Dysregulation., PMID:39823565
Metallothionein rescues doxorubicin cardiomyopathy via mitigation of cuproptosis., PMID:39793852
Genetic profiling of Wilson disease reveals a potential recurrent pathogenic variant of ATP7B in the Jordanian population., PMID:39763201
[Research progresses in gene therapy for hepatolenticular degeneration]., PMID:39743356
Orthogonal and multiplexable genetic perturbations with an engineered prime editor and a diverse RNA array., PMID:39737993
Novel cuprotosis-related gene signature: a prognostic indicator and regulator of the glioma immune microenvironment., PMID:39697708
Roles of Copper Transport Systems Members in Breast Cancer., PMID:39676279
Psychiatric Symptoms in Wilson's Disease-Consequence of ATP7B Gene Mutations or Just Coincidence?-Possible Causal Cascades and Molecular Pathways., PMID:39596417
Copper homeostasis and neurodegenerative diseases., PMID:39589160
CircSpna2 attenuates cuproptosis by mediating ubiquitin ligase Keap1 to regulate the Nrf2-Atp7b signalling axis in depression after traumatic brain injury in a mouse model., PMID:39581695
Lung cancer, platinum analog-based frontline treatment and pharmacogenetic limitations., PMID:39560009
The Genomic Landscape of Wilson Disease in a Pan India Disease Cohort and Population-Scale Data., PMID:39535360
Systematic Analysis and Insights Into the Mutation Spectrum and Ethnic Differences in ATP7B Mutations Associated With Wilson Disease., PMID:39502306
Wilson Disease: Novel Diagnostic and Therapeutic Approaches., PMID:39496313
In Situ Transformable Fibrillar Clusters Disrupt Intracellular Copper Metabolic Homeostasis by Comprehensive Blockage of Cuprous Ions Efflux., PMID:39491511
[Expanded carrier screening for 216 diseases in a cohort of 3 097 healthy Chinese individuals of childbearing age]., PMID:39463360
For research use only. Not for human or drug use.
