Catalog No.
YHC30801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His217-Thr401
Predicted molecular weight
35.88 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08173
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Muscarinic acetylcholine receptor M4, CHRM4
CHRM4/AKT/MYCN upregulates interferon alpha-17 in the tumor microenvironment to promote neuroendocrine differentiation of prostate cancer., PMID:37142586
Muscarinic Receptors Expression in the Peripheral Blood Cells Differentiate Dementia with Lewy Bodies from Alzheimer's Disease., PMID:34806612
Nerve growth factor interacts with CHRM4 and promotes neuroendocrine differentiation of prostate cancer and castration resistance., PMID:33398073
Contributions of cholinergic receptor muscarinic 1 and CYP1A2 gene variants on the effects of plasma ratio of clozapine/N-desmethylclozapine on working memory in schizophrenia., PMID:33143542
Evaluation of Operational Models of Agonism and Allosterism at Receptors with Multiple Orthosteric Binding Sites., PMID:31704718
Evolution of the Muscarinic Acetylcholine Receptors in Vertebrates., PMID:30564629
In Vivo Modulation of Hippocampal Excitability by M4 Muscarinic Acetylcholine Receptor Activator: Implications for Treatment of Alzheimer's Disease and Schizophrenic Patients., PMID:30335349
Total RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M4 Muscarinic Receptor as a Novel Therapeutic Target., PMID:29523700
Sympathetic and parasympathetic innervation in hepatocellular carcinoma., PMID:28895408
Cholinergic and perfusion brain networks in Parkinson disease dementia., PMID:27306636
African-specific variability in the acetylcholine muscarinic receptor M4: association with cocaine and heroin addiction., PMID:27269905
Ocular biomarkers of Alzheimer's disease., PMID:25788142
An investigation of the factors that regulate muscarinic receptor expression in schizophrenia., PMID:25037527
For research use only. Not for human or drug use.
