Catalog No.
YHG38401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser7-Arg101
Predicted molecular weight
24.20 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13049
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
E3 ubiquitin-protein ligase TRIM32, 2.3.2.27, 72 kDa Tat-interacting protein, RING-type E3 ubiquitin transferase TRIM32, Tripartite motif-containing protein 32, Zinc finger protein HT2A, TRIM32, HT2A
Inhibitory Effect and Mechanism of the Down-Regulation of TRIM32 in Colorectal Cancer., PMID:40507857
LINC00265 Serves as a Diagnostic and Prognostic Marker for Acute Ischemic Stroke and INHIBITS Disease Progression Through the miR- 155 - 5p/TRIM32 Axis., PMID:40317416
Latest News from the "Guardian": p53 Directly Activates Asymmetric Stem Cell Division Regulators., PMID:40243948
TRIM32 positively regulates c-di-GMP-Induced type I interferon signaling pathway in Listeria monocytogenes infection., PMID:40049511
Investigating genotype-phenotype correlation of limb-girdle muscular dystrophy R8: association of clinical severity, protein biological function and protein oligomerization., PMID:40038764
The Trim32-DPEP2 axis is an inflammatory switch in macrophages during intestinal inflammation., PMID:40021897
The TRIM32 geno-phenotype spectrum: a literature review and 25-year clinical follow-up of two brothers living with sarcotubular myopathy., PMID:40017290
TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4., PMID:39897031
Acetylation-ubiquitination crosstalk of DJ-1 mediates microcalcification formation in diabetic plaques via collagen-matrix vesicles interaction., PMID:39786474
DNA-damage orchestrates self-renewal and differentiation via reciprocal p53 family and Hippo/Wnt/TGF-β pathway activation in embryonic stem cells., PMID:39762370
TRIM32 regulates insulin sensitivity by controlling insulin receptor degradation in the liver., PMID:39747658
Tripartite motif-containing 32 regulated by miR-6236-p5 inhibited silica-induced apoptosis of alveolar macrophages., PMID:39742911
TRIM32 inhibits Venezuelan equine encephalitis virus infection by targeting a late step in viral entry., PMID:39527628
Mechanism of lactic acidemia-promoted pulmonary endothelial cells death in sepsis: role for CIRP-ZBP1-PANoptosis pathway., PMID:39465383
Opposing regulation of the STING pathway in hepatic stellate cells by NBR1 and p62 determines the progression of hepatocellular carcinoma., PMID:39423823
Role of AMBRA1 in mitophagy regulation: emerging evidence in aging-related diseases., PMID:39113560
Quercetin alleviates kidney damage caused by mercury Chloride: The protective effects of quercetin on autophagy and inflammation were studied based on TRIM32/TLR4/LC3 pathway., PMID:39033964
Molecular mechanism of TRIM32 in antiviral immunity in rainbow trout (Oncorhynchus mykiss)., PMID:39004296
Adipose stem cell‑derived exosomes promote high glucose-induced wound healing by regulating the TRIM32/STING axis., PMID:38822901
A host E3 ubiquitin ligase regulates Salmonella virulence by targeting an SPI-2 effector involved in SIF biogenesis., PMID:38817622
Degradation of TRIM32 is induced by RTA for Kaposi's sarcoma-associated herpesvirus lytic replication., PMID:38717113
Research on the Effect and Mechanism of Selenium on Colorectal Cancer Through TRIM32., PMID:38691306
Identification of inflammation-related biomarkers in keloids., PMID:38444850
Enhanced translocation of TRIM32 to mitochondria sensitizes dopaminergic neuronal cells to apoptosis during stress conditions in Parkinson's disease., PMID:38317520
Case report: A novel patient presenting TRIM32-related limb-girdle muscular dystrophy., PMID:38304327
Identification of genes related to growth from transcriptome profiles of the muscle and liver of Chinese longsnout catfish (Leiocassis longirostris)., PMID:38150989
TRIM32 Inhibits NEK7 Ubiquitylation-Dependent Microglia Pyroptosis After Spinal Cord Injury., PMID:38030945
RHBDF1 deficiency suppresses melanoma glycolysis and enhances efficacy of immunotherapy by facilitating glucose-6-phosphate isomerase degradation via TRIM32., PMID:37979663
The antiviral effects of TRIM23 and TRIM32 proteins in rainbow trout (Oncorhynchus mykiss)., PMID:37967780
ATM-CHK2-TRIM32 axis regulates ATG7 ubiquitination to initiate autophagy under oxidative stress., PMID:37943659
TRIMming down Mycobacterium tuberculosis replication: TRIM32 is required for bacterial ubiquitination and autophagy induction in macrophages., PMID:40395310
4E-BP1-dependent translation in nociceptors controls mechanical hypersensitivity via TRIM32/type I interferon signaling., PMID:37922363
CDK2-activated TRIM32 phosphorylation and nuclear translocation promotes radioresistance in triple-negative breast cancer., PMID:37734566
TRIM32 promotes oral squamous cell carcinoma progression by enhancing FBP2 ubiquitination and degradation., PMID:37640002
Tripartite Motif-Containing Protein 32 (TRIM32): What Does It Do for Skeletal Muscle?, PMID:37626915
Exosomes derived from Mouse Bone Marrow Mesenchymal Stem Cells Attenuate Nucleus Pulposus Cell Apoptosis via the miR-155- 5p/Trim32 Axis., PMID:37587825
The ubiquitin ligase TRIM32 promotes the autophagic response to Mycobacterium tuberculosis infection in macrophages., PMID:37543647
TSPAN18 facilitates bone metastasis of prostate cancer by protecting STIM1 from TRIM32-mediated ubiquitination., PMID:37542345
Mercuric chloride induced brain toxicity in mice: The protective effects of puerarin-loaded PLGA nanoparticles., PMID:37401655
TRIM32 biallelic defects cause limb-girdle muscular dystrophy R8: identification of two novel mutations and investigation of genotype-phenotype correlation., PMID:37217920
Glutamylation of an HIV-1 protein inhibits the immune response by hijacking STING., PMID:37099423
Tripartite motif-containing protein 32 regulates Ca2+ movement in skeletal muscle., PMID:36374170
Eight TRIM32 isoforms from oriental river prawn Macrobrachium nipponense are involved in innate immunity during white spot syndrome virus infection., PMID:36243272
Germline immortality relies on TRIM32-mediated turnover of a maternal mRNA activator in C. elegans., PMID:36240265
Overexpression of TRIM32 promotes pancreatic β-cell autophagic cell death through Akt/mTOR pathway under high glucose conditions., PMID:36040726
The Notch signaling pathway in skeletal muscle health and disease., PMID:35968817
Ubiquitination-coupled liquid phase separation regulates the accumulation of the TRIM family of ubiquitin ligases into cytoplasmic bodies., PMID:35930602
The E3 ligase Thin controls homeostatic plasticity through neurotransmitter release repression., PMID:35796533
Up-Regulation of TRIM32 Associated With the Poor Prognosis of Acute Myeloid Leukemia by Integrated Bioinformatics Analysis With External Validation., PMID:35756612
For research use only. Not for human or drug use.
