Catalog No.
YHC23501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser181-Gly392
Predicted molecular weight
24.67 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P07199
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Major centromere autoantigen B, Centromere protein B, CENP-B, CENPB
Conservation of dichromatin organization along regional centromeres., PMID:40147439
A fission yeast CENP-B homolog Abp1 prevents RNAi-mediated heterochromatin formation at ribosomal DNA repeats., PMID:40132111
Independence of centromeric and pericentromeric chromatin stability on CCAN components., PMID:39937678
CENP-A/CENP-B uncoupling in the evolutionary reshuffling of centromeres in equids., PMID:39915813
Should We Adopt Increased Dilutions for Indirect Immunofluorescence in Pediatric Anti-Centromere Antibody Testing? Insights from a Three-Year Retrospective Study., PMID:39857867
Independence of Centromeric and Pericentromeric Chromatin Stability on CCAN Components., PMID:39763731
Novel role of zinc-finger protein 518 in heterochromatin formation on α-satellite DNA., PMID:39673523
FBXO38 is dispensable for PD-1 regulation., PMID:39266770
A Case of Scleroderma With Coexisting Multiple Myeloma and Bullous Pemphigoid., PMID:39252723
Autoimmune diseases, autoantibody status and silicosis in a cohort of 1238 workers from the artificial stone benchtop industry., PMID:39134395
Molecular evolution of the mammalian kinetochore complex., PMID:38979348
JRK binds satellite III DNA and is necessary for the heat shock response., PMID:38946594
Coexistence of systemic sclerosis and cryopyrin-associated periodic syndrome., PMID:38940218
Vertebrate centromere architecture: from chromatin threads to functional structures., PMID:38856923
Neuronal autoantibodies in the cerebrospinal fluid of 148 patients with schizophrenia and 151 healthy controls., PMID:38770306
Analysis of CENP-B Boxes as Anchor of Kinetochores in Centromeres of Human Chromosomes., PMID:38690324
Detection of IgE-autoantibodies to nuclear antigens in patients with systemic sclerosis and analysis of their clinical relevance., PMID:38530662
TRANSCRIPTOME ANALYSIS REVEALED THE MOLECULAR SIGNATURES OF CISPLATIN-FLUOROURACIL COMBINED CHEMOTHERAPY RESISTANCE IN GASTRIC CANCER., PMID:38325291
[Clinical and immunological features of primary Sjögren's syndrome patients with positive anti-centromere protein B antibody]., PMID:38101794
CENP-A and CENP-B collaborate to create an open centromeric chromatin state., PMID:38086807
Centromere innovations within a mouse species., PMID:37967185
CENPB promotes the proliferation of hepatocellular carcinoma and is directly regulated by miR-29a., PMID:37925172
Clinical value of chemiluminescence method for detection of antinuclear antibody profiles., PMID:37901001
Diversity and Evolution of Highly Repetitive DNA Sequences Constituting Chromosome Site-Specific Heterochromatin in Two Gerbillinae Species., PMID:37708873
Autoantibodies associated with systemic sclerosis in three autoimmune diseases imprinted by type I interferon gene dysregulation: a comparison across SLE, primary Sjögren's syndrome and systemic sclerosis., PMID:36581379
Molecular Cytogenetic Characterization of C-Band-Positive Heterochromatin of the Greater Long-Tailed Hamster (Tscherskia triton, Cricetinae)., PMID:36535261
Feasibility of Indirect immunofluorescence (IIF) alone as a screening method for antinuclear antibody in connective diseases in India's sub-Himalayan region., PMID:36308197
Polystyrene nanoparticles enhance the adverse effects of di-(2-ethylhexyl) phthalate on male reproductive system in mice., PMID:36174316
Cytotoxic effect of combining two antisense oligonucleotides against telomerase rna component (hTR and mRNA of centromere protein B (CENP-B) in hepatocellular carcinoma cells., PMID:35894385
Seropositive Neuromyelitis Optica in a Case of Undiagnosed Ankylosing Spondylitis: A Neuro-Rheumatological Conundrum., PMID:35864917
FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability., PMID:35813202
Analytical and clinical performance of different platforms simultaneously detecting 15 antinuclear antibodies., PMID:35708068
Current technologies for anti-ENA antibody detection: State-of-the-art of diagnostic immunoassays., PMID:35690095
Serum Biomarker Panel for Rapid Early Diagnosis of Lung Cancer., PMID:35616661
Combination of CENP-B Box Positive and Negative Synthetic Alpha Satellite Repeats Improves De Novo Human Artificial Chromosome Formation., PMID:35563684
CENP-B-mediated DNA loops regulate activity and stability of human centromeres., PMID:35320753
Gastroparesis in systemic sclerosis: a detailed analysis using whole-gut scintigraphy., PMID:35136977
[Investigation of the Contribution of Autoantibodies to Clinical Diagnosis in Liver Pathologies and the Identification of Accompanying Autoimmune Diseases]., PMID:35088962
Systemic Sclerosis in Zimbabwe: Autoantibody Biomarkers, Clinical, and Laboratory Correlates., PMID:34858387
CENP-B promotes the centromeric localization of ZFAT to control transcription of noncoding RNA., PMID:34547289
LINC01123 potentially correlates with radioresistance in glioma through the miR-151a/CENPB axis., PMID:34519373
Alpha Satellite Insertion Close to an Ancestral Centromeric Region., PMID:34464971
Parallel pathways for recruiting effector proteins determine centromere drive and suppression., PMID:34433012
Anticentromere antibody induced by immunization with centromere protein and Freund's complete adjuvant may interfere with mouse early-stage embryo., PMID:34416895
Comparison of antinuclear antibody profiles obtained using line immunoassay and fluorescence enzyme immunoassay., PMID:34154430
Combining multi-antigenic immunodot with indirect immunofluorescence on HEp-2 cells improves the diagnosis of systemic sclerosis., PMID:34111525
Centromeric transcription maintains centromeric cohesion in human cells., PMID:33881484
High expression levels of centromere protein A plus upregulation of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling pathway affect chemotherapy response and prognosis in patients with breast cancer., PMID:33841571
Massive parallel sequencing in a family with rectal cancer., PMID:33827643
Autoantibody profiles in systemic sclerosis; a comparison of diagnostic tests., PMID:33818234
For research use only. Not for human or drug use.
