Catalog No.
YHN49201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala25-Lys116
Predicted molecular weight
23.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96DA6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DNAJC19, DnaJ homolog subfamily C member 19, TIM14, TIMM14, Mitochondrial import inner membrane translocase subunit TIM14
Mitochondrial proteins as therapeutic targets in diabetic ketoacidosis: evidence from Mendelian randomization analysis., PMID:39469619
Generation of a homozygous DNAJC19 knockout human embryonic stem cell line by CRISPR/Cas9 system., PMID:38696852
Mutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes., PMID:38142971
Anisomycin inhibits the activity of human ovarian cancer stem cells via regulating antisense RNA NCBP2-AS2/MEK/ERK/STAT3 signaling., PMID:37483091
Identification of novel biomarkers for lung squamous cell carcinoma., PMID:36742449
Novel homozygous pathogenic mitochondrial DNAJC19 variant in a patient with dilated cardiomyopathy and global developmental delay., PMID:35611801
Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes., PMID:35417719
Mitochondrial Protein Homeostasis and Cardiomyopathy., PMID:35328774
Multiple variants of the human presequence translocase motor subunit Magmas govern the mitochondrial import., PMID:34715125
Phenotype and pathology of the dilated cardiomyopathy with ataxia syndrome in children., PMID:34580891
Targeting DNAJC19 overcomes tumor growth and lung metastasis in NSCLC by regulating PI3K/AKT signaling., PMID:34217321
Reversible Mitochondrial Fragmentation in iPSC-Derived Cardiomyocytes From Children With DCMA, a Mitochondrial Cardiomyopathy., PMID:32046906
SS-31 Peptide Reverses the Mitochondrial Fragmentation Present in Fibroblasts From Patients With DCMA, a Mitochondrial Cardiomyopathy., PMID:31803760
Underappreciated Roles of the Translocase of the Outer and Inner Mitochondrial Membrane Protein Complexes in Human Disease., PMID:30481057
Genetic Basis of Severe Childhood-Onset Cardiomyopathies., PMID:30384889
HTRA2 Defect: A Recognizable Inborn Error of Metabolism with 3-Methylglutaconic Aciduria as Discriminating Feature Characterized by Neonatal Movement Disorder and Epilepsy-Report of 11 Patients., PMID:30114719
Previously Unreported Biallelic Mutation in DNAJC19: Are Sensorineural Hearing Loss and Basal Ganglia Lesions Additional Features of Dilated Cardiomyopathy and Ataxia (DCMA) Syndrome?, PMID:27928778
Mitochondrial hepato-encephalopathy due to deficiency of QIL1/MIC13 (C19orf70), a MICOS complex subunit., PMID:27485409
Progressive Cerebellar Atrophy and a Novel Homozygous Pathogenic DNAJC19 Variant as a Cause of Dilated Cardiomyopathy Ataxia Syndrome., PMID:27426421
Functional Diversity of Human Mitochondrial J-proteins Is Independent of Their Association with the Inner Membrane Presequence Translocase., PMID:27330077
Expanding the clinical, allelic, and locus heterogeneity of retinal dystrophies., PMID:26355662
Fine mapping and evolution of the major sex determining region in turbot (Scophthalmus maximus)., PMID:25106948
DNAJC19, a mitochondrial cochaperone associated with cardiomyopathy, forms a complex with prohibitins to regulate cardiolipin remodeling., PMID:24856930
Unraveling the intricate organization of mammalian mitochondrial presequence translocases: existence of multiple translocases for maintenance of mitochondrial function., PMID:24636990
Exome sequencing identifies a new mutation in SERAC1 in a patient with 3-methylglutaconic aciduria., PMID:23707711
Inborn errors of metabolism with 3-methylglutaconic aciduria as discriminative feature: proper classification and nomenclature., PMID:23296368
Brain region-specific altered expression and association of mitochondria-related genes in autism., PMID:23116158
New mutation of mitochondrial DNAJC19 causing dilated and noncompaction cardiomyopathy, anemia, ataxia, and male genital anomalies., PMID:22797137
Role of Magmas in protein transport and human mitochondria biogenesis., PMID:20053669
Cardiac features of a novel autosomal recessive dilated cardiomyopathic syndrome due to defective importation of mitochondrial protein., PMID:17244376
Mutation of DNAJC19, a human homologue of yeast inner mitochondrial membrane co-chaperones, causes DCMA syndrome, a novel autosomal recessive Barth syndrome-like condition., PMID:16055927
For research use only. Not for human or drug use.
