Catalog No.
YHD03201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala17-Pro238
Predicted molecular weight
39.50 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P14138
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Endothelin-3, ET-3, Preproendothelin-3, PPET3, EDN3
Population genomic analysis identifies the complex structural variation at the fibromelanosis (FM) locus in chicken., PMID:40102581
Enteric neural crest development in Astyanax mexicanus surface fish and cavefish., PMID:40060476
EDNRB negatively regulates glycolysis to exhibit anti-tumor functions in prostate cancer by cGMP/PKG pathway., PMID:39788311
Lineage-specific intersection of endothelin and GDNF signaling in enteric nervous system development., PMID:39641974
Palmitoyl copper peptide and acetyl tyrosine complex enhances melanin production in both A375 and B16 cell lines., PMID:39632290
Identification of immune-related hub genes in spinal cord injury., PMID:39367463
Transcriptome-based screening and validation of key genes for wool color in cashmere goats., PMID:39259488
Endothelin 3/EDNRB signaling induces thermogenic differentiation of white adipose tissue., PMID:39174539
An endothelial regulatory module links blood pressure regulation with elite athletic performance., PMID:38885195
PAX3 haploinsufficiency in Maine Coon cats with dominant blue eyes and hearing loss resembling the human Waardenburg syndrome., PMID:38869246
Enhanced quality of hESC-derived melanocytes through modified concentration of endothelin-1., PMID:38284190
Important roles of Hif1a in maternal or adult BPA exposure induced pancreatic injuries., PMID:37460698
Decoding the fibromelanosis locus complex chromosomal rearrangement of black-bone chicken: genetic differentiation, selective sweeps and protein-coding changes in Kadaknath chicken., PMID:37424723
Comprehensive analysis of immune-related genes associated with the microenvironment of patients with unexplained infertility., PMID:36819496
Hub Genes and Immune Cell Infiltration in Hypoxia-Induced Pulmonary Hypertension: Bioinformatics Analysis and In Vivo Validation., PMID:36718060
Mandibulofacial dysostosis with alopecia results from ETAR gain-of-function mutations via allosteric effects on ligand binding., PMID:36637912
Endothelin-3 is epigenetically silenced in endometrioid endometrial cancer., PMID:36542159
A comprehensive genotype-phenotype evaluation of eight Chinese probands with Waardenburg syndrome., PMID:36329483
An integrative analysis of DNA methylation and gene expression to predict lung adenocarcinoma prognosis., PMID:36105089
Fibroblast morphology, growth rate and gene expression in facial melasma., PMID:35840442
Endothelin system expression in the kidney following cisplatin-induced acute kidney injury in male and female mice., PMID:35704945
Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome., PMID:35568059
Large-scale isolation of functional dermal papilla cells using novel surface marker LEPTIN Receptor., PMID:35524584
Population Genomic Sequencing Delineates Global Landscape of Copy Number Variations that Drive Domestication and Breed Formation of in Chicken., PMID:35391799
Identification of Immune Cells and Key Genes associated with Alzheimer's Disease., PMID:34975305
Roles of Enteric Neural Stem Cell Niche and Enteric Nervous System Development in Hirschsprung Disease., PMID:34575824
The immunosuppressive role of Edn3 overexpression in the melanoma microenvironment., PMID:34288510
Genetic insights, disease mechanisms, and biological therapeutics for Waardenburg syndrome., PMID:33633356
miR‑27a‑3p regulates the inhibitory influence of endothelin 3 on the tumorigenesis of papillary thyroid cancer cells., PMID:33537832
Neuron-Glia Interaction in the Developing and Adult Enteric Nervous System., PMID:33396231
A Novel Spontaneous Mutation of the SOX10 Gene Associated with Waardenburg Syndrome Type II., PMID:32908492
Insights into Endothelin-3 and Multiple Sclerosis., PMID:32589590
The ratio of circulating endothelin-1 to endothelin-3 associated with TIMI risk and dynamic TIMI risk score in ST elevation acute myocardial infarction., PMID:32315546
HOTAIR Knockdown Decreased the Activity Wnt/β-Catenin Signaling Pathway and Increased the mRNA Levels of Its Negative Regulators in Hela Cells., PMID:31820855
The clinical and genetic research of Waardenburg syndrome type I and II in Chinese families., PMID:31812001
Ultrastable and Biofunctionalizable Conjugated Polymer Nanoparticles with Encapsulated Iron for Ferroptosis Assisted Chemodynamic Therapy., PMID:31613630
Growth factor and receptor malfunctions associated with human genetic deafness., PMID:31506927
Endothelins (EDN1, EDN2, EDN3) and their receptors (EDNRA, EDNRB, EDNRB2) in chickens: Functional analysis and tissue distribution., PMID:31351053
Role of JNK, MEK and adenylyl cyclase signalling in speed and directionality of enteric neural crest-derived cells., PMID:31306639
Association of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients., PMID:31167651
Aberrant Expression of Histamine-independent Pruritogenic Mediators in Keratinocytes may be Involved in the Pathogenesis of Prurigo Nodularis., PMID:30809683
Evolution of Endothelin signaling and diversification of adult pigment pattern in Danio fishes., PMID:30226839
News from the endothelin-3/EDNRB signaling pathway: Role during enteric nervous system development and involvement in neural crest-associated disorders., PMID:30171849
Molecular cloning and characterization of the endothelin 3 gene in black bone sheep., PMID:29988351
A potential regulatory region near the EDN3 gene may control both harness racing performance and coat color variation in horses., PMID:29845762
Methylation pattern variation between goats and rats during the onset of puberty., PMID:29577480
Mosaic genome evolution in a recent and rapid avian radiation., PMID:29085063
Current status of the role of endothelins in regulating ovarian follicular function: A review., PMID:28967452
Epilation induces hair and skin pigmentation through an EDN3/EDNRB-dependent regenerative response of melanocyte stem cells., PMID:28779103
SOX10 mutation causes Waardenburg syndrome associated with distinctive phenotypic features in an Iranian family: A clue for phenotype-directed genetic analysis., PMID:28390600
For research use only. Not for human or drug use.
