Catalog No.
PHJ71501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PIM2 (Leu82-Asp292).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Pim-2h,Serine/threonine-protein kinase pim-2,PIM2
Purification
Purified by antigen affinity column.
Accession
Q9P1W9
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Final step of B-cell differentiation into plasmablasts; the right time to activate plasma cell PIM2 kinase., PMID:37207916
High ETV6 Levels Support Aggressive B Lymphoma Cell Survival and Predict Poor Outcome in Diffuse Large B-Cell Lymphoma Patients., PMID:35053500
Engineered Fully Human Single-Chain Monoclonal Antibodies to PIM2 Kinase., PMID:34770845
Inhibition of PIM Kinases in DLBCL Targets MYC Transcriptional Program and Augments the Efficacy of Anti-CD20 Antibodies., PMID:34625423
The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination., PMID:34402853
Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family., PMID:34299628
Inhibition of Pim-2 kinase by LT-171-861 promotes DNA damage and exhibits enhanced lethal effects with PARP inhibitor in multiple myeloma., PMID:34111425
Targeting PIM Kinase with PD1 Inhibition Improves Immunotherapeutic Antitumor T-cell Response., PMID:30327305
PIM2 survival kinase is upregulated in a p53-dependent manner in cells treated with camptothecin or co-treated with actinomycin D and nutlin-3a., PMID:30096294
Patterns and Significance of PIM Kinases in Urothelial Carcinoma., PMID:26551340
Biologic correlates and significance of axonogenesis in prostate cancer., PMID:24767770
Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma., PMID:22808135
Identification of a phenanthrene derivative as a potent anticancer drug with Pim kinase inhibitory activity., PMID:21981263
Phase I study of intraventricular administration of rituximab in patients with recurrent CNS and intraocular lymphoma., PMID:17312328
New prognostic relevant factors in primary cutaneous diffuse large B-cell lymphomas., PMID:17289214
Differences in serological responses to specific glycopeptidolipid-core and common lipid antigens in patients with pulmonary disease due to Mycobacterium tuberculosis and Mycobacterium avium complex., PMID:16434712
Clinical evaluation of serodiagnosis of active tuberculosis by multiple-antigen ELISA using lipids from Mycobacterium bovis BCG Tokyo 172., PMID:16232093
Pim-2 upregulation: biological implications associated with disease progression and perinueral invasion in prostate cancer., PMID:16015593
The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death., PMID:12954615
Identification of new genes differentially expressed in coronary artery disease by expression profiling., PMID:12902549
Natural killer T cells restricted by the monomorphic MHC class 1b CD1d1 molecules behave like inflammatory cells., PMID:11751982
Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice., PMID:1904009
Isolation and structural characteristics of a monoclonal antibody-defined cross-reactive phospholipid antigen from Mycobacterium tuberculosis and Mycobacterium leprae., PMID:1702433
For research use only. Not for human or drug use.
