Catalog No.
YHE14601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu90-Lys187
Predicted molecular weight
25.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35659
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein DEK, DEK
DEK::AFF2-Associated Papillary Squamous Cell Carcinoma of the Sinonasal Tract: Clinicopathologic Characterization of 9 Cases., PMID:40392381
Primary Laryngeal Squamous Cell Carcinoma with DEK::AFF2 Fusion: The First Case Report., PMID:40299135
DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes., PMID:40204893
XPO1-dependency of DEK::NUP214 leukemia., PMID:40148556
Acute myeloid leukemia with DEK::NUP214 fusion resembling acute promyelocytic leukemia, initially presenting as sweet syndrome: A case report and literature review., PMID:40138481
Eupalinolide B targets DEK and PANoptosis through E3 ubiquitin ligases RNF149 and RNF170 to negatively regulate asthma., PMID:40120540
DEK::AFF2 rearranged neoplasm with undifferentiated morphology and neuroendocrine phenotype in a pediatric patient., PMID:40119902
Proto-oncogene DEK binds to pre-mRNAs and regulates the alternative splicing of Hippo signaling genes in HeLa cells., PMID:40075046
[Acupuncture inhibits epithelial mesenchymal transition in allergic asthma rats by activating the PI3K/AKT pathway through DEK activation]., PMID:40059051
Inhibition of DEK restores hematopoietic stem cell function in Fanconi anemia., PMID:39836085
An evolutionary dynamics analysis of the plant DEK gene family reveals the role of BnaA02g08940D in drought tolerance., PMID:39828179
DEK :: AFF2 Fusion Sinonasal and Skull Base Nonkeratinizing Squamous Cell Carcinoma : A Clinical Outcome Study Compared With Conventional Sinonasal Squamous Cell Carcinoma., PMID:39719672
DEK::AFF2 Carcinoma of the Sinonasal Tract and Skull Base: A Comprehensive Review., PMID:39489551
DEK regulates B-cell proliferative capacity and is associated with aggressive disease in low-grade B-cell lymphomas., PMID:39384745
DEK::AFF2 Fusion-Associated Squamous Cell Carcinoma: A Case Series with Literature Review on an Emerging and Challenging Entity., PMID:39312022
Engineered Enucleated Mesenchymal Stem Cells Regulating Immune Microenvironment and Promoting Wound Healing., PMID:39295480
Sinonasal Squamous Cell Carcinoma with DEK::AFF2 Rearrangement : An Aggressive Cancer with Bland Morphology., PMID:39132684
[High-risk acute myeloid leukemia with DEK-NUP214 rearrangement and eyelid infiltration: a case report]., PMID:38964929
[Analysis of therapeutic effects of allogeneic hematopoietic stem cell transplantation in 12 patients with DEK-NUP214 fusion gene positive acute myeloid leukemia]., PMID:38951067
DEK deficiency suppresses mitophagy to protect against house dust mite-induced asthma., PMID:38274803
Super-resolution microscopy reveals the nanoscale cluster architecture of the DEK protein cancer biomarker., PMID:38026229
Imaging-based study demonstrates how the DEK nanoscale distribution differentially correlates with epigenetic marks in a breast cancer model., PMID:37550322
The impact of the chromatin binding DEK protein in hematopoiesis and acute myeloid leukemia., PMID:37172756
Low-grade papillary Schneiderian carcinoma with TP53 mutation: a case report and review of the literature., PMID:37041626
[Analysis of 7 cases of pediatric acute myeloid leukemia with DEK-NUP214 fusion gene]., PMID:37011983
From ecology to oncology: To understand cancer stem cell dormancy, ask a Brine shrimp (Artemia)., PMID:36990533
The Effect of the Histone Chaperones HSPA8 and DEK on Tumor Immunity in Hepatocellular Carcinoma., PMID:36768989
Translocations and Gene Fusions in Sinonasal Malignancies., PMID:36753024
Addition of venetoclax to myeloablative conditioning regimens for allogeneic hematopoietic stem cell transplantation in high-risk AML., PMID:36629738
Stimulus-responsive and dual-target DNA nanodrugs for rheumatoid arthritis treatment., PMID:36572263
Role of DEK in carcinogenesis, diagnosis, prognosis, and therapeutic outcome of breast cancer: An evidence-based clinical review., PMID:36535490
Understanding a high-risk acute myeloid leukemia by analyzing the interactome of its major driver mutation., PMID:36288392
Novel molecular mechanisms in Alzheimer's disease: The potential role of DEK in disease pathogenesis., PMID:36275000
DEK::AFF2 Fusion Carcinomas of Head and Neck., PMID:36221219
Doxorubicin induces prolonged DNA damage signal in cells overexpressing DEK isoform-2., PMID:36190960
Deciphering the endometrial immune landscape of RIF during the window of implantation from cellular senescence by integrated bioinformatics analysis and machine learning., PMID:36131919
miR-181-5p attenuates neutrophilic inflammation in asthma by targeting DEK., PMID:36115279
IMMUNOEXPRESSION OF DEK AND PHOSPHO-P38 PROTEINS IN RECTAL CANCER BEFORE CHEMORADIATION THERAPY., PMID:36102441
NMR-based metabolomic analysis identifies RON-DEK-β-catenin dependent metabolic pathways and a gene signature that stratifies breast cancer patient survival., PMID:36067206
CD163 Immunohistochemical "Circle Sign" Staining Pattern Differentiates Sinonasal Papillomas From Morphologically Similar Non-neoplastic Lesions., PMID:35993580
In silico gene expression and pathway analysis of DEK in the human brain across the lifespan., PMID:35972263
Activation of signaling pathways in models of t(6;9)-acute myeloid leukemia., PMID:35941390
Protein DEK and DTA Aptamers: Insight Into the Interaction Mechanisms and the Computational Aptamer Design., PMID:35928230
p21-activated kinase 2 binds to transcription factor SOX2 and up-regulates DEK to promote the progression of lung squamous cell carcinoma., PMID:35821094
First Report of Thoracic Carcinoma With DEK::AFF2 Rearrangement: A Case Report., PMID:35773081
Inhibition of DEK Enhances Doxorubicin-Induced Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia Cells., PMID:35769815
Nuclear expression of AFF2 C-terminus is a sensitive and specific ancillary marker for DEK::AFF2 carcinoma of the sinonasal tract., PMID:35701667
Molecular Classification and Overcoming Therapy Resistance for Acute Myeloid Leukemia with Adverse Genetic Factors., PMID:35682627
Long Non-Coding LEF1-AS1 Sponge miR-5100 Regulates Apoptosis and Autophagy in Gastric Cancer Cells via the miR-5100/DEK/AMPK-mTOR Axis., PMID:35563178
DEK modulates both expression and alternative splicing of cancer‑related genes., PMID:35475534
For research use only. Not for human or drug use.
