Catalog No.
YHD78501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu236-Lys311
Predicted molecular weight
24.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P28335
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
5-hydroxytryptamine receptor 2C, 5-HT-2C, 5-HT2C, 5-HTR2C, 5-hydroxytryptamine receptor 1C, 5-HT-1C, 5-HT1C, Serotonin receptor 2C, HTR2C, HTR1C
A cell-type-specific epigenetic mechanism encodes social investigatory behavior via Lrhcn1 and Hcn1., PMID:40465726
Sexual dimorphism of lung immune-regulatory units imprint biased pulmonary fibrosis., PMID:40360692
Prenatal Intake of High Multivitamins or Folic Acid With or Without Choline Contributes to Gut Microbiota-Associated Dysregulation of Serotonin in Offspring., PMID:40123263
Exploring therapeutic potential of Bacopa monnieri bioactive compounds against Alzheimer's and Parkinson's diseases., PMID:39959708
Repurposing of dipeptidyl peptidase FDA-approved drugs in Alzheimer's disease using network pharmacology and in-silico approaches., PMID:39938415
Polysaccharides from Scrophularia ningpoensis Hemsl. improve reserpine-induced depression-like behavior by inhibiting HTR2A/HTR2C mediated AKT/GSK3β/β-catenin/CBP/BDNF signalling., PMID:39884598
Revealing the therapeutic targets, mechanisms, and heterogeneity of Huatan Jieyu Granules for Parkinson's disease through single-cell sequencing., PMID:39864142
Pharmacogenetic Testing in Treatment-resistant Panic Disorder: a Preliminary Analysis., PMID:39839219
The microRNA-29ab1/Zfp36/AR Axis in the Hypothalamus Regulates Male-Typical Behaviors in Mice., PMID:39684798
Exploring the potential pharmacological mechanism of aripiprazole against hyperprolactinemia based on network pharmacology and molecular docking., PMID:39511179
Neural circuits expressing the serotonin 2C receptor regulate memory in mice and humans., PMID:38941473
Social Isolation Induces Changes in the Monoaminergic Signalling in the Rat Medial Prefrontal Cortex., PMID:38920671
Therapeutic Strategies Against Metabolic Imbalance in a Male Mouse Model With 5-HT2CR Loss-of-Function., PMID:38815086
Mendelian Randomization Analysis Identifies Inverse Causal Relationship between External Eating and Metabolic Phenotypes., PMID:38674857
Association of serotonin receptor gene polymorphisms with anorexia nervosa: a systematic review and meta-analysis., PMID:38668826
Broiler Heart Muscle Monoaminergic Receptors Alteration in Response to Chronic Heat Stress: Based on Transcription Analysis., PMID:38590690
The polymorphisms of candidate pharmacokinetic and pharmacodynamic genes and their pharmacogenetic impacts on the effectiveness of risperidone maintenance therapy among Saudi children with autism., PMID:38421437
Biomarkers of Affective Dysregulation Associated with In Utero Exposure to EtOH., PMID:38201206
The N221D variant in PCSK1 is highly prevalent in childhood obesity and can influence the metabolic profile., PMID:37877373
Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre., PMID:37772438
Association of Serotonin Receptor Gene Polymorphisms with Regulatory and Adaptive Capacities of Medical Students., PMID:37768455
Turicibacter fermentation enhances the inhibitory effects of Antrodia camphorata supplementation on tumorigenic serotonin and Wnt pathways and promotes ROS-mediated apoptosis of Caco-2 cells., PMID:37663253
Long-term Impact of Prenatal Famine on Differential DNA Methylation of Genes in the Serotonin Receptor Signalling Pathway in Adults., PMID:37598834
Platelet Serotonin (5-HT) Concentration, Platelet Monoamine Oxidase B (MAO-B) Activity and HTR2A, HTR2C, and MAOB Gene Polymorphisms in Asthma., PMID:37238670
Serotonin modulates social responses to stressed conspecifics via insular 5-HT2C receptors in rat., PMID:37230216
Extract of Aster koraiensis Nakai Leaf Ameliorates Memory Dysfunction via Anti-inflammatory Action., PMID:36982837
Molecular targets of metformin against ovarian cancer based on network pharmacology., PMID:36977503
Trait sensitivity to negative feedback in rats is associated with increased expression of serotonin 5-HT2A receptors in the ventral hippocampus., PMID:36846570
Serotonin modulates social responses to stressed conspecifics via insular 5-HT 2C receptors in rat., PMID:36824837
Pharmacogenetics of anxiety and depression in Alzheimer's disease., PMID:36628952
Human loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior., PMID:36536256
Molecular neurobiological markers in the onset of sodium appetite., PMID:35987984
Social Fear Affects Limbic System Neuronal Activity and Gene Expression., PMID:35897794
Disrupted serotonin system development via early life antidepressant exposure impairs maternal care and increases serotonin receptor expression in adult female offspring., PMID:35748633
Adverse maternal environment affects hippocampal HTR2c variant expression and epigenetic characteristics in mouse offspring., PMID:35121849
Psoriasis and 5HT-R2C Gene Polymorphism: Association between Clinical, Demographic and Therapeutic Parameters in the Turkish Population., PMID:34990340
A zebrafish embryo screen utilizing gastrulation identifies the HTR2C inhibitor pizotifen as a suppressor of EMT-mediated metastasis., PMID:34919051
Conservation of A-to-I RNA editing in bowhead whale and pig., PMID:34882682
Gαi/o-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents., PMID:34788630
Melanocortin 4 receptor stimulation prevents antidepressant-associated weight gain in mice caused by long-term fluoxetine exposure., PMID:34673574
Monoaminergic Multilocus Genetic Variants Interact with Stressful Life Events in Predicting Changes in Adolescent Anxiety Symptoms: A One-year Longitudinal Study., PMID:34515911
X-linked serotonin 2C receptor is associated with a non-canonical pathway for sudden unexpected death in epilepsy., PMID:34396109
Central 5-HTR2C in the Control of Metabolic Homeostasis., PMID:34367066
Nucleoprotein (P40) Binding to 5HT2C Receptors (5HT2CR) is the Key Point in the Pathogenesis of BoDV-1-Infected Hosts., PMID:34165668
Clinical, Biochemical and Genetic Variables Associated With Metabolic Syndrome in Patients With Schizophrenia Spectrum Disorders Using Second-Generation Antipsychotics: A Systematic Review., PMID:33868046
Increasing Effects of Selective 5-Hydroxytryptamine Type 2C Receptor Stimulation on Evoked Momentary Urethral Closure in Female Rats and Humans., PMID:33837045
Evidence for Pharmacogenomic Effects on Risperidone Outcomes in Pediatrics., PMID:33759847
Effect of 5-HT2C receptor gene polymorphism (HTR2C-759C/T) on metabolic adverse effects in Thai psychiatric patients treated with risperidone., PMID:33683783
Functional constipation induces bladder overactivity associated with upregulations of Htr2 and Trpv2 pathways., PMID:33441874
Impact of polymorphisms in transporter and metabolizing enzyme genes on olanzapine pharmacokinetics and safety in healthy volunteers., PMID:33378980
For research use only. Not for human or drug use.
