Catalog No.
YHA74901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Thr328
Predicted molecular weight
39.19 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43684
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mitotic checkpoint protein BUB3, BUB3
Disrupted MOS signaling alters meiotic cell cycle regulation and the egg transcriptome., PMID:40424049
Interplay of kinetochores and catalysts drives rapid assembly of the mitotic checkpoint complex., PMID:40410156
Localization and function of APC15 during mouse oocyte meiotic progression., PMID:40153087
Molecular mechanism of Mad2 conformational conversion promoted by the Mad2-interaction motif of Cdc20., PMID:40143766
mir-188-5p emerges as an oncomir to promote chronic myeloid leukemia via upregulation of BUB3 and SUMO2., PMID:40019654
Correction for Deng et al., The Arabidopsis BUB1/MAD3 family protein BMF3 requires BUB3.3 to recruit CDC20 to kinetochores in spindle assembly checkpoint signaling., PMID:40014562
Aneuploidy of specific chromosomes is beneficial to cells lacking spindle checkpoint protein Bub3., PMID:39903784
FRET-FLIM for the Study of Protein-Protein Interactions Underpinning Mitosis Checkpoints., PMID:39614049
Production of SAC Proteins in a Baculovirus-Based Heterologous Gene Expression System., PMID:39614045
A kinetochore-associated kinesin-7 motor cooperates with BUB3.3 to regulate mitotic chromosome congression in Arabidopsis thaliana., PMID:39414927
Aneuploidy of Specific Chromosomes is Beneficial to Cells Lacking Spindle Checkpoint Protein Bub3., PMID:39282354
Propylparaben exposure impairs G2/M and metaphase-anaphase transition during mouse oocyte maturation., PMID:39083874
A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in a pancreatic cancer cell line., PMID:38987356
Genetic Variations Affect Chemotherapy Outcomes: A Role of the Spindle-assembly Checkpoint., PMID:38953826
Kinetoplastid kinetochore proteins KKT14-KKT15 are divergent Bub1/BubR1-Bub3 proteins., PMID:38862021
YY2/BUB3 Axis promotes SAC Hyperactivation and Inhibits Colorectal Cancer Progression via Regulating Chromosomal Instability., PMID:38682484
Phospho-KNL-1 recognition by a TPR domain targets the BUB-1-BUB-3 complex to C. elegans kinetochores., PMID:38578284
Kinesin KIFC3 is essential for microtubule stability and cytokinesis in oocyte meiosis., PMID:38553728
The Arabidopsis BUB1/MAD3 family protein BMF3 requires BUB3.3 to recruit CDC20 to kinetochores in spindle assembly checkpoint signaling., PMID:38466841
Phospho-KNL-1 recognition by a TPR domain targets the BUB-1-BUB-3 complex to C. elegans kinetochores., PMID:38370671
A coadapted KNL1 and spindle assembly checkpoint axis orchestrates precise mitosis in Arabidopsis., PMID:38170753
Data-Independent Acquisition Mass Spectrometry Analysis of FFPE Rectal Cancer Samples Offers In-Depth Proteomics Characterization of the Response to Neoadjuvant Chemoradiotherapy., PMID:37895091
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3., PMID:37535603
Mad2 is dispensable for accurate chromosome segregation but becomes essential when oocytes are subjected to environmental stress., PMID:37485540
A spliceosome-associated gene signature aids in predicting prognosis and tumor microenvironment of hepatocellular carcinoma., PMID:37301543
Analysis of Bub3 and Nup75 in the Drosophila male germline lineage., PMID:37286104
Bub1 and Bub3 regulate metabolic adaptation via macrolipophagy in Drosophila., PMID:37027296
The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex., PMID:36934097
Distinct Aurora B pools at the inner centromere and kinetochore have different contributions to meiotic and mitotic chromosome segregation., PMID:36920098
Comprehensive analysis of BUBs gene family in lung adenocarcinoma with immunological analysis., PMID:36787437
Distinct Aurora B pools at the inner centromere and kinetochore have different contributions to meiotic and mitotic chromosome segregation., PMID:36778459
Evaluation of differentially expressed genes during replication using gene expression landscape of monkeypox-infected MK2 cells: A bioinformatics and systems biology approach to understanding the genomic pattern of viral replication., PMID:36724696
Hub Genes in Non-Small Cell Lung Cancer Regulatory Networks., PMID:36551208
Kinetochore-catalyzed MCC formation: A structural perspective., PMID:36518060
BUBR1 as a Prognostic Biomarker in Canine Oral Squamous Cell Carcinoma., PMID:36428310
Arrest of Cell Cycle by Avian Reovirus p17 through Its Interaction with Bub3., PMID:36366482
Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly., PMID:36289199
Label-Free Direct Mass Spectrometry Analysis of the Bystander Effects Induced in Chondrocytes by Chondrosarcoma Cells Irradiated with X-rays and Carbon Ions., PMID:36224025
Evaluation of the Spindle Assembly Checkpoint Integrity in Mouse Oocytes., PMID:36190266
Screening of genes encoding proteins that interact with ISG15: Probing a cDNA library from a snakehead fish cell line using a yeast two-hybrid system., PMID:35921933
The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis., PMID:35915203
Kinesin KIF15 regulates tubulin acetylation and spindle assembly checkpoint in mouse oocyte meiosis., PMID:35835966
Exploration of the Common Gene Characteristics and Molecular Mechanism of Parkinson's Disease and Crohn's Disease from Transcriptome Data., PMID:35741659
A role for the mitotic proteins Bub3 and BuGZ in transcriptional regulation of catalase-3 expression., PMID:35666721
Anticancer mechanism of 7-α-hydroxyfrullanolide on microtubules and computational prediction of its target binding in triple-negative breast cancer cells., PMID:35651747
BUB3, beyond the Simple Role of Partner., PMID:35631670
BUBs Are New Biomarkers of Promoting Tumorigenesis and Affecting Prognosis in Breast Cancer., PMID:35493295
Role of ubiquitin-protein ligase UBR5 in the disassembly of mitotic checkpoint complexes., PMID:35217622
Bioinformatics Analysis Reveals the Related Role of miR-511-5p in the Progression of Breast Cancer., PMID:35186236
miR-664b-3p inhibits colon cell carcinoma via negatively regulating Budding uninhibited by benzimidazole 3., PMID:35156516
For research use only. Not for human or drug use.
