Catalog No.
YHN51701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val360-Gly474
Predicted molecular weight
15.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96FN5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Kinesin-like protein KIF12, KIF12
Mutations in the kinesin KIF12 promote MASH in humans and mice by disrupting lipogenic enzyme turnover., PMID:39920308
The spectrum of novel ABCB11 gene variations in children with progressive familial intrahepatic cholestasis type 2 in Pakistani cohorts., PMID:39143102
Youngest Living Donor Liver Transplant for End-Stage Liver Disease in a 6-Month-Old With a Novel Aggressive Mutation in KIF12 Gene., PMID:38853137
Kinesin family member 12-related hepatopathy: A generally indolent disorder with elevated gamma-glutamyl-transferase activity., PMID:38553872
Cholestatic Liver Disease in a Child with KIF12 Mutation., PMID:37919484
Clinical exome sequencing reveals a novel pathogenic variant in KIF12 underlying cholestasis with highly variable phenotypes., PMID:37866826
Diagnostic yield and novel candidate genes by next generation sequencing in 166 children with intrahepatic cholestasis., PMID:37314652
Spatio-Temporal Expression Pattern of CAKUT Candidate Genes DLG1 and KIF12 during Human Kidney Development., PMID:36830709
KIF12 Variants and Disturbed Hepatocyte Polarity in Children with a Phenotypic Spectrum of Cholestatic Liver Disease., PMID:34555379
The plasma peptides of Alzheimer's disease., PMID:34182925
Identification of novel loci for pediatric cholestatic liver disease defined by KIF12, PPM1F, USP53, LSR, and WDR83OS pathogenic variants., PMID:30250217
Alterations in Placental Gene Expression of Pregnant Women with Chronic Chagas Disease., PMID:29545200
Human and mouse microarrays-guided expression analysis of membrane protein trafficking-related genes in MDCK cells, a canine epithelial model for apical and basolateral differential protein targeting., PMID:29450149
Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk Mouse., PMID:26295839
Antioxidant signaling involving the microtubule motor KIF12 is an intracellular target of nutrition excess in beta cells., PMID:25373778
Hypermethylation of EBF3 and IRX1 genes in synovial fibroblasts of patients with rheumatoid arthritis., PMID:23456299
A mechanosensory system governs myosin II accumulation in dividing cells., PMID:22379107
Systematic candidate gene investigations in the SPA2 locus (9q32) show an association between TNFSF8 and susceptibility to spondylarthritis., PMID:21480186
Specific kinesin expression profiles associated with taxane resistance in basal-like breast cancer., PMID:21479552
HNF-1beta regulates transcription of the PKD modifier gene Kif12., PMID:19005009
Dictyostelium Aurora kinase has properties of both Aurora A and Aurora B kinases., PMID:18326585
The localization of inner centromeric protein (INCENP) at the cleavage furrow is dependent on Kif12 and involves interactions of the N terminus of INCENP with the actin cytoskeleton., PMID:17567958
Kinesin family member 12 is a candidate polycystic kidney disease modifier in the cpk mouse., PMID:15728779
Characterization of KIF12 gene in silico., PMID:15643526
A mitotic kinesin-like protein required for normal karyokinesis, myosin localization to the furrow, and cytokinesis in Dictyostelium., PMID:15546981
For research use only. Not for human or drug use.
