Catalog No.
YHA74501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val26-Pro170
Predicted molecular weight
19.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43679
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
LIM domain-binding protein 2, LDB-2, Carboxyl-terminal LIM domain-binding protein 1, CLIM-1, LIM domain-binding factor CLIM1, LDB2, CLIM1
Weighted single-step genome-wide association study identified genomic regions and candidate genes for growth and reproductive traits in Wenchang chicken., PMID:40203724
Identification of quantitative trait loci and candidate genes associated with growth curve parameters in chinese wenshang barred chickens., PMID:39778364
Elucidation of the genetic determination of body weight and size in Chinese local chicken breeds by large-scale genomic analyses., PMID:38509464
Genome, HLA and polygenic risk score analyses for prevalent and persistent cervical human papillomavirus (HPV) infections., PMID:38200081
PDLIM1 interacts with HK2 to promote gastric cancer progression through enhancing the Warburg effect via Wnt/β-catenin signaling., PMID:37930472
Serum methylation of GALNT9, UPF3A, WARS, and LDB2 as noninvasive biomarkers for the early detection of colorectal cancer and advanced adenomas., PMID:37794510
Direct Knockdown of PDZ and LIM Domain 1 Using an Adenoviral Delivery System Accelerates Osteogenesis and Fracture Healing in Mice., PMID:37212284
PDLIM1 inhibits cell migration and invasion in diabetic retinopathy via negatively regulating Wnt3a., PMID:37037887
Oridonin Induces Apoptosis in Esophageal Squamous Cell Carcinoma by Inhibiting Cytoskeletal Protein LASP1 and PDLIM1., PMID:36677861
LIM-domain binding protein 2 was down-regulated by miRNA-96-5p inhibited the proliferation, invasion and metastasis of lung cancer H1299 cells., PMID:36473369
Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 and Its Related Molecules as Potential Biomarkers in Small-Cell Lung Cancer., PMID:35845940
Genome-Wide Association Study of Body Weight Traits in Inner Mongolia Cashmere Goats., PMID:34926636
Meta-analyses identify DNA methylation associated with kidney function and damage., PMID:34887417
Genomewide Association Analyses of Lactation Persistency and Milk Production Traits in Holstein Cattle Based on Imputed Whole-Genome Sequence Data., PMID:34828436
Serum Anti-PDLIM1 Autoantibody as Diagnostic Marker in Ovarian Cancer., PMID:34489945
Suppression of human colon tumor by EERAC through regulating Notch/DLL4/Hes pathway inhibiting angiogenesis in vivo., PMID:34476005
[LIM-domain binding protein 2 regulated by m6A modification inhibits lung adenocarcinoma cell proliferation in vitro]., PMID:33849822
Cooperation of LIM domain-binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia., PMID:33656268
Polygenetic-Risk Scores for A Glaucoma Risk Interact with Blood Pressure, Glucose Control, and Carbohydrate Intake., PMID:33114701
Distribution of PDLIM1 at actin-rich structures generated by invasive and adherent bacterial pathogens., PMID:33022122
Molecular characterization and a duplicated 31-bp indel within the LDB2 gene and its associations with production performance in chickens., PMID:32781192
Identification of hub driving genes and regulators of lung adenocarcinoma based on the gene Co-expression network., PMID:32196072
MicroRNA-370-3p inhibits cell proliferation and induces chronic myelogenous leukaemia cell apoptosis by suppressing PDLIM1/Wnt/β-catenin signaling., PMID:31986893
Crystal structure of human LDB1 in complex with SSBP2., PMID:31892537
Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome., PMID:31570581
PDLIM1 Inhibits Tumor Metastasis Through Activating Hippo Signaling in Hepatocellular Carcinoma., PMID:31509262
Reduced atherosclerosis lesion size, inflammatory response in miR-150 knockout mice via macrophage effects., PMID:29463607
LDB2 regulates the expression of DLL4 through the formation of oligomeric complexes in endothelial cells., PMID:28946938
Genome-wide association study of cardiotoxicity in the NCCTG N9831 (Alliance) adjuvant trastuzumab trial., PMID:28763429
The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis., PMID:27697904
Autophagy protects cardiomyocytes from the myocardial ischaemia-reperfusion injury through the clearance of CLP36., PMID:27512143
Autophagy regulates spermatid differentiation via degradation of PDLIM1., PMID:27310465
Cofactors of LIM Domains Associate with Estrogen Receptor α to Regulate the Expression of Noncoding RNA H19 and Corneal Epithelial Progenitor Cell Function., PMID:27129775
Autoantibodies against TYMS and PDLIM1 proteins detected as circulatory signatures in Indian breast cancer patients., PMID:27068564
Compensatory Actions of Ldb Adaptor Proteins During Corticospinal Motor Neuron Differentiation., PMID:26830346
PDLIM1 Stabilizes the E-Cadherin/β-Catenin Complex to Prevent Epithelial-Mesenchymal Transition and Metastatic Potential of Colorectal Cancer Cells., PMID:26701804
PDLIM1 inhibits NF-κB-mediated inflammatory signaling by sequestering the p65 subunit of NF-κB in the cytoplasm., PMID:26679095
PDZ-Reactive Peptide Activates Ephrin-B Reverse Signaling and Inhibits Neuronal Chemotaxis., PMID:26524220
Glioma invasion mediated by the p75 neurotrophin receptor (p75(NTR)/CD271) requires regulated interaction with PDLIM1., PMID:26119933
Recruitment and activation of SLK at the leading edge of migrating cells requires Src family kinase activity and the LIM-only protein 4., PMID:25882817
From hairballs to an understanding of transendothelial migration of monocytes in atherosclerosis., PMID:25142882
Lim domain binding 2: a key driver of transendothelial migration of leukocytes and atherosclerosis., PMID:24925974
Islet1 and its co-factor Ldb1 are expressed in quiescent cells of mouse intestinal epithelium., PMID:24755910
PDZ and LIM domain protein 1(PDLIM1)/CLP36 promotes breast cancer cell migration, invasion and metastasis through interaction with α-actinin., PMID:24662836
Genome-wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment., PMID:23585552
Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor., PMID:23193182
CLP36 is a negative regulator of glycoprotein VI signaling in platelets., PMID:22955732
Femtomolar Zn2+ affinity of LIM domain of PDLIM1 protein uncovers crucial contribution of protein-protein interactions to protein stability., PMID:22922308
Robust co-regulation of tyrosine phosphorylation sites on proteins reveals novel protein interactions., PMID:22851037
Isl1 and Ldb co-regulators of transcription are essential early determinants of mouse limb development., PMID:22411555
For research use only. Not for human or drug use.
