Catalog No.
YHA62401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu131-Tyr388
Predicted molecular weight
32.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43286
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Beta-1,4-galactosyltransferase 5, Beta-1,4-GalTase 5, Beta4Gal-T5, b4Gal-T5, 2.4.1.-, Beta-1,4-GalT II, Glucosylceramide beta-1,4-galactosyltransferase, 2.4.1.274, Lactosylceramide synthase, LacCer synthase, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5, B4GALT5
B4GALT5 inhibits CD8+ T-cell response by downregulating MHC-I level through ERAD pathway in PDAC., PMID:40316305
Comprehensive molecular characteristics of hepatocellular carcinoma based on multi-omics analysis., PMID:40159482
B4GALT5-deficient CHO-Lec2 cells expressing human α1,4-galactosyltransferase: A glycoengineered cell model for studying Shiga toxin receptors., PMID:40036900
GOLPH3 and GOLPH3L maintain Golgi localization of LYSET and a functional mannose 6-phosphate transport pathway., PMID:39587297
Delving into human α1,4-galactosyltransferase acceptor specificity: The role of enzyme dimerization., PMID:39111055
Downregulation of B4GALT5 attenuates cardiac fibrosis through Lumican and Akt/GSK-3β/β-catenin pathway., PMID:38081351
Circadian Genes MBOAT2/CDA/LPCAT2/B4GALT5 in the Metabolic Pathway Serve as New Biomarkers of PACA Prognosis and Immune Infiltration., PMID:37240761
Evaluation of differentially expressed genes during replication using gene expression landscape of monkeypox-infected MK2 cells: A bioinformatics and systems biology approach to understanding the genomic pattern of viral replication., PMID:36724696
SIRT2 promotes cell proliferation and migration through mediating ERK1/2 activation and lactosylceramide accumulation in prostate cancer., PMID:36082450
B4GALT5 high expression associated with poor prognosis of hepatocellular carcinoma., PMID:35410157
Circ_0009910 sponges miR-491-5p to promote acute myeloid leukemia progression through modulating B4GALT5 expression and PI3K/AKT signaling pathway., PMID:34709725
CDK7 blockade suppresses super-enhancer-associated oncogenes in bladder cancer., PMID:33905040
TERT Gene Fusions Characterize a Subset of Metastatic Leydig Cell Tumors., PMID:33741265
Expression of β-1,4-galactosyltransferases during Aging in Caenorhabditis elegans., PMID:33171474
β1,4-Galactosyltransferase V Modulates Breast Cancer Stem Cells through Wnt/β-catenin Signaling Pathway., PMID:32599982
Role of ganglioside biosynthesis genetic polymorphism in cervical cancer development., PMID:31847655
Adipocytes harbor a glucosylceramide biosynthesis pathway involved in iNKT cell activation., PMID:31051284
Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice., PMID:30114188
The Immunological Regulation Roles of Porcine β-1, 4 Galactosyltransferase V (B4GALT5) in PRRSV Infection., PMID:29546034
Downregulation of β1,4-galactosyltransferase 5 improves insulin resistance by promoting adipocyte commitment and reducing inflammation., PMID:29415997
Terminal Galactosylation and Sialylation Switching on Membrane Glycoproteins upon TNF-Alpha-Induced Insulin Resistance in Adipocytes., PMID:26537798
Understanding of altered N-glycosylation-related gene expression in recombinant Chinese hamster ovary cells subjected to elevated ammonium concentration by digital mRNA counting., PMID:25728222
High-density array comparative genomic hybridization detects novel copy number alterations in gastric adenocarcinoma., PMID:25368240
Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs., PMID:24498430
β4GalT6 is involved in the synthesis of lactosylceramide with less intensity than β4GalT5., PMID:23882130
B4GALT family mediates the multidrug resistance of human leukemia cells by regulating the hedgehog pathway and the expression of p-glycoprotein and multidrug resistance-associated protein 1., PMID:23744354
Involvement of murine β-1,4-galactosyltransferase V in lactosylceramide biosynthesis., PMID:21057870
Galactomutarotase and other galactose-related genes are rapidly induced by retinoic acid in human myeloid cells., PMID:18052213
For research use only. Not for human or drug use.
