Catalog No.
YHD09701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys253
Predicted molecular weight
30.93 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P15259
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Phosphoglycerate mutase 2, 5.4.2.11, 5.4.2.4, BPG-dependent PGAM 2, Muscle-specific phosphoglycerate mutase, Phosphoglycerate mutase isozyme M, PGAM-M, PGAM2, PGAMM
Hepatocellular carcinoma cells downregulate PGAM2 via SIRT2-mediated deacetylation modification to enhance aerobic glycolysis., PMID:40379975
Aerobic exercise acts differentially on proteins from glucose and glycogen pathways in the SOL and PL muscles of offspring rats submitted to a low-protein maternal diet., PMID:39954356
Transcriptomic Signature of Lipid Production in Australian Aurantiochytrium sp. TC20., PMID:39912956
Downregulation of PGAM2 alleviates angiotensin II-induced cardiac hypertrophy by destabilizing HSP90 and inactivating the mTOR/IKKα signaling pathway., PMID:39897023
Transcriptome Analysis Suggests PKD3 Regulates Proliferative Glucose Metabolism, Calcium Homeostasis and Microtubule Dynamics After MEF Spontaneous Immortalization., PMID:39859313
IDOL alleviates the body weight by upregulating UCP-1 in mice., PMID:39748219
Pyrroroquinoline Quinone (PQQ) Improves the Quality of Holstein Bull Semen during Cryopreservation., PMID:39457870
Unveiling therapeutic biomarkers and druggable targets in ALS: An integrative microarray analysis, molecular docking, and structural dynamic studies., PMID:39299050
Key genes and regulatory networks for diabetic retinopathy based on hypoxia-related genes: a bioinformatics analysis., PMID:39156775
Association of single nucleotide polymorphisms in Neuropeptide Y (NPY) and Phosphoglycerate Mutase 2 (PGAM2) genes with growth traits in rabbits., PMID:39133441
Investigation of single nucleotide polymorphisms in differentially expressed genes and proteins reveals the genetic basis of skeletal muscle growth differences between Tibetan and Large White pigs., PMID:38938033
Effect of cholesterol-loaded cyclodextrin treatment on boar sperm cryopreservation., PMID:38754842
Eicosapentaenoic acid-mediated activation of PGAM2 regulates skeletal muscle growth and development via the PI3K/AKT pathway., PMID:38641281
Targeting the Metabolic Enzyme PGAM2 Overcomes Enzalutamide Resistance in Castration-Resistant Prostate Cancer by Inhibiting BCL2 Signaling., PMID:37676279
Integrated analysis of transcriptome and proteome for exploring mechanism of promoting proliferation of equine satellite cells associated with leucine., PMID:37633218
A plasma proteomic approach in patients with heart failure after acute myocardial infarction: insights into the pathogenesis and progression of the disease., PMID:37265567
Towards the discovery of goat meat quality biomarkers using label-free proteomics., PMID:36871648
High-Resolution Crystal Structure of Muscle Phosphoglycerate Mutase Provides Insight into Its Nuclear Import and Role., PMID:36361985
Cloning of goat PGAM2 gene and its overexpression promotes the differentiation of intramuscular preadipocytes., PMID:36315243
Mitochondrial energy metabolic transcriptome profiles during cardiac differentiation from mouse and human pluripotent stem cells., PMID:36039736
Gill and Liver Transcript Expression Changes Associated With Gill Damage in Atlantic Salmon (Salmo salar)., PMID:35418993
Proteome basis for the biological variations in color and tenderness of longissimus thoracis muscle from beef cattle differing in growth rate and feeding regime., PMID:35227471
Genetic defects are common in myopathies with tubular aggregates., PMID:34908252
Therapeutic Role of Sirtuins Targeting Unfolded Protein Response, Coagulation, and Inflammation in Hypoxia-Induced Thrombosis., PMID:34803727
Kohonen Artificial Neural Network and Multivariate Analysis in the Identification of Proteome Changes during Early and Long Aging of Bovine Longissimus dorsi Muscle Using SWATH Mass Spectrometry., PMID:34523341
Physical exercise increases ROCK activity in the skeletal muscle of middle-aged rats., PMID:32032622
Proteomics analysis of asthenozoospermia and identification of glucose-6-phosphate isomerase as an important enzyme for sperm motility., PMID:31394311
Papillomavirus can be transmitted through the blood and produce infections in blood recipients: Evidence from two animal models., PMID:31340720
Metabolic Regulation of Glycolysis and AMP Activated Protein Kinase Pathways during Black Raspberry-Mediated Oral Cancer Chemoprevention., PMID:31336728
Novel significant stage-specific differentially expressed genes in hepatocellular carcinoma., PMID:31277598
Discovering Biomarkers and Pathways Shared by Alzheimer's Disease and Ischemic Stroke to Identify Novel Therapeutic Targets., PMID:31121943
The improved energy metabolism and blood oxygen-carrying capacity for pufferfish, Takifugu fasciatus, against acute hypoxia under the regulation of oxygen sensors., PMID:30225749
Pretreatment with cholesterol-loaded cyclodextrins prevents loss of motility associated proteins during cryopreservation of addra gazelle (Nanger dama ruficollis) spermatozoa., PMID:29458042
Diabetic Retinopathy and Laser Therapy in Rats: A Protein-Protein Interaction Network Analysis., PMID:29071030
Tumor Necrosis Factor Alpha and Insulin-Like Growth Factor 1 Induced Modifications of the Gene Expression Kinetics of Differentiating Skeletal Muscle Cells., PMID:26447881
Insulin/IGF1-PI3K-dependent nucleolar localization of a glycolytic enzyme--phosphoglycerate mutase 2, is necessary for proper structure of nucleolus and RNA synthesis., PMID:26033454
Oxidative stress activates SIRT2 to deacetylate and stimulate phosphoglycerate mutase., PMID:24786789
The zinc transporter, Slc39a7 (Zip7) is implicated in glycaemic control in skeletal muscle cells., PMID:24265765
[Cloning, expression and antigenicity analysis of phosphoglycerate mutase 2 gene of Toxoplasma gondii]., PMID:22908803
Proteomic analysis of effluents from perfused human heart for transplantation: identification of potential biomarkers for ischemic heart damage., PMID:22443514
CARM1/PRMT4 is necessary for the glycogen gene expression programme in skeletal muscle cells., PMID:22428544
The intestinal factor Tff3 and a miRNA network regulate murine caloric metabolism., PMID:21289491
Genomic profiling of messenger RNAs and microRNAs reveals potential mechanisms of TWEAK-induced skeletal muscle wasting in mice., PMID:20098732
Assignment and expression patterns of porcine muscle-specific isoform of phosphoglycerate mutase gene., PMID:18499067
Genomic analysis of five chromosome 7p deletion patients with Greig cephalopolysyndactyly syndrome (GCPS)., PMID:16829355
Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays., PMID:15199147
Mouse phosphoglycerate mutase M and B isozymes: cDNA cloning, enzyme activity assay and mapping., PMID:11250083
Molecular and cytogenetic analysis in two patients with microdeletions of 7p and Greig syndrome: hemizygosity for PGAM2 and TCRG genes., PMID:1981052
Developmental activation of phosphoglycerate mutase-2 in the testis of the mouse., PMID:2824255
For research use only. Not for human or drug use.
