Catalog No.
YHB26801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln191-Pro318
Predicted molecular weight
17.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75618
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Death effector domain-containing protein, DEDPro1, Death effector domain-containing testicular molecule, FLDED-1, DEDD, DEDPRO1, DEFT, KE05
Conserved domains and structural motifs that differentiate closely related Rex1 and Rex3 DEDDh exoribonucleases are required for their function in yeast., PMID:40455837
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD., PMID:40032841
Calcium electroporation induces stress response through upregulation of HSP27, HSP70, aspartate β-hydroxylase, and CD133 in human colon cancer cells., PMID:39980072
Distinct roles of small extracellular vesicles from resident and infiltrating macrophages on glioma growth and mobility., PMID:39781357
Structural and bioinformatics analyses identify deoxydinucleotide-specific nucleases and their association with genomic islands in gram-positive bacteria., PMID:39778863
The Legionella pneumophila effector PieF modulates mRNA stability through association with eukaryotic CCR4-NOT., PMID:39699231
TOE1 deadenylase inhibits gastric cancer cell proliferation by regulating cell cycle progression., PMID:39657841
Structural and mechanistic insights into a mesophilic prokaryotic Argonaute., PMID:39315697
Genetic requirements for uropathogenic E. coli proliferation in the bladder cell infection cycle., PMID:39287381
In Vivo Cross-Linking Sheds Light on the Salmonella Divisome in Which PBP3 and PBP3SAL Compete for Occupancy., PMID:39233506
POLD1 DEDD Motif Mutation Confers Hypermutation in Endometrial Cancer and Durable Response to Pembrolizumab., PMID:38067377
CpCAF1 from Chimonanthus praecox Promotes Flowering and Low-Temperature Tolerance When Expressed in Arabidopsis thaliana., PMID:37629126
Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication., PMID:37515225
Genomic and transcriptomic analyses enable the identification of important genes associated with subcutaneous fat deposition in Holstein cows., PMID:36738887
ISG20: an enigmatic antiviral RNase targeting multiple viruses., PMID:35174977
Contribution of domain structure to the function of the yeast DEDD family exoribonuclease and RNase T functional homolog, Rex1., PMID:35082142
Transcriptomics Analysis Identifies the Presence of Upregulated Ribosomal Housekeeping Genes in the Alveolar Macrophages of Patients with Smoking-Induced Chronic Obstructive Pulmonary Disease., PMID:34588774
Structural characterization of NrnC identifies unifying features of dinucleotidases., PMID:34533457
Autophagy induction regulates aquaporin 3-mediated skin fibroblast ageing., PMID:34319590
New targets for drug design: importance of nsp14/nsp10 complex formation for the 3'-5' exoribonucleolytic activity on SARS-CoV-2., PMID:33705595
SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli., PMID:33144379
DrpB (YedR) Is a Nonessential Cell Division Protein in Escherichia coli., PMID:32900831
Competition between maturation and degradation drives human snRNA 3' end quality control., PMID:32499401
CaV3.1 channel pore pseudo-symmetry revealed by selectivity filter mutations in its domains I/II., PMID:32428730
Low DEDD expression in breast cancer cells indicates higher sensitivity to the Bcl-2-specific inhibitor ABT-199., PMID:32113682
Death effector domain-containing protein induces vulnerability to cell cycle inhibition in triple-negative breast cancer., PMID:31253784
The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases., PMID:31110294
MCL1 and DEDD Promote Urothelial Carcinoma Progression., PMID:30777879
Roles of the DedD Protein in Escherichia coli Cell Constriction., PMID:30692172
TOE1 acts as a 3' exonuclease for telomerase RNA and regulates telomere maintenance., PMID:30371886
Comprehensive analysis of coexpressed long noncoding RNAs and genes in breast cancer., PMID:30362198
Long Noncoding RNA LINC00472 Inhibits Proliferation and Promotes Apoptosis of Lung Adenocarcinoma Cells via Regulating miR-24-3p/ DEDD., PMID:30175664
Stress-induced nuclear depletion of Entamoeba histolytica 3'-5' exoribonuclease EhRrp6 and its role in growth and erythrophagocytosis., PMID:30171071
MicroRNA-17 inhibition overcomes chemoresistance and suppresses epithelial-mesenchymal transition through a DEDD-dependent mechanism in gastric cancer., PMID:29953965
YtfB, an OapA Domain-Containing Protein, Is a New Cell Division Protein in Escherichia coli., PMID:29686141
Characterization of Echinostoma cinetorchis endoribonuclease, RNase H., PMID:28877580
The Inhibitory Effect of Ginger Extract on Ovarian Cancer Cell Line; Application of Systems Biology., PMID:28761826
Alternative splicing of CNOT7 diversifies CCR4-NOT functions., PMID:28591869
Analysis of Argonaute Complex Bound mRNAs in DU145 Prostate Carcinoma Cells Reveals New miRNA Target Genes., PMID:28163933
miR-24-3p regulates bladder cancer cell proliferation, migration, invasion and autophagy by targeting DEDD., PMID:28000900
A requirement for cell elongation protein RodZ and cell division proteins FtsN and DedD to maintain the small rod morphology of Escherichia coli at growth temperatures near 8°C., PMID:27477251
Cd(2+) sensitivity and permeability of a low voltage-activated Ca(2+) channel with CatSper-like selectivity filter., PMID:27134080
Identification and Testing of Novel CARP-1 Functional Mimetic Compounds as Inhibitors of Non-Small Cell Lung and Triple Negative Breast Cancers., PMID:26485930
Bacterial SPOR domains are recruited to septal peptidoglycan by binding to glycan strands that lack stem peptides., PMID:26305949
Metazoan Maelstrom is an RNA-binding protein that has evolved from an ancient nuclease active in protists., PMID:25778731
Tandem DEDs and CARDs suggest novel mechanisms of signaling complex assembly., PMID:25398537
Use of the tumor repressor DEDD as a prognostic marker of cancer metastasis., PMID:24839027
Divergence of the expression and subcellular localization of CCR4-associated factor 1 (CAF1) deadenylase proteins in Oryza sativa., PMID:24805883
Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo., PMID:24704253
Substantial conformational change mediated by charge-triad residues of the death effector domain in protein-protein interactions., PMID:24391764
For research use only. Not for human or drug use.
