Catalog No.
YHA53001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala629-Gly847
Predicted molecular weight
26.69 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15440
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP-binding cassette sub-family C member 5, 7.6.2.-, 7.6.2.2, Multi-specific organic anion transporter C, MOAT-C, Multidrug resistance-associated protein 5, SMRP, pABC11, ABCC5, MRP5
Hyaluronic acid-modified milk exosomes carrying ZNF516 inhibit ABCC5 and contribute to pemetrexed sensitivity in lung adenocarcinoma., PMID:40253507
Exploring the Molecular Intersection of Posterior Ocular Tuberculosis: Mycobacterium tuberculosis Proteins, Ocular Autoimmunity, and Immune Receptor Interactions., PMID:40151358
Protective role of ABCC drug subfamily resistance transporters (ABCC1-7) in intestinal inflammation., PMID:39808251
Investigating the crosstalk between ABCC4 and ABCC5 in 3T3-L1 adipocyte differentiation., PMID:39717760
The molecular mechanism of Xiaoyaosan in treating major depressive disorder: Integrated analysis of DNA methylation and RNA sequencing of the arcuate nucleus in rats., PMID:39675591
Role of ABCC5 in cancer drug resistance and its potential as a therapeutic target., PMID:39563862
Enhancing risk stratification models in localized prostate cancer by novel validated tissue biomarkers., PMID:39543244
CD133+/ABCC5+ cervical cancer cells exhibit cancer stem cell properties., PMID:39296204
Resistance to 5-fluorouracil: The molecular mechanisms of development in colon cancer cells., PMID:39241942
Association of rare and common genetic variants in MOCOS with inadequate response to allopurinol., PMID:39137147
GALNT6, GALNT14, and Gal-3 in association with GDF-15 promotes drug resistance and stemness of breast cancer via β-catenin axis., PMID:38889447
Inhibition and transport mechanisms of the ABC transporter hMRP5., PMID:38844452
COVID-19 severity gradient differentially dysregulates clinically relevant drug processing genes in nasopharyngeal swab samples., PMID:38817198
GALNT14 in association with GDF-15 promotes stemness and drug resistance through β-catenin signalling pathway in breast cancer., PMID:38796671
Development of an efficient liposomal DOX delivery formulation for HCC therapy by targeting CK2α., PMID:38651271
4-phenyl butyric acid improves hepatic ischemia/reperfusion and affects gene expression of ABC transporter Abcc5 in rats., PMID:38168520
I-CBP112 declines overexpression of ATP-binding cassette transporters and sensitized drug-resistant MDA-MB-231 and A549 cell lines to chemotherapy drugs., PMID:37913733
Activity of Lysosomal ABCC3, ABCC5 and ABCC10 is Responsible for Lysosomal Sequestration of Doxorubicin and Paclitaxel-Oregongreen488 in Paclitaxel-Resistant Cancer Cell Lines., PMID:37767694
Regulation of the ATP-binding cassette transporters ABCB1, ABCG2 and ABCC5 by nuclear receptors in porcine blood-brain barrier endothelial cells., PMID:37476954
Differential Expression of ABC Transporter Genes in Brain Vessels vs. Peripheral Tissues and Vessels from Human, Mouse and Rat., PMID:37242805
The characterization of the sensitive ovarian cancer cell lines A2780 and W1 in response to ovarian CAFs., PMID:37088000
Pomiferin targets SERCA, mTOR, and P-gp to induce autophagic cell death in apoptosis-resistant cancer cells, and reverses the MDR phenotype in cisplatin-resistant tumors in vivo., PMID:37061145
Pharmacogenetics of the Primary and Metastatic Osteosarcoma: Gene Expression Profile Associated with Outcome., PMID:36982681
Identification and characterization of ABC proteins in an important rice insect pest, Cnaphalocrocis medinalis unveil their response to Cry1C toxin., PMID:36894061
Expression analysis of novel long non-coding RNAs for invasive ductal and invasive lobular breast carcinoma cases., PMID:36868097
C-subfamily ATP binding cassette transporters extrude the calcium fluorescent probe fluo-4 from a cone photoreceptor cell line., PMID:36805766
Genetic analysis of potential biomarkers and therapeutic targets in ferroptosis from psoriasis., PMID:36685512
Anti-drug resistance, anti-inflammation, and anti-proliferation activities mediated by melatonin in doxorubicin-resistant hepatocellular carcinoma: in vitro investigations., PMID:36651944
Polymorphic renal transporters and cisplatin's toxicity in urinary bladder cancer patients: current perspectives and future directions., PMID:36650399
Enhancement of the antitumor effect of 5-fluorouracil with modulation in drug transporters expression using PI3K inhibitors in colorectal cancer cells., PMID:36574946
Circular Sponge against miR-21 Enhances the Antitumor Activity of Doxorubicin against Breast Cancer Cells., PMID:36499129
Tailored modulation of stemness and drug resistance marker characteristics in K-Ras mutant lung cancer cells via PD-L1 gene suppression., PMID:36396111
Inhibition of multidrug resistance proteins by MK571 restored the erectile function in obese mice through cGMP accumulation., PMID:36375168
The potential involvement of MRP5 pump in urethral dysfunction in streptozotocin-induced diabetic rats., PMID:36327005
[Association between single nucleotide genetic polymorphisms in ABC transporter genes with drug-resistant epilepsy in the Spanish population]., PMID:36285445
Identification and Validation of Three-Gene Signature in Lung Squamous Cell Carcinoma by Integrated Transcriptome and Methylation Analysis., PMID:36193204
Identification of ceRNA regulatory network in acute pancreatitis and acute recurrent pancreatitis., PMID:36052691
Genome-Wide Identification, Characterisation and Phylogenetic Analysis of 52 Striped Catfish (Pangasianodon hypophthalmus) ATP-Binding Cassette (ABC) Transporter Genes., PMID:35966264
Identification of Significant Secreted or Membrane-Located Proteins in Laryngeal Squamous Cell Carcinoma., PMID:35655921
Adenosine triphosphate-binding cassette subfamily C members in liver hepatocellular carcinoma: Bioinformatics-driven prognostic value., PMID:35363194
Fatty acid synthase (Fasn) inhibits the expression levels of immune response genes via alteration of alternative splicing in islet cells., PMID:35210136
FOXM1 Promotes Drug Resistance in Cervical Cancer Cells by Regulating ABCC5 Gene Transcription., PMID:35141332
MRP5 and MRP9 play a concerted role in male reproduction and mitochondrial function., PMID:35121660
FOXM1 mediates GDF-15 dependent stemness and intrinsic drug resistance in breast cancer., PMID:35066766
KCa1.1 K+ Channel Inhibition Overcomes Resistance to Antiandrogens and Doxorubicin in a Human Prostate Cancer LNCaP Spheroid Model., PMID:34948357
ABCC5 facilitates the acquired resistance of sorafenib through the inhibition of SLC7A11-induced ferroptosis in hepatocellular carcinoma., PMID:34768109
A Unified Transcriptional, Pharmacogenomic, and Gene Dependency Approach to Decipher the Biology, Diagnostic Markers, and Therapeutic Targets Associated with Prostate Cancer Metastasis., PMID:34680307
Combined BRM270 and endostatin inhibit relapse of NSCLC while suppressing lung cancer stem cell proliferation induced by endostatin., PMID:34553041
Pan-cancer analysis and single-cell analysis revealed the role of ABCC5 transporter in hepatocellular carcinoma., PMID:34494510
Inhibition of ABCC5-mediated cGMP transport by progesterone, testosterone and their analogues., PMID:34271023
For research use only. Not for human or drug use.
