Catalog No.
YHN50601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser148-Asp335
Predicted molecular weight
24.02 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A2RU30
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein TESPA1, Thymocyte-expressed positive selection-associated protein 1, TESPA1, KIAA0748, HSPC257
The IP3 receptor-KRAP complex at the desmosomes: A new player in the apoptotic process., PMID:39447342
Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer., PMID:38012143
Tespa1 deficiency reduces the antitumour immune response by decreasing CD8+T cell activity in a mouse Lewis lung cancer model., PMID:37660596
Tespa1 facilitates hematopoietic and leukemic stem cell maintenance by restricting c-Myc degradation., PMID:36997676
Analysis of Systemic Epigenetic Alterations in Inflammatory Bowel Disease: Defining Geographical, Genetic and Immune-Inflammatory influences on the Circulating Methylome., PMID:36029471
Alcohol use disorder is associated with DNA methylation-based shortening of telomere length and regulated by TESPA1: implications for aging., PMID:35705636
A CD8+ T Cell-Related Genes Expression Signature Predicts Prognosis and the Efficacy of Immunotherapy in Breast Cancer., PMID:35088220
Transcriptome Analysis of lncRNA-mRNA Interactions in Chronic Atrophic Gastritis., PMID:33505433
Tespa1 plays a role in the modulation of airway hyperreactivity through the IL-4/STAT6 pathway., PMID:33228696
Thymocyte selection: From signaling to epigenetic regulation., PMID:31699214
New Insights in the IP3 Receptor and Its Regulation., PMID:31646513
Thymic-specific regulation of TCR signaling by Tespa1., PMID:31316154
Tespa1 Deficiency Dampens Thymus-Dependent B-Cell Activation and Attenuates Collagen-Induced Arthritis in Mice., PMID:29867947
Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors., PMID:28598420
Tespa1 is associated with susceptibility but not severity of rheumatoid arthritis in the Zhejiang Han population in China., PMID:25736038
Tespa1 negatively regulates FcεRI-mediated signaling and the mast cell-mediated allergic response., PMID:25422497
Fine-tuning T cell receptor signaling to control T cell development., PMID:24951034
Lack of association between TESPA1 gene polymorphisms (rs1801876, rs2171497, rs4758994, and rs997173) and ankylosing spondylitis in a Chinese population., PMID:24893580
Tespa1 protein is phosphorylated in response to store-operated calcium entry., PMID:23541577
Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux., PMID:23501103
Tespa1: another gatekeeper for positive selection., PMID:22610243
Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling., PMID:22561606
Tespa1 is a novel inositol 1,4,5-trisphosphate receptor binding protein in T and B lymphocytes., PMID:23650607
For research use only. Not for human or drug use.
