Catalog No.
YHD15202
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser28-Gly351
Predicted molecular weight
38.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6PID9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Aggrecan core protein, Cartilage-specific proteoglycan core protein, ACAN
Transforming Properties of E6/E7 Oncogenes from Beta-2 HPV80 in Primary Human Fibroblasts., PMID:40508156
Novel PEI-aldehyde conjugates for gene delivery: Promoting chondrogenic differentiation in human mesenchymal stem cells., PMID:40487350
Molecular Mechanisms of Intervertebral Disc Degeneration: Significance of SPARC Gene Expression., PMID:40452200
Chondroitin sulfate/hyaluronic acid/carboxymethylcellulose macroporous cryogels for controlled delivery of TGF-β1 and IGF-1 to induce chondrogenic differentiation of adipose-derived stem cells in cartilage tissue engineering., PMID:40449777
The Characterization of Serum-Free Media on Human Mesenchymal Stem Cell Fibrochondrogenesis., PMID:40428164
Chondroitin sulfate reverses tibial dyschondroplasia, broiler chondrocyte proliferation and differentiation dysfunction via the CHST11/β-Catenin pathway., PMID:40409655
Bio-engineered thermo-sensitive alginate/PNIA-g-CS co-polymeric injectable hydrogel laden with GDF-5 to stimulate nucleus pulposus for IVD regeneration., PMID:40405200
Exosomes of Human Fetal Cartilage Progenitor Cells (hFCPCs) Inhibited Interleukin-1β (IL-1β)-Induced Osteoarthritis Phenotype via miR-125b-5p In Vitro., PMID:40372627
ATF1 and miR-27b-3p drive intervertebral disc degeneration through the PPARG/NF-κB signaling axis., PMID:40369110
Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration., PMID:40356987
Examining the Synergic Effect of Exosomes Derived from Mouse Mesenchymal Stem Cells and Low-frequency Electromagnetic Field on Chondrogenic Differentiation., PMID:40351083
OTX2 expression contributes progression of gastric cancer in young adults., PMID:40341176
Sirt6 deficiency promotes senescence and age-associated intervertebral disc degeneration in mice., PMID:40335469
Unveiling the mechanisms of mechanical loading-induced knee osteoarthritis through transcriptomics., PMID:40327988
Genome-wide association study and multi-ancestry meta-analysis identify common variants associated with carotid artery intima-media thickness., PMID:40321265
Effect of Plasminogen Activator Inhibitor-1 on extracellular matrix homeostasis in scaffold-free spheroids from human chondrocytes., PMID:40316399
Adipose-mesenchymal stem cells enhance the formation of auricular cartilage in vitro and in vivo., PMID:40304399
Effects of Oligomeric Proanthocyanidins on Cadmium-Induced Extracellular Matrix Damage via Inhibiting the ERK1/2 Signaling Pathway in Chicken Chondrocytes., PMID:40284819
Aggrecan immobilizes to perineuronal nets through hyaluronan-dependent and hyaluronan-independent binding activities., PMID:40273987
Loosening the Lid on Shoulder Osteoarthritis: How the Transcriptome and Metabolic Syndrome Correlate with End-Stage Disease., PMID:40243895
Comparison of tendon healing using local platelet-rich plasma, erythropoietin, and erythropoietin-bevacizumab in a rat Achilles tenotomy model., PMID:40235417
Irisin and its role in fracture healing: A comparative study with hyaluronic acid and platelet-rich plasma in a rat model., PMID:40235411
Enhanced cartilage repair using gelatin methacryloyl hydrogels combined with icariin and magnesium-doped bioactive glass., PMID:40235097
Synovial Fibroblast Extracellular Vesicles Induce Inflammation via Delivering miR-21-5p in Osteoarthritis., PMID:40214473
Effects of fluoxetine on the gene expression of hippocampus and gap inhibition in noise-induced hearing loss rats., PMID:40204224
Intermittent hypoxic stimulation promotes efficient expression of Hypoxia-inducible factor-1α and exerts a chondroprotective effect in an animal osteoarthritis model., PMID:40168275
Cartilage Intermediate Layer Protein-1 Promotes Extracellular Matrix Degeneration via Interacting With CD47., PMID:40122778
Selenium deficiency exacerbates cartilage degradation caused by HT-2 toxin via notch signaling pathway activation., PMID:40105990
Isolation, Characterization, and In Vitro Cell Studies of Plant-Based Exosome-like Nanovesicles for Treatment of Early Osteoarthritis., PMID:40076829
Unraveling the crucial role of SDF-1 in osteoarthritis progression: IL6/HIF-1α positive feedback and chondrocyte ferroptosis., PMID:40058106
Designing and cloning of fusion protein CpsA-CpsC-L-ACAN., PMID:39990539
MMP19 in vascular smooth muscle cells protects against thoracic aortic aneurysm and dissection via the MMP19/Aggrecan/Wnt/β-catenin axis., PMID:39954937
Pulsed electromagnetic field ameliorates the progression of osteoarthritis via the Sirt1/NF-κB pathway., PMID:39953605
LRP4 and Agrin Are Modulated by Cartilage Degeneration and Involved in β-Catenin Signaling in Human Articular Chondrocytes., PMID:39940775
Investigating the impact of Premolis semirufa caterpillar bristle toxins on human chondrocyte activation and inflammation., PMID:39928679
MLL4 regulates postnatal palate growth and midpalatal suture development., PMID:39925741
Extracellular baskets in inner hair cells and perineuronal nets in auditory nerves: Changes in noise-induced hearing loss rats., PMID:39922528
Dermal Fibroblast-Derived Exosomes Promotes Bone-to-Tendon Interface Healing of Chronic Rotator Cuff Tear in Rabbit Model., PMID:39914613
Changes in Gene Expression of the Extracellular Matrix in Patients with Full-Thickness Rotator Cuff Tears of Varying Sizes., PMID:39912080
A missense variant in the SOX5 gene (c.221C > T) is associated with intellectual disability., PMID:39905544
HDAC4 regulates apoptosis in Acan-CreERT2;HDAC4d /d mice with osteoarthritis by downregulating ATF4., PMID:39895575
Perturbations in plasma amino acid and lipoprotein subfraction profiles in anorexia nervosa before and after refeeding: A metabolomic cross-sectional and longitudinal analysis., PMID:39892164
Single-Cell Proteomics Uncovers Dual Traits of Dermal Sheath Cells in Wound Repair., PMID:39878130
Associations between skeletal muscle mass and elevated blood pressure are independent of body fat: a cross-sectional study in young adult women of African ancestry., PMID:39817427
Identification of selective sweep and associated QTL traits in Iranian Ovis aries and Ovis orientalis populations., PMID:39748948
Perineuronal Nets on CA2 Pyramidal Cells and Parvalbumin-Expressing Cells Differentially Regulate Hippocampal-Dependent Memory., PMID:39740999
The effect of exosomes from canine bone mesenchymal stem cells on IL-1β-mediated inflammatory responses in chondrocytes., PMID:39736844
Developmental gene expression in skull-base chordomas and chondrosarcomas., PMID:39690395
Patient-responsive protein biomarkers for cartilage degeneration and repair identified in the infrapatellar fat pad., PMID:39635821
Matrigel-encapsulated articular cartilage derived fibronectin adhesion assay derived chondroprogenitors for enhanced chondrogenic differentiation: An in vitro evaluation., PMID:39612596
For research use only. Not for human or drug use.
