Catalog No.
YHC92501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
[Val38-Asn74] & [Asp232-Gly273]
Predicted molecular weight
24.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12235
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADP/ATP translocase 1, ADP,ATP carrier protein 1, ADP,ATP carrier protein, heart/skeletal muscle isoform T1, Adenine nucleotide translocator 1, ANT 1, Solute carrier family 25 member 4, SLC25A4, AAC1, ANT1
The Impact of Obesity on Autophagy in Human Adipose-Derived Mesenchymal Stromal Cells., PMID:40116436
Establishment of a prediction model and immune infiltration characteristics of atherosclerosis progression based on neutrophil extracellular traps-related genes., PMID:40053030
Sengers syndrome caused by biallelic TIMM29 variants and RNAi silencing in Drosophila orthologue recapitulates the human phenotype., PMID:40022150
Genome-wide DNA methylation and transcriptome sequencing analyses of lens tissue in an age-related mouse cataract model., PMID:39883715
CD147 mitochondria translocation induced airway remodeling in asthmatic mouse models by regulating M2 macrophage polarization via ANT1-mediated mitophagy., PMID:39740799
Exploring α-synuclein Interaction Partners and their Potential Clinical Implications for Parkinson's Disease., PMID:39560845
The Hcp2b of APEC induces mitochondrial damage in chicken DF-1 cells., PMID:39552458
Indirubin induces apoptosis in ovarian cancer cells via the mitochondrial pathway., PMID:39544767
Dual-Probe Activity-Based Protein Profiling Reveals Site-Specific Differences in Protein Binding of EGFR-Directed Drugs., PMID:39052621
Comprehensive transcriptomic analysis identifies SLC25A4 as a key predictor of prognosis in osteosarcoma., PMID:38957810
Human mitochondrial carriers of the SLC25 family function as monomers exchanging substrates with a ping-pong kinetic mechanism., PMID:38937634
Functional diversity among cardiolipin binding sites on the mitochondrial ADP/ATP carrier., PMID:38839991
Unveiling the link between lactate metabolism and rheumatoid arthritis through integration of bioinformatics and machine learning., PMID:38644410
TMT-labeled quantitative malonylome analysis on the longissimus dorsi muscle of Laiwu pigs reveals the role of ACOT7 in fat deposition., PMID:38395145
Dramatic genome-wide reprogramming of mRNA in hypometabolic muscle., PMID:38355035
Lyssavirus M protein degrades neuronal microtubules by reprogramming mitochondrial metabolism., PMID:38349129
Postnatal growth restriction alters myocardial mitochondrial energetics in mice., PMID:38180279
Transcriptome analysis reveals dysfunction of the endoplasmic reticulum protein processing in the sonic muscle of small yellow croaker (Larimichthys polyactis) following noise exposure., PMID:38154196
Identification of genes related to glucose metabolism and analysis of the immune characteristics in Alzheimer's disease., PMID:37619853
Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress., PMID:37565250
Loss of ANT1 Increases Fibrosis and Epithelial Cell Senescence in Idiopathic Pulmonary Fibrosis., PMID:37487137
Adenine nucleotide carrier protein dysfunction in human disease., PMID:37449547
Mitochondrial GSNOR Alleviates Cardiac Dysfunction via ANT1 Denitrosylation., PMID:37377022
Clinicopathological significance of unraveling mitochondrial pathway alterations in non-small-cell lung cancer., PMID:37310411
Human mitochondrial ADP/ATP carrier SLC25A4 operates with a ping-pong kinetic mechanism., PMID:37278158
Herpes Simplex Type 1 UL43 Multiple Membrane-Spanning Protein Increases Energy Metabolism in Host Cells through Interacting with ARL2., PMID:36429022
Differential Expression of lncRNA-miRNA-mRNA and Their Related Functional Networks in New-Onset Type 2 Diabetes Mellitus among Chinese Rural Adults., PMID:36360309
Urine proteomic signatures predicting the progression from premalignancy to malignant gastric cancer., PMID:36356476
Comprehensive Analysis and Validation of Solute Carrier Family 25 (SLC25) and Its Correlation with Immune Infiltration in Pan-Cancer., PMID:36254139
Mitochondrial energy metabolic transcriptome profiles during cardiac differentiation from mouse and human pluripotent stem cells., PMID:36039736
ANT1 overexpression models: Some similarities with facioscapulohumeral muscular dystrophy., PMID:36030628
Identification of ADP/ATP Translocase 1 as a Novel Glycoprotein and Its Association with Parkinson's Disease., PMID:35962937
Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice., PMID:35940554
The sphingosine kinase inhibitor SKI-V suppresses cervical cancer cell growth., PMID:35541904
Kearns-Sayre syndrome with rare imaging finding of SLC25A4 Mutation., PMID:35477912
Exposure to benzo(a)pyrene suppresses mitophagy via ANT1-PINK1-Parkin pathway in ovarian corpus luteum during early pregnancy., PMID:34986425
Proteomic Identification of the SLC25A46 Interactome in Transgenic Mice Expressing SLC25A46-FLAG., PMID:34983179
Modulation and Pharmacology of the Mitochondrial Permeability Transition: A Journey from F-ATP Synthase to ANT., PMID:34770872
Conformational change of adenine nucleotide translocase-1 mediates cisplatin resistance induced by EBV-LMP1., PMID:34755470
RBFOX2 is critical for maintaining alternative polyadenylation patterns and mitochondrial health in rat myoblasts., PMID:34731606
Mitochondrial DNA depletion syndrome with a mutation in SLC25A4 developing epileptic encephalopathy: A case report., PMID:34452803
Site-specific acetylation of adenine nucleotide translocase 1 at lysine 23 in human muscle., PMID:34332952
Down-regulation of BCL2L13 renders poor prognosis in clear cell and papillary renal cell carcinoma., PMID:34193180
Ischemia Injury induces mPTP opening by reducing Sirt3., PMID:34119577
A Yeast-Based Screening Unravels Potential Therapeutic Molecules for Mitochondrial Diseases Associated with Dominant ANT1 Mutations., PMID:33923309
ANT1 Activation and Inhibition Patterns Support the Fatty Acid Cycling Mechanism for Proton Transport., PMID:33801254
Mapping drug-target interactions and synergy in multi-molecular therapeutics for pressure-overload cardiac hypertrophy., PMID:33589646
Bufarenogin induces intrinsic apoptosis via Bax and ANT cooperation., PMID:33421322
Reduction of elevated proton leak rejuvenates mitochondria in the aged cardiomyocyte., PMID:33319746
Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition., PMID:33308446
For research use only. Not for human or drug use.
