Catalog No.
YHC44701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu210
Predicted molecular weight
25.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P09960
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Leukotriene A-4 hydrolase, LTA-4 hydrolase, 3.3.2.6, Leukotriene A(4) hydrolase, Tripeptide aminopeptidase LTA4H, 3.4.11.4, LTA4H, LTA4
Down-regulating HDAC2-LTA4H pathway ameliorates renal ischemia-reperfusion injury., PMID:40324735
Morus alba L.-Glycyrrhiza uralensis alleviate chronic obstructive pulmonary disease by inhibiting the arachidonic acid metabolism pathway., PMID:40324701
Microscale Proteomic Analysis of the Endolymphatic Sac in Menière's Disease Patients., PMID:40062362
LTA4H improves the tumor microenvironment and prevents HCC progression via targeting the HNRNPA1/LTBP1/TGF-β axis., PMID:40056904
Identification of mitophagy-related key genes and their correlation with immune cell infiltration in acute myocardial infarction via bioinformatics analysis., PMID:39872885
Alpha-Lipoic Acid-Mediated Inhibition of LTB4 Synthesis Suppresses Epithelial-Mesenchymal Transition, Modulating Functional and Tumorigenic Capacities in Non-Small Cell Lung Cancer A549 Cells., PMID:39816494
The analgesic effects of Yu-Xue-Bi tablet (YXB) on mice with inflammatory pain by regulating LXA4-FPR2-TRPA1 pathway., PMID:39107849
[Mechanism of Puerariae Thomsonii Radix in treatment of mild dyslipidemia: based on clinical metabolomics and proteomics]., PMID:38812181
The plasma proteome differentiates the multisystem inflammatory syndrome in children (MIS-C) from children with SARS-CoV-2 negative sepsis., PMID:38632526
Human genetic associations of the airway microbiome in chronic obstructive pulmonary disease., PMID:38622589
Targeting LTA4H facilitates the reshaping of the immune microenvironment mediated by CCL5 and sensitizes ovarian cancer to Cisplatin., PMID:38300441
Activation of leukotriene B4 receptor 1 is a prerequisite for complement receptor 3-mediated antifungal responses of neutrophils., PMID:38297112
An immune-related exosome signature predicts the prognosis and immunotherapy response in ovarian cancer., PMID:38238671
Exploring Potential Biomarkers of Early Thymoma based on Serum Proteomics., PMID:38053354
HLA-C*15:02 and epidermal growth factor receptor inhibitor-induced erosive pustular dermatosis of the scalp., PMID:37710038
Serum proteomics identifies S100A11 and MMP9 as novel biomarkers for predicting the early efficacy of sublingual immunotherapy in allergic rhinitis., PMID:37647677
Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice., PMID:37589142
Genome-Wide Association Study Identifies 4 Novel Risk Loci for Small Intestinal Neuroendocrine Tumors Including a Missense Mutation in LGR5., PMID:37453564
Lipoxin receptor agonist and inhibition of LTA4 hydrolase prevent tight junction disruption caused by P. aeruginosa filtrate in airway epithelial cells., PMID:37406028
Repurposing of neprilysin inhibitor 'sacubitrilat' as an anti-cancer drug by modulating epigenetic and apoptotic regulators., PMID:37336927
Integrative proteomic profiling of lung tissues and blood in acute respiratory distress syndrome., PMID:37197655
Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A4 Hydrolase., PMID:37108702
Inhibition of Leukotriene A4 Hydrolase Suppressed Cartilage Degradation and Synovial Inflammation in a Mouse Model of Experimental Osteoarthritis., PMID:37086004
Endothelial Protein kinase D1 is a major regulator of post-traumatic hyperinflammation., PMID:36936923
LTA4H extensively associates with mRNAs and lncRNAs indicative of its novel regulatory targets., PMID:36923505
Comparative Genetic Association Analysis of Human Genetic Susceptibility to Pulmonary and Lymph Node Tuberculosis., PMID:36672948
Leukotriene A4 Hydrolase and Hepatocyte Growth Factor Are Risk Factors of Sudden Cardiac Death Due to First-Ever Myocardial Infarction., PMID:36142157
Compilation and evaluation of a fatty acid mimetics screening library., PMID:35907497
Prospective Proteomic Study Identifies Potential Circulating Protein Biomarkers for Colorectal Cancer Risk., PMID:35805033
The IRE1α Inhibitor KIRA6 Blocks Leukotriene Biosynthesis in Human Phagocytes., PMID:35392553
An inhibitor of leukotriene-A4 hydrolase from bat salivary glands facilitates virus infection., PMID:35238649
LTB4 Promotes Acute Lung Injury via Upregulating the PLCε-1/TLR4/NF-κB Pathway in One-Lung Ventilation., PMID:35059042
Molecular and Immunohistochemical Expression of LTA4H and FXR1 in Canine Oral Melanoma., PMID:34966807
Extract, fractions, and ethyl-p-methoxycinnamate isolate from Kaempferia galanga Elicit anti-inflammatory activity by limiting leukotriene B4 (LTB4) production., PMID:34765520
Immune reconstitution inflammatory syndrome in non-HIV cryptococcal meningitis: Cross-talk between pathogen and host., PMID:34390048
Affinity ultrafiltration and UPLC-HR-Orbitrap-MS based screening of thrombin-targeted small molecules with anticoagulation activity from Poecilobdella manillensis., PMID:34147951
Bestatin Cream Impairs Solar Simulated Light‒Driven Skin Inflammation and Skin Carcinogenesis in Mice., PMID:34051272
Astragaloside IV Alleviates Liver Inflammation, Oxidative Stress and Apoptosis to Protect Against Experimental Non-Alcoholic Fatty Liver Disease., PMID:33953586
Baicalin and Geniposide Inhibit Polarization and Inflammatory Injury of OGD/R-Treated Microglia by Suppressing the 5-LOX/LTB4 Pathway., PMID:33891262
Development and in vitro Profiling of Dual FXR/LTA4H Modulators., PMID:33856122
Aminopeptidase Expression in Multiple Myeloma Associates with Disease Progression and Sensitivity to Melflufen., PMID:33810334
Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone., PMID:33658385
A Bayesian analysis of the association between Leukotriene A4 Hydrolase genotype and survival in tuberculous meningitis., PMID:33416499
Neurotuberculosis: an update., PMID:33400226
Leukotriene A4 Hydrolase Is a Candidate Predictive Biomarker for Successful Allergen Immunotherapy., PMID:33329520
The impact of blood-processing time on the proteome of human peripheral blood mononuclear cells., PMID:33301959
Mechanism of Paeoniflorin in the Treatment of Bile Duct Ligation-Induced Cholestatic Liver Injury Using Integrated Metabolomics and Network Pharmacology., PMID:33192530
Dissecting the mechanism of Yuzhi Zhixue granule on ovulatory dysfunctional uterine bleeding by network pharmacology and molecular docking., PMID:33110441
Expression of leukotriene B4 receptor 1 defines functionally distinct DCs that control allergic skin inflammation., PMID:33037399
S1PR4 ablation reduces tumor growth and improves chemotherapy via CD8+ T cell expansion., PMID:32663191
For research use only. Not for human or drug use.
