Catalog No.
YHB46901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val1091-Met1247
Predicted molecular weight
19.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O94885
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
SAM and SH3 domain-containing protein 1, Proline-glutamate repeat-containing protein, SASH1, KIAA0790, PEPE1
SASH1 Mutations and Hereditary Disorders of Pigmentation: Review of Literature., PMID:40511878
Case report: Clinicopathological characteristics of SASH1 mutation-related dyschromatosis: a rethinking of the classification of dyschromatosis., PMID:40115815
Multi-omics integration reveals immune hallmarks and biomarkers associated with FLT3 inhibitor sensitivity in FLT3-mutated AML., PMID:40115132
Sam-Sam Association Between EphA2 and SASH1: In Silico Studies of Cancer-Linked Mutations., PMID:39942820
SASH1 is a novel binding partner to disassemble Caskin1 tandem SAM homopolymer through heterogeneous SAM-SAM interaction., PMID:39688081
The downregulation of SASH1 expression promotes breast cancer occurrence and invasion accompanied by the activation of PI3K-Akt-mTOR signaling pathway., PMID:39300116
Exploring serine-arginine rich splicing factors: potential predictive markers for dysregulation in oral cancer., PMID:39227899
Effect of Mifepristone on Migration and Proliferation of Oral Cancer Cells., PMID:39201464
SASH1 S519N Variant Links Skin Hyperpigmentation and Premature Hair Graying to Dysfunction of Melanocyte Lineage., PMID:38848986
Blockade of a novel MAP4K4-LATS2-SASH1-YAP1 cascade inhibits tumorigenesis and metastasis in luminal breast cancer., PMID:38657867
Hepatitis B virus evades the immune system by suppressing the NF-κB signaling pathway with DENND2A., PMID:38240571
TBM Hunter: Identify and Score Canonical, Extended, and Unconventional Tankyrase-Binding Motifs in Any Protein., PMID:38069287
Identification of Key Osteoporosis Genes Through Comparative Analysis of Men's and Women's Osteoblast Transcriptomes., PMID:37878026
Novel Alzheimer's disease genes and epistasis identified using machine learning GWAS platform., PMID:37848535
SASH1 interacts with TNKS2 and promotes human melanocyte stem cell maintenance., PMID:37808724
HMGB1/SET/HAT1 complex-mediated SASH1 repression drives glycolysis and metastasis in lung adenocarcinoma., PMID:37794134
SASH1 contributes to glial cell migration in the early development of the central nervous system., PMID:37741309
SASH1: A Novel Eph Receptor Partner and Insights into SAM-SAM Interactions., PMID:37619706
Uncovering a new SASH1 mutation associated with dyschromatosis universalis hereditaria using whole-exome-sequencing: A case report., PMID:37543808
Human Endogenous Retrovirus-H-Derived miR-4454 Inhibits the Expression of DNAJB4 and SASH1 in Non-Muscle-Invasive Bladder Cancer., PMID:37510314
Two novel mutations in SASH1 identified in a familial and a sporadic generalized lentiginosis phenotype in Koreans., PMID:37337450
Identification and validation of differentially expressed genes for targeted therapy in NSCLC using integrated bioinformatics analysis., PMID:37324026
Drug resistance related genes in lung adenocarcinoma predict patient prognosis and influence the tumor microenvironment., PMID:37322027
The Structural Dynamics, Complexity of Interactions, and Functions in Cancer of Multi-SAM Containing Proteins., PMID:37296980
Solution NMR backbone assignment of the SASH1 SLy proteins associated disordered region (SPIDER)., PMID:37155029
Single-cell RNA sequencing reveals the transcriptomic landscape of kidneys in patients with ischemic acute kidney injury., PMID:37083129
A SAMD5-SASH1 fusion in solitary infantile myofibromatosis., PMID:36861442
The PER3rs772027021 SNP induces pigmentation phenotypes of dyschromatosis universalis hereditaria., PMID:36790533
Identification of Smoking-Associated Transcriptome Aberration in Blood with Machine Learning Methods., PMID:36644165
Hypoxia-Inducible Factor-2-Altered Urothelial Carcinoma: Clinical and Genomic Features., PMID:36421334
SAM1 domain of SASH1 harbors distinctive structural heterogeneity., PMID:36341956
Depletion of SASH1, an astrocyte differentiation-related gene, contributes to functional recovery in spinal cord injury., PMID:36286186
SASH1 knockdown suppresses TRAF6 ubiquitination to regulate hemangioma progression by mediating EZH2 degradation., PMID:35772492
Expression of lncRNA MIR193BHG in serum of preeclampsia patients and its clinical significance., PMID:35301154
LncRNA IFITM4P promotes immune escape by up-regulating PD-L1 via dual mechanism in oral carcinogenesis., PMID:35051616
[Genetics of complex and syndromic palmoplantar keratoderma]., PMID:34961738
miR-1307 promotes hepatocarcinogenesis by CALR-OSTC-endoplasmic reticulum protein folding pathway., PMID:34761190
Novel missense mutation of SASH1 in a Chinese family with dyschromatosis universalis hereditaria., PMID:34174894
Two novel SASH1 mutations in Chinese families with dyschromatosis universalis hereditaria., PMID:34028087
The emerging and diverse roles of the SLy/SASH1-protein family in health and disease-Overview of three multifunctional proteins., PMID:33710696
Use tumor suppressor genes as biomarkers for diagnosis of non-small cell lung cancer., PMID:33580150
CircRNA Circ-ITCH Inhibits the Proliferation and Invasion of Glioma Cells Through Targeting the miR-106a-5p/SASH1 Axis., PMID:33571015
The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing., PMID:33569544
AAV1-Mediated shRNA Knockdown of SASH1 in Rat Bronchus Attenuates Hypoxia-Induced Pulmonary Artery Remodeling., PMID:33297837
Genomic profile of MYCN non-amplified neuroblastoma and potential for immunotherapeutic strategies in neuroblastoma., PMID:33172452
Expression of SASH1 in Preeclampsia and Its Effects on Human Trophoblast., PMID:33134379
SASH1 is a prognostic indicator and potential therapeutic target in non-small cell lung cancer., PMID:33122723
Five novel mutations in SASH1 contribute to lentiginous phenotypes in Japanese families., PMID:32981204
Paired like homeodomain 1 and SAM and SH3 domain-containing 1 in the progression and prognosis of head and neck squamous cell carcinoma., PMID:32905855
Silencing SCAMP1-TV2 Inhibited the Malignant Biological Behaviors of Breast Cancer Cells by Interaction With PUM2 to Facilitate INSM1 mRNA Degradation., PMID:32670859
For research use only. Not for human or drug use.
