Catalog No.
YHN50901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gly321
Predicted molecular weight
36.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A6NDG6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Glycerol-3-phosphate phosphatase, G3PP, 3.1.3.21, Aspartate-based ubiquitous Mg(2+)-dependent phosphatase, AUM, 3.1.3.48, Phosphoglycolate phosphatase, PGP, PGP
Selective Inhibition of the ABCG2 Transporter by Primaquine Derivatives Reverses the Multidrug Resistance of Tumor Cells., PMID:40508176
Identification of antibody-drug conjugate payloads which are substrates of ATP-binding cassette drug efflux transporters., PMID:40501953
Transepithelial transport and mechanism of pyrethroids across Caco-2 cells mediated by transporters., PMID:40500064
Enantioselective transplacental transfer of xenobiotics: mechanisms, plasma protein binding, and health implications for fetal development., PMID:40483352
Plant growth-promoting Burkholderia Sp. ZF6 enhances Brassica juncea survival in Cd/Zn contaminated soils via heavy metal tolerance genes., PMID:40468126
Development of Dry Powder Inhaler formulation for site specific delivery of nanoconjugates loaded with Curcumin and BCL2 siRNA in Lung Cancer., PMID:40466858
Decrease in In Vivo Efflux Transport via P-glycoprotein at the Rat Inner Blood-Retinal Barrier by Peripheral Administration of Lipopolysaccharide., PMID:40461747
A Bottom-up Approach for Mutant and Wild Type Collies Using Physiologically Based Pharmacokinetic (PBPK) Modeling: A Case Study Using Loperamide., PMID:40457124
[Frontline in Biliary Excretion of Drugs and Their Evaluation Systems]., PMID:40451870
Design, synthesis, and in vitro and in vivo anti-drug resistant cervical cancer activity of novel licochalcone A derivatives based on dual targeting of VEGFR-2/P-gp., PMID:40451014
Investigation of differentiation conditions for canine duodenum, upper jejunum, and ileum crypt-derived cells for drug transport and metabolism., PMID:40450898
Cryo-EM Structures of Apo and DDT-Bound P-Glycoprotein in Yellowfin Tuna., PMID:40439033
P-Glycoprotein as a Therapeutic Target in Hematological Malignancies: A Challenge to Overcome., PMID:40429842
[Circ_EPHB4 regulates temozolomide sensitivity in glioma cells through the miR-424-5p/Wnt3 axis]., PMID:40415425
P-gp quantification for cell resistance studies in leukemia cells using the innovative LightSpot-FL-1 fluorescent conjugate., PMID:40414975
Preclinical pharmacokinetics and in vitro ADME properties of PAT-1102: a novel HDAC inhibitor for cancer therapy., PMID:40411569
Alterations of drug-resistant proteins in nasopharyngeal carcinoma after intensity-modulated radiation therapy with or without chemotherapy and correlation with clinicopathologic features and short-term prognosis., PMID:40407950
Analysis of Mechanoreceptors and Free Nerve Endings in the Lateral Collateral Ligament of the Elbow Using Immunofluorescence and Confocal Microscopy., PMID:40403831
Inhibition of Sox4 Increases the Sensitivity of Drug-resistant Melanoma Cells to Cisplatin through the P38 Signaling Pathway., PMID:40396326
Inhibition of Dormant Lung Cancer Cell Reactivation by Punica Granatum Peel and Dioscorea Nipponica: Involving MYC, SKP2 and p27., PMID:40391177
Co-expression of HIF1A with multi-drug transporters (P-GP, MRP1, and BCRP) in chemoresistant breast, colorectal, and ovarian cancer cells., PMID:40390503
Deciphering the Relative Contribution of CYP3A4 Versus P-Glycoprotein for the Shared Substrate Cyclosporine-Commentary on Lown et al., PMID:40388112
Design, synthesis, and biological evaluation of C-12 modified ocotillol-type derivatives as novel P-glycoprotein modulators for overcoming multidrug resistance., PMID:40382839
Cinnamaldehyde enhances the intervention effect of puerarin on stroke from the perspectives of pharmacokinetics and pharmacodynamics., PMID:40381675
A novel, covalent broad-spectrum inhibitor targeting human coronavirus Mpro., PMID:40374668
Ultrasound-assisted combined with natural deep eutectic solvents for Platycodon grandiflorum polysaccharides extraction: Process optimization and evaluation of anti-lung cancer activity., PMID:40373906
Molecular pharmacokinetic mechanism of JBP485 against aristolochic acid I (AAI) -induced nephrotoxicity., PMID:40371353
2',6'-dihydroxy-3',4'-dimethoxydihydrochalcone counteracts cancer multidrug resistance by impeding STAT3 activation and ABC transporter-mediated drug efflux., PMID:40367556
Preclinical pharmacokinetics, metabolism, and disposition of NXE0041178, a novel orally bioavailable agonist of the GPR52 receptor with potential for treatment of schizophrenia and related psychiatric disorders., PMID:40367121
N-Acetylcysteine Attenuates Aβ-Mediated Oxidative Stress, Blood-Brain Barrier Leakage, and Renal Dysfunction in 5xFAD Mice., PMID:40362589
Mapping the Role of P-gp in Multidrug Resistance: Insights from Recent Structural Studies., PMID:40362415
Therapeutic effects of medicinal and food-based traditional herbal couples on type 2 diabetes mellitus based on pharmacodynamics and pharmacokinetics., PMID:40351422
Silencing HMGB1 secretion inhibited EV71-induced blood-brain barrier dysfunction and neural inflammation by depressing astrocyte activation via sHh signal blockage., PMID:40349912
A Systematic Review and Classification of the Effects of P-glycoprotein Inhibitors and Inducers in Humans, Using Digoxin, Fexofenadine, and Dabigatran as Probe Drugs., PMID:40349292
Bioanalytical considerations for quantification of ondansetron in rat microdialysis study using LC-MS/MS., PMID:40342394
Measurement of cyclosporin induced changes in P-glycoprotein function at the human blood-brain barrier using [18F]MC225 and PET., PMID:40338304
Antagonism of Bacillus velezensis ZGE166 Against the Pathogenic Fungi Causing Corm Rot Disease in Saffron (Crocus sativus L.)., PMID:40335733
Investigation of the attenuation effect of licorice on the toxicity of rhubarb using a P-gp lipid raft bioaffinity chromatography., PMID:40334758
Reversal of doxorubicin-resistance of MCF-7/Adr cells via multiple regulations by glucose oxidase loaded AuNRs@MnO2@SiO2 nanocarriers., PMID:40334474
The plant matrix of Artemisia annua L. for the treatment of malaria: Pharmacodynamic and pharmacokinetic studies., PMID:40334250
Molecular Mechanisms of Reversal of Multidrug Resistance in Breast Cancer by Inhibition of P-gp by Cytisine N-Isoflavones Derivatives Explored Through Network Pharmacology, Molecular Docking, and Molecular Dynamics., PMID:40332431
Influences of Magnesium Isoglycyrrhizinate on the Pharmacokinetics of Almonertinib in Rats and Its Potential Mechanisms., PMID:40331403
Advances in the Localization and Regulation of P-glycoprotein in Different Tissues and Organs., PMID:40331390
Novel dihydrochalcone from Fissistigma latifolium targets STAT3 and survivin to overcome multidrug resistance cancers in vitro and in vivo., PMID:40327991
St. John's Wort Extract Increases Pgp Expression in the Brain but Not in the Small Intestine or the Liver of Wistar Rats., PMID:40325522
Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein., PMID:40308775
Structural and Distribution Analysis of Mechanoreceptors and Free Nerve Endings in the Annular Pulleys of the Flexor Tendons of the Hand., PMID:40304069
DBP degradation and PGPR-mediated enhancement: Mechanisms of Enterobacter sp. X1 revealed by maize (Zea mays L.) transcriptome and rhizosphere microbiome analysis., PMID:40300371
Sucralose Promotes Benzo(a)Pyrene-Induced Renal Toxicity in Mice by Regulating P-glycoprotein., PMID:40298799
Structure characterization and protective effect against UVB irradiation of polysaccharides isolated from the peach gums., PMID:40294685
For research use only. Not for human or drug use.
