Catalog No.
YHN49701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His23-Glu293
Predicted molecular weight
32.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BRK3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Matrix remodeling-associated protein 8, Limitrin, MXRA8
Associations of 2923 plasma proteins with incident inflammatory bowel disease in a prospective cohort study and genetic analysis., PMID:40118817
Distinct cellular and molecular responses to infection in three target cell types from horses, a species naturally susceptible to Ross River virus., PMID:40010657
Plasma Proteomic Signatures of Physical Activity Provide Insights into Biological Impacts of Physical Activity and its Protective Role Against Dementia., PMID:39867359
Changes in the chikungunya virus E1 glycoprotein domain II and hinge influence E2 conformation, infectivity, and virus-receptor interactions., PMID:38842335
Evolutionary Profile of Mayaro Virus in the Americas: An Update into Genome Variability., PMID:38793690
Single-cell RNA combined with bulk RNA analysis to explore oxidative stress and energy metabolism factors and found a new prostate cancer oncogene MXRA8., PMID:38441550
Plasma proteomic profile of abdominal obesity in older adults., PMID:38439214
The chikungunya virus E1 glycoprotein fusion loop and hinge alter glycoprotein dynamics leading to cell and host specific changes in infectivity., PMID:37961096
Insights from the molecular docking analysis of gambogic acid with the Chikungunya spike glycoprotein E2., PMID:37886138
STT3A-mediated viral N-glycosylation underlies the tumor selectivity of oncolytic virus M1., PMID:37864032
Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8., PMID:37804831
Loss of MXRA8 Delays Mammary Tumor Development and Impairs Metastasis., PMID:37762032
Chikungunya virus cell-to-cell transmission is mediated by intercellular extensions in vitro and in vivo., PMID:37591996
Role of MXRA8 in Ross River Virus Disease Pathogenesis., PMID:37036079
The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito., PMID:37018377
Basigin is necessary for normal decidualization of human uterine stromal cells., PMID:36303457
Complex effects of Mg-biomaterials on the osteoblast cell machinery: A proteomic study., PMID:35929259
Enhancer-promoter interaction maps provide insights into skeletal muscle-related traits in pig genome., PMID:35681201
Elevated Expression of miR-200c/141 in MDA-MB-231 Cells Suppresses MXRA8 Levels and Impairs Breast Cancer Growth and Metastasis In Vivo., PMID:35456497
Identification of the receptor of oncolytic virus M1 as a therapeutic predictor for multiple solid tumors., PMID:35393389
Matrix Remodeling-Associated Protein 8 as a Novel Indicator Contributing to Glioma Immune Response by Regulating Ferroptosis., PMID:35281049
In silico identification of small molecule protein-protein interaction inhibitors: targeting hotspot regions at the interface of MXRA8 and CHIKV envelope protein., PMID:35272566
[Bioinformatics analysis of differently expressed genes in osteoblastic sarcoma and screening of key genes]., PMID:35184458
Seven Genes Associated With Lymphatic Metastasis in Thyroid Cancer That Is Linked to Tumor Immune Cell Infiltration., PMID:35141140
A Population of CD4+CD8+ Double-Positive T Cells Associated with Risk of Plasma Leakage in Dengue Viral Infection., PMID:35062294
Matrix remodeling-associated protein 8 is a marker of a subset of cancer-associated fibroblasts in pancreatic cancer., PMID:35020975
Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor., PMID:34646020
Protective Role of Limitrin in Experimental Autoimmune Optic Neuritis., PMID:34232258
Single-cell RNA sequencing of human femoral head in vivo., PMID:34111027
BHK-21 Cell Clones Differ in Chikungunya Virus Infection and MXRA8 Receptor Expression., PMID:34063936
Cryo-EM structure of the mature and infective Mayaro virus at 4.4 Å resolution reveals features of arthritogenic alphaviruses., PMID:34031424
The CD147 Protein Complex Is Involved in Entry of Chikungunya Virus and Related Alphaviruses in Human Cells., PMID:33717005
Exploration of small-molecule entry disruptors for chikungunya virus by targeting matrix remodelling associated protein., PMID:33088330
Structural basis of Chikungunya virus inhibition by monoclonal antibodies., PMID:33087569
Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site., PMID:32783883
Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease., PMID:32365139
An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis., PMID:32075743
Mining TCGA database for screening and identification of hub genes in kidney renal clear cell carcinoma microenvironment., PMID:31697440
Expression of the Mxra8 Receptor Promotes Alphavirus Infection and Pathogenesis in Mice and Drosophila., PMID:31484075
Dermal and muscle fibroblasts and skeletal myofibers survive chikungunya virus infection and harbor persistent RNA., PMID:31465513
Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein., PMID:31080063
Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor., PMID:31080061
Mxra8 is a receptor for multiple arthritogenic alphaviruses., PMID:29769725
Tumor vessel up-regulation of INSR revealed by single-cell expression analysis of the tyrosine kinome and phosphatome in human cancers., PMID:25864925
Muscle gene expression associated with increased marbling in beef cattle., PMID:21500107
Limitin, an interferon-like cytokine, transduces inhibitory signals on B-cell growth through activation of Tyk2, but not Stat1, followed by induction and nuclear translocation of Daxx., PMID:14662340
Limitrin, a novel immunoglobulin superfamily protein localized to glia limitans formed by astrocyte endfeet., PMID:14603461
For research use only. Not for human or drug use.
