Catalog No.
YHN49001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser92-Gly172
Predicted molecular weight
21.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A8MYZ6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Forkhead box protein O6, FOXO6
FOXOs and their roles in acute and chronic neurological disorders., PMID:40260403
FOXO6: A unique transcription factor in disease regulation and therapeutic potential., PMID:40058512
Astragalin relieves inflammatory pain and negative mood in CFA mice by down-regulating mGluR5 signaling pathway., PMID:39962225
Disulfiram/Cu targeting FOXO6 modulates sensitivity of hepatocellular carcinoma to lenvatinib via disrupt choline metabolic., PMID:39694126
Immunocytochemistry-Based Detection of FOXO Isoforms in Human Cancer and Fibroblasts., PMID:39565588
Measuring FOXO Activity by Using qPCR-Based Expression Analysis of FOXO Target Genes., PMID:39565576
FOXO Transcription Factors: A Brief Overview., PMID:39565573
FoxO1 signaling in B cell malignancies and its therapeutic targeting., PMID:39533662
Bifidobacterium lactis-Derived Vesicles Attenuate Hippocampal Neuroinflammation by Targeting IL-33 to Regulate FoxO6/P53 Signaling., PMID:39519420
Modelling quiescence exit of neural stem cells reveals a FOXG1-FOXO6 axis., PMID:39499086
Hederagenin regulates the migration and invasion of hepatocellular carcinoma cells through FOXO signaling pathway., PMID:39383136
Betaine Suppresses Lipid Accumulation in Liver: Inhibition of FoxO6 and PPARγ Interaction., PMID:39263959
Endoplasmic reticulum stress induces hepatic steatosis through interaction between PPARα and FoxO6 in vivo and in vitro., PMID:39198274
FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in aged rats fed a high-fat diet., PMID:38441531
FoxO6-Mediated TXNIP Induces Lipid Accumulation in the Liver through NLRP3 Inflammasome Activation., PMID:38417829
Diverse WGBS profiles of longissimus dorsi muscle in Hainan black goats and hybrid goats., PMID:38097986
Qiteng Xiaozhuo granules medicated serum inhibits excessive proliferation and promotes apoptosis of human glomerular mesangial cells by targeting fat mass and obesity associated proteins., PMID:37946469
Emerging links between FOXOs and diabetic complications., PMID:37838103
Overexpression of FTO inhibits excessive proliferation and promotes the apoptosis of human glomerular mesangial cells by alleviating FOXO6 m6A modification via YTHDF3-dependent mechanisms., PMID:37822879
Forkhead box O6 (FoxO6) promotes cardiac pathological remodeling and dysfunction by activating Kif15-TGF-β1 under aggravated afterload., PMID:37799807
FOXO transcription factors as mediators of stress adaptation., PMID:37710009
Identification of multidrug chemoresistant genes in head and neck squamous cell carcinoma cells., PMID:37667354
Developmental dynamics of the single nucleus regulatory landscape of pig hippocampus., PMID:37428306
The discrete roles of individual FOXO transcription factor family members in B-cell malignancies., PMID:37275916
Metformin alleviates the cognitive impairment induced by benzo[a]pyrene via glucolipid metabolism regulated by FTO/FoxO6 pathway in mice., PMID:37133670
Homology Modeling, Screening, and Identification of Potential FOXO6 Inhibitors Curtail Gastric Cancer Progression: an In Silico Drug Repurposing Approach., PMID:37086375
Observation of increased levels of autophagy-related genes and proteins in women with preeclampsia: a clinical study., PMID:37039997
FOXO6 transcription inhibition of CTRP3 promotes OGD/R-triggered cardiac microvascular endothelial barrier disruption via SIRT1/Nrf2 signalling., PMID:36688407
The Pan-Cancer Multi-Omics Landscape of FOXO Family Relevant to Clinical Outcome and Drug Resistance., PMID:36555288
[Research progress on the role of FOXOs family in cancer]., PMID:36319107
FOXO transcription factors as therapeutic targets in human diseases., PMID:36280450
Biphenotypic Sinonasal Sarcoma with a Novel PAX3::FOXO6 Fusion: A Case Report and Review of the Literature., PMID:36169791
Transcriptomic comparison of ovarian granulosa cells between adult sheep and prepubertal lambs., PMID:35189817
[Expressions of FOXO1/3a/4/6 in human testis and their roles in testicular aging]., PMID:37462482
Knockdown of long non-coding MIR210HG inhibits cell proliferation, migration, and invasion in hepatoblastoma via the microRNA-608-FOXO6 axis., PMID:34918962
FOXOs: masters of the equilibrium., PMID:34610198
Upregulation of FoxO6 in nucleus pulposus cells promotes DNA damage repair via activation of RAD51., PMID:34533813
LncRNA HOXC-AS1 promotes nasopharyngeal carcinoma (NPC) progression by sponging miR-4651 and subsequently upregulating FOXO6., PMID:34507637
Association of genetic variants of FBXO32 and FOXO6 in the FOXO pathway with breast cancer risk., PMID:34197655
Role of Forkhead Box O Proteins in Hepatocellular Carcinoma Biology and Progression (Review)., PMID:34123834
Protease-activated receptor 2 induces ROS-mediated inflammation through Akt-mediated NF-κB and FoxO6 modulation during skin photoaging., PMID:34082382
Role and mechanism underlying FoxO6 in skeletal muscle in vitro and in vivo., PMID:34080654
Upregulation of deubiquitinase USP7 by transcription factor FOXO6 promotes EC progression via targeting the JMJD3/CLU axis., PMID:33768140
EIF2AK2 selectively regulates the gene transcription in immune response and histones associated with systemic lupus erythematosus., PMID:33588244
Control of preadipocyte proliferation, apoptosis and early adipogenesis by the forkhead transcription factor FoxO6., PMID:33290791
Downregulation of FOXO6 alleviates hypoxia-induced apoptosis and oxidative stress in cardiomyocytes by enhancing Nrf2 activation via upregulation of SIRT6., PMID:33123950
Enterotoxigenic Escherichia coli infection promotes enteric defensin expression via FOXO6-METTL3-m6A-GPR161 signalling axis., PMID:32914682
Antibiotic Treatment Prior to Injury Improves Post-Traumatic Osteoarthritis Outcomes in Mice., PMID:32899361
FoxO6 inhibits melanogenesis partly by elevating intracellular antioxidant capacity., PMID:32863230
Interaction between CHOP and FoxO6 promotes hepatic lipid accumulation., PMID:32639626
For research use only. Not for human or drug use.
