Catalog No.
YHA84901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met53-Asp115
Predicted molecular weight
35.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60248
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein SOX-15, Protein SOX-12, Protein SOX-20, SOX15, SOX12, SOX20, SOX26, SOX27
CircVPS8 promotes the malignant phenotype and inhibits ferroptosis of glioma stem cells by acting as a scaffold for MKRN1, SOX15 and HNF4A., PMID:39098847
Engineering mouse cell fate controller by rational design., PMID:39043686
Statistical learning quantifies transposable element-mediated cis-regulation., PMID:37950299
[The Mechanism of miR-1294 Targeting SOX15 to Regulate Wnt/β-catenin Signaling Pathway and Promote the Proliferation of Acute Lymphoblastic Leukemia Cells in Children]., PMID:37096504
Genetic background of idiopathic neurodevelopmental delay patients with significant brain deviation volume., PMID:36806579
Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5., PMID:36764520
Evolutionary Landscape of SOX Genes to Inform Genotype-to-Phenotype Relationships., PMID:36672963
Transcriptome analyses in infertile men reveal germ cell-specific expression and splicing patterns., PMID:36446526
A chromosome-level genome of Semiothisa cinerearia provides insights into its genome evolution and control., PMID:36271350
SOX15 transcriptionally increases the function of AOC1 to modulate ferroptosis and progression in prostate cancer., PMID:35922412
Barrett's Metaplasia Progression towards Esophageal Adenocarcinoma: An Attempt to Select a Panel of Molecular Sensors and to Reflect Clinical Alterations by Experimental Models., PMID:35328735
Epigenetic Silencing of SOX15 Is Controlled by miRNAs rather than Methylation in Papillary Thyroid Cancer., PMID:34603557
The chromatin accessibility landscape reveals distinct transcriptional regulation in the induction of human primordial germ cell-like cells from pluripotent stem cells., PMID:33930315
Dissecting the epigenomic dynamics of human fetal germ cell development at single-cell resolution., PMID:32884136
SOX15 exerts antitumor function in glioma by inhibiting cell proliferation and invasion via downregulation of Wnt/β-catenin signaling., PMID:32416168
Downregulation of microR-147b represses the proliferation and invasion of thyroid carcinoma cells by inhibiting Wnt/β-catenin signaling via targeting SOX15., PMID:31760045
Testing the role of SOX15 in human primordial germ cell fate., PMID:31583280
dTcf/Pangolin suppresses growth and tumor formation in Drosophila., PMID:31235567
PseudoFuN: Deriving functional potentials of pseudogenes from integrative relationships with genes and microRNAs across 32 cancers., PMID:31029062
Inhibition of SOX15 Sensitizes Esophageal Squamous Carcinoma Cells to Paclitaxel., PMID:30950353
SOX11 hypermethylation as a tumor biomarker in endometrial cancer., PMID:30935961
The miR-96 and RARγ signaling axis governs androgen signaling and prostate cancer progression., PMID:30120411
Effects of SOX15 on the colorectal cancer cells via downregulation of the Wnt/β-catenin signaling pathway., PMID:30019915
5-Aminolevulinic acid-mediated photodynamic therapy can target human glioma stem-like cells refractory to antineoplastic agents., PMID:29990642
SOX2 and SOX12 are predictive of prognosis in patients with clear cell renal cell carcinoma., PMID:29541226
Patterning the gastrointestinal epithelium to confer regional-specific functions., PMID:29339095
HMG-box factor SoxD/Sox15 and homeodomain-containing factor Xanf1/Hesx1 directly interact and regulate the expression of Xanf1/Hesx1 during early forebrain development in Xenopus laevis., PMID:28918251
SOX15 regulates proliferation and migration of endometrial cancer cells., PMID:28821564
The cross-regulation between SOX15 and Wnt signaling pathway., PMID:28092101
Enhanced expression of the stemness-related factors OCT4, SOX15 and TWIST1 in ectopic endometrium of endometriosis patients., PMID:27881125
Adipose-derived stem cells from lean and obese humans show depot specific differences in their stem cell markers, exosome contents and senescence: role of protein kinase C delta (PKCδ) in adipose stem cell niche., PMID:27358894
SOX15 governs transcription in human stratified epithelia and a subset of esophageal adenocarcinomas., PMID:26516633
Diverse Targets of β-Catenin during the Epithelial-Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse., PMID:26122848
The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells., PMID:26046443
SOX15 and other SOX family members are important mediators of tumorigenesis in multiple cancer types., PMID:25594027
Transcriptional targets of Foxd3 in murine ES cells., PMID:24270162
Single nucleotide polymorphisms associated with non-contact soft tissue injuries in elite professional soccer players: influence on degree of injury and recovery time., PMID:23890452
CDX2 regulates multiple trophoblast genes in bovine trophectoderm CT-1 cells., PMID:23836438
SOX15 is a candidate tumor suppressor in pancreatic cancer with a potential role in Wnt/β-catenin signaling., PMID:23318427
Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation., PMID:23300844
Characterisation and expression during sex differentiation of Sox19 from the sea bass Dicentrarchus labrax., PMID:22940139
Deciphering the Sox-Oct partner code by quantitative cooperativity measurements., PMID:22344693
Defining hypo-methylated regions of stem cell-specific promoters in human iPS cells derived from extra-embryonic amnions and lung fibroblasts., PMID:20885964
Constitutive expression of pluripotency-associated genes in mesodermal progenitor cells (MPCs)., PMID:20360837
Function and molecular evolution of mammalian Sox15, a singleton in the SoxG group of transcription factors., PMID:19909824
Expression pattern of stemness-related genes in human endometrial and endometriotic tissues., PMID:19690622
SOX15 and SOX7 differentially regulate the myogenic program in P19 cells., PMID:19489079
Derivation of a novel undifferentiated human foetal phenotype in serum-free cultures with BMP-2., PMID:19438813
Complex interplay of three transcription factors in controlling the tormogen differentiation program of Drosophila mechanoreceptors., PMID:19232522
Evolution of non-coding regulatory sequences involved in the developmental process: reflection of differential employment of paralogous genes as highlighted by Sox2 and group B1 Sox genes., PMID:19212098
For research use only. Not for human or drug use.
