Catalog No.
YHN16001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys1319-Val1407
Predicted molecular weight
37.89 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96RT1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Erbin, Densin-180-like protein, Erbb2-interacting protein, Protein LAP2, ERBIN, ERBB2IP, KIAA1225, LAP2
Erbin interacts with NHERF1 and Ezrin to stabilize a membrane ErbB2 signaling complex in HER2-positive breast cancer., PMID:40390040
Research progress on sepsis-associated encephalopathy by inhibiting pyroptosis., PMID:40355013
Erbin Inhibited Angiogenesis in Vitro with the Inhibition on the STAT3 Pathway in Breast Cancer Cells., PMID:40277066
Erbin Regulates Tissue Factors Through Ras/Raf Pathway in Coagulation Disorders in Sepsis., PMID:39931168
Assessing the Causal Effect of Circulating Protein-To-Protein Ratio on the Risk of Morbidity of Hepatocellular Carcinoma., PMID:39778021
PSA Density and Lesion Volume: Key Factors in Avoiding Unnecessary Biopsies for PI-RADS 3 Lesions., PMID:39674908
VCPIP1 negatively regulates NF-κB signaling pathways by deubiquitinating and stabilizing Erbin in MDP-stimulated macrophages., PMID:39550842
NoxO1 regulates EGFR signaling by its interaction with Erbin., PMID:39426288
Erbin: an important therapeutic target for blocking tumor metastasis., PMID:39391694
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
Erbin alleviates sepsis-induced cardiomyopathy by inhibiting RIPK1-dependent necroptosis through activating PKA/CREB pathway., PMID:39216682
Endosomal catabolism of phosphatidylinositol 4,5-bisphosphate is fundamental in building resilience against pathogens., PMID:39087719
CRISPR-Cas9 library screening combined with an exosome-targeted delivery system addresses tumorigenesis/TMZ resistance in the mesenchymal subtype of glioblastoma., PMID:38773970
Targeting Erbin-mitochondria axis in platelets/megakaryocytes promotes B cell-mediated antitumor immunity., PMID:38232736
Erbin accelerates TFEB-mediated lysosome biogenesis and autophagy and alleviates sepsis-induced inflammatory responses and organ injuries., PMID:38105228
The Integration of Genome-Wide DNA Methylation and Transcriptomics Identifies the Potential Genes That Regulate the Development of Skeletal Muscles in Ducks., PMID:37895154
Evaluating the Oncological and Functional Outcomes in 167 Patients Undergoing Laparoscopic Radical Prostatectomy: Could Laparoscopy Still be a Viable Option in Suitable Patients?, PMID:37751192
ERBIN and phosphoglucomutase 3 deficiency., PMID:37369151
Knockout of Erbin promotes pyroptosis via regulating NLRP3/caspase-1/Gasdermin D pathway in sepsis-induced acute kidney injury., PMID:37310569
Exosomal ERBB2IP contributes to tumor growth via elevating PSAT1 expression in non-small cell lung carcinoma., PMID:37192746
Imbalance of NRG1-ERBB2/3 signalling underlies altered myelination in Charcot-Marie-Tooth disease 4H., PMID:36314052
Erbin protects against sepsis-associated encephalopathy by attenuating microglia pyroptosis via IRE1α/Xbp1s-Ca2+ axis., PMID:36171629
The synergistic effects of testosterone and phophodiesterase-5 inhibitor combination on oxidative stress markers, matrix metalloproteinases and oxidative DNA damage: A randomized controlled experimental study., PMID:35115255
Targeted IL-4Rα blockade ameliorates refractory allergic eosinophilic inflammation in a patient with dysregulated TGF-β signaling due to ERBIN deficiency., PMID:35093604
A novel lncRNA-miRNA-mRNA competing endogenous RNA regulatory network in lung adenocarcinoma and kidney renal papillary cell carcinoma., PMID:34453499
RASGRF2 gene fusions identified in a variety of melanocytic lesions with distinct morphological features., PMID:34310073
Sorting of cadherin-catenin-associated proteins into individual clusters., PMID:34272290
Comprehensive Assessment of the Relationship Between Site-2 Specificity and Helix α2 in the Erbin PDZ Domain., PMID:34171344
The diagnostic role of testicular fatty acid-binding protein in testicular ischemia: A randomized controlled experimental study., PMID:33818429
Targeting Erbin in B cells for therapy of lung metastasis of colorectal cancer., PMID:33707428
Extracellular Vesicles From Liver Progenitor Cells Downregulates Fibroblast Metabolic Activity and Increase the Expression of Immune-Response Related Molecules., PMID:33511119
Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer., PMID:33482911
The circular RNA circ-ERBIN promotes growth and metastasis of colorectal cancer by miR-125a-5p and miR-138-5p/4EBP-1 mediated cap-independent HIF-1α translation., PMID:33225938
Comprehensive Analysis of RNA-Seq Gene Expression Profiling of Brain Transcriptomes Reveals Novel Genes, Regulators, and Pathways in Autism Spectrum Disorder., PMID:33080834
The Scribble family in cancer: twentieth anniversary., PMID:32999444
Reduced IκBα promotes hepatocellular carcinoma cell proliferation and migration via regulation of NF-κB/Erbin axis., PMID:32963622
Transcriptomic profiling revealed key signaling pathways for cold tolerance and acclimation of two carp species., PMID:32758130
The leucine-rich repeat signaling scaffolds Shoc2 and Erbin: cellular mechanism and role in disease., PMID:32558243
An Erbin Story: Amygdala Excitation-Inhibition Balance in Anxiety., PMID:32381157
Erbin in Amygdala Parvalbumin-Positive Neurons Modulates Anxiety-like Behaviors., PMID:31889536
Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities., PMID:31654425
Effect of endothelial dysfunction on the pathogenesis of urolithiasis in patients with metabolic syndrome., PMID:31596163
Comparison of Miniaturized Percutaneous Nephrolithotomy and Standard Percutaneous Nephrolithotomy in Secondary Patients: A Randomized Prospective Study., PMID:31537115
New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD., PMID:31286804
MicroRNA-148a-3p promotes survival and migration of endothelial cells isolated from Apoe deficient mice through restricting circular RNA 0003575., PMID:31255737
Scribble, Erbin, and Lano redundantly regulate epithelial polarity and apical adhesion complex., PMID:31147384
Ischemia Modified Albumin and D-dimer in the Diagnosis of Testicular Torsion: An Experimental Model., PMID:31119719
A Multireporter Bacterial 2-Hybrid Assay for the High-Throughput and Dynamic Assay of PDZ Domain-Peptide Interactions., PMID:30969105
miR-183-5p Inhibits Occurrence and Progression of Acute Myeloid Leukemia via Targeting Erbin., PMID:30799283
Desmoglein 1 Regulates Invadopodia by Suppressing EGFR/Erk Signaling in an Erbin-Dependent Manner., PMID:30655320
For research use only. Not for human or drug use.
