Catalog No.
YHC03401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
[Trp30-Lys58] & [Pro116-Ser148] & [Ser299-Thr323]
Predicted molecular weight
25.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P03891
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NADH-ubiquinone oxidoreductase chain 2, 7.1.1.2, NADH dehydrogenase subunit 2, MT-ND2, MTND2, NADH2, ND2
Exploring the Mechanism of Kai-Xin-San to Improve Cognitive Deficits in AD Rats Induced by D-Gal and Aβ25-35 Based on Multi-Omics and Network Analysis., PMID:40033867
Changes in the Phenotype and Metabolism of Peritoneal Macrophages in Mucin-2 Knockout Mice and Partial Restoration of Their Functions In Vitro After L-Fucose Treatment., PMID:39795876
Spontaneous mutation in 2310061I04Rik results in reduced expression of mitochondrial genes and impaired brain myelination., PMID:39631040
Identification of new therapeutic targets related to endoplasmic reticulum stress and mitochondrial dysfunction to reduce the risk of rupture in degenerative ascending aortic aneurysm., PMID:39424523
Ribosome Profiling and Mass Spectrometry Reveal Widespread Mitochondrial Translation Defects in a Striatal Cell Model of Huntington Disease., PMID:38447791
The mutational analysis of mitochondrial DNA in maternal inheritance of polycystic ovarian syndrome., PMID:37674615
Mitochondria-wide association study observed significant interactions of mitochondrial respiratory and the inflammatory in the development of anxiety and depression., PMID:37344456
"Mitochondrial pathogenic mutations and metabolic alterations associated with COVID-19 disease severity"., PMID:36832542
Mutations in Complex I of the Mitochondrial Electron-Transport Chain Sensitize the Fruit Fly (Drosophila melanogaster) to Ether and Non-Ether Volatile Anesthetics., PMID:36768163
Mitochondrial mutations in protein coding genes of respiratory chain including complexes IV, V, and mt-tRNA genes are associated risk factors for congenital heart disease., PMID:36483916
Single-Cell RNA-Seq Analysis of Cells from Degenerating and Non-Degenerating Intervertebral Discs from the Same Individual Reveals New Biomarkers for Intervertebral Disc Degeneration., PMID:35409356
Next-generation sequencing of the whole mitochondrial genome identifies functionally deleterious mutations in patients with multiple sclerosis., PMID:35130313
Protective Effect of Mitochondrial ND2 C5178A Gene Mutation on Cell and Mitochondrial Functions., PMID:34336093
Mechanism of Naringenin Blocking the Protection of LTB4/BLT1 Receptor Against Septic Cardiac Dysfunction., PMID:33334792
Integrative taxonomy identifies a new stingray species of the genus Hypanus Rafinesque, 1818 (Dasyatidae, Myliobatiformes), from the Tropical Southwestern Atlantic., PMID:32743805
Analysis of variants in mitochondrial genome and their putative pathogenicity in tuberculosis patients from Mizoram, North east India., PMID:32652230
Pediatric leukemia could be driven predominantly by non-synonymous variants in mitochondrial complex V in Mizo population from Northeast India., PMID:32609037
H2 O2 -induced oxidative stress disrupts mitochondrial functions and impairs migratory potential of human epidermal melanocytes., PMID:32580253
Association between mitochondrial genetic variation and breast cancer risk: The Multiethnic Cohort., PMID:31577800
Mitochondrial DNA sequencing reveals association of variants and haplogroup M33a2'3 with High altitude pulmonary edema susceptibility in Indian male lowlanders., PMID:31358833
Maternally Inherited Differences within Mitochondrial Complex I Control Murine Healthspan., PMID:31337008
Disease-causing mutations in subunits of OXPHOS complex I affect certain physical interactions., PMID:31292494
miR-450a Acts as a Tumor Suppressor in Ovarian Cancer by Regulating Energy Metabolism., PMID:31101765
Whole mitochondria genome mutational spectrum in occupationally exposed lead subjects., PMID:31029642
Pharmacological inhibition of TLR4/NF-κB with TLR4-IN-C34 attenuated microcystin-leucine arginine toxicity in bovine Sertoli cells., PMID:30671980
Sodium Selenite inhibits mitophagy, downregulation and mislocalization of blood-testis barrier proteins of bovine Sertoli cell exposed to microcystin-leucine arginine (MC-LR) via TLR4/NF-kB and mitochondrial signaling pathways blockage., PMID:30267989
Mitochondrial DNA Variation and Disease Susceptibility in Primary Open-Angle Glaucoma., PMID:30242360
Association between sperm mitochondrial ND2 gene variants and total fertilization failure., PMID:29577757
Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1., PMID:28813576
Novel non-neutral mitochondrial DNA mutations found in childhood acute lymphoblastic leukemia., PMID:28708239
Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth., PMID:28500171
Genetic diversities of MT-ND1 and MT-ND2 genes are associated with high-altitude adaptation in yak., PMID:28366030
Mitochondrial Gene Expression Profiles Are Associated with Maternal Psychosocial Stress in Pregnancy and Infant Temperament., PMID:26418562
Synergistic neuroprotection by epicatechin and quercetin: Activation of convergent mitochondrial signaling pathways., PMID:26363153
Association of Genes, Pathways, and Haplogroups of the Mitochondrial Genome with the Risk of Colorectal Cancer: The Multiethnic Cohort., PMID:26340450
The expression characteristics of mt-ND2 gene in chicken., PMID:26332376
Whole mitochondrial genome analysis in two families with dilated mitochondrial cardiomyopathy: detection of mutations in MT-ND2 and MT-TL1 genes., PMID:26258512
Association of the mt-ND2 5178A/C polymorphism with Parkinson's disease., PMID:25511548
RNF14 is a regulator of mitochondrial and immune function in muscle., PMID:24472305
Mitochondrial NADH dehydrogenase polymorphisms are associated with breast cancer in Poland., PMID:24414975
Hypothalamic and amygdalar cell lines differ markedly in mitochondrial rather than nuclear encoded gene expression., PMID:23800343
Association of a missense nucleotide polymorphism in the MT-ND2 gene with mitochondrial reactive oxygen species production in the Tibet chicken embryo incubated in normoxia or simulated hypoxia., PMID:23347088
Mitochondrial mutations are associated with atherosclerotic lesions in the human aorta., PMID:22997526
PGC-1β mediates adaptive chemoresistance associated with mitochondrial DNA mutations., PMID:22777349
Nonsynonymous variants in mt-Nd2, mt-Nd4, and mt-Nd5 are linked to effects on oxidative phosphorylation and insulin sensitivity in rat conplastic strains., PMID:22414913
Role of genetics in resistance to type 1 diabetes., PMID:22069272
mt-Nd2(a) Modifies resistance against autoimmune type 1 diabetes in NOD mice at the level of the pancreatic β-cell., PMID:20980458
New insights into the evolution of intronic sequences of the beta-fibrinogen gene and their application in reconstructing mustelid phylogeny., PMID:18624576
Altered expression of 12S/MT-RNR1, MT-CO2/COX2, and MT-ATP6 mitochondrial genes in prostate cancer., PMID:18409190
mt-Nd2a suppresses reactive oxygen species production by mitochondrial complexes I and III., PMID:18281288
For research use only. Not for human or drug use.
