Catalog No.
YHA45701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe162-Thr415
Predicted molecular weight
31.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15226
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NF-kappa-B-repressing factor, NFkB-repressing factor, NRF, Protein ITBA4, NKRF, ITBA4, NRF
Acute neuroendocrine challenge elicits enhanced cortisol response and parallel transcriptomic changes in patients with migraine., PMID:40322023
Nucleus-translocated GCLM promotes chemoresistance in colorectal cancer through a moonlighting function., PMID:39747101
E3 Ubiquitination Ligase MYLIP Mediates the NKRF/SLC25A34 Axis to Suppress Malignant Progression in Colorectal Cancer., PMID:39661280
Meta-analysis and transcriptomic analysis reveal that NKRF and ZBTB17 regulate the NF-κB signaling pathway, contributing to the shared molecular mechanisms of Alzheimer's disease and atherosclerosis., PMID:38738952
A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells., PMID:38612387
TET1 inhibits the migration and invasion of cervical cancer cells by regulating autophagy., PMID:38431880
WWP2 binds to NKRF, enhances the NF-κB signaling, and promotes malignant phenotypes of acute myeloid leukemia cells., PMID:37921219
NIFK as a potential prognostic biomarker in colorectal cancer correlating with immune infiltrates., PMID:37800782
NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R., PMID:37667861
Paeoniflorin alleviates inflammatory response in IBS-D mouse model via downregulation of the NLRP3 inflammasome pathway with involvement of miR-29a., PMID:36590561
Nuclear factor interleukin 3 (NFIL3) participates in regulation of the NF-κB-mediated inflammation and antioxidant system in Litopenaeus vannamei under ammonia-N stress., PMID:36403704
LncRNA Uc003xsl.1-Mediated Activation of the NFκB/IL8 Axis Promotes Progression of Triple-Negative Breast Cancer., PMID:34965935
MiR-192/NKRF axis confers lung cancer cell chemoresistance to cisplatin via the NF-κB pathway., PMID:34953057
RNA-Binding Proteins CLK1 and POP7 as Biomarkers for Diagnosis and Prognosis of Esophageal Squamous Cell Carcinoma., PMID:34568328
The exploration of neuroendocrine regulation of crustacean hyperglycemic hormone (CHH) on innate immunity of Litopenaeus vannamei under ammonia-N stress., PMID:34454185
miR-21a-5p Promotes Inflammation following Traumatic Spinal Cord Injury through Upregulation of Neurotoxic Reactive Astrocyte (A1) Polarization by Inhibiting the CNTF/STAT3/Nkrf Pathway., PMID:34345208
LncRNA Nron Inhibits Bone Resorption in Periodontitis., PMID:34157883
Bta-miR-101 suppresses BEFV replication via targeting NKRF., PMID:34058703
Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage., PMID:33724154
Zbtb10 transcription factor is crucial for murine cDC1 activation and cytokine secretion., PMID:33527393
RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration., PMID:33330514
Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis., PMID:32838362
Comparative Genomic Analysis of Rapidly Evolving SARS-CoV-2 Reveals Mosaic Pattern of Phylogeographical Distribution., PMID:32723797
Delineation of Clinical Manifestations of the Inherited Xq24 Microdeletion Segregating with sXCI in Mothers: Two Novel Cases with Distinct Phenotypes Ranging from UBE2A Deficiency Syndrome to Recurrent Pregnancy Loss., PMID:32485717
Upregulation of miRNA‑301a‑3p promotes tumor progression in gastric cancer by suppressing NKRF and activating NF‑κB signaling., PMID:32468020
LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer., PMID:32393270
Right and left-sided colon cancers - specificity of molecular mechanisms in tumorigenesis and progression., PMID:32293332
circ_0000638 inhibits neodymium oxide-induced bronchial epithelial cell inflammation through the miR-498-5p/NF-κB axis., PMID:32199215
Structural basis for DEAH-helicase activation by G-patch proteins., PMID:32179686
Integrated functional genomic analyses of Klinefelter and Turner syndromes reveal global network effects of altered X chromosome dosage., PMID:32071206
Proteomic Analysis of Human Serum from Patients with Chronic Kidney Disease., PMID:32046176
Full-length NF-κB repressing factor contains an XRN2 binding domain., PMID:32011671
MiR-29b expression is altered in crescent formation of HSPN and accelerates Ang II-induced mesangial cell activation., PMID:31630337
miR-301a Regulates Inflammatory Response to Japanese Encephalitis Virus Infection via Suppression of NKRF Activity., PMID:31527198
Inhibition of microRNA‑124‑3p protects against acute myocardial infarction by suppressing the apoptosis of cardiomyocytes., PMID:31432169
Effects of crustacean hyperglycemic hormone (CHH) on regulation of hemocyte intracellular signaling pathways and phagocytosis in white shrimp Litopenaeus vannamei., PMID:31330256
Data on molecular characterization and expression profiles of the NF-κB repressing factor gene in red sea bream (Pagrus major)., PMID:31193988
MiR-802 causes nephropathy by suppressing NF-κB-repressing factor in obese mice and human., PMID:30729676
Homoharringtonine deregulates MYC transcriptional expression by directly binding NF-κB repressing factor., PMID:30659143
Increased expression of mir-301a in PBMCs of patients with relapsing-remitting multiple sclerosis is associated with reduced NKRF and PIAS3 expression levels and disease activity., PMID:30316680
Plastin 3 influences bone homeostasis through regulation of osteoclast activity., PMID:30204862
Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein., PMID:29261807
Identification, characterization, and function analysis of the NF-κB repressing factor (NKRF) gene from Litopenaeus vannamei., PMID:28564581
Noncanonical NF-κB mediates the Suppressive Effect of Neutrophil Elastase on IL-8/CXCL8 by Inducing NKRF in Human Airway Smooth Muscle., PMID:28322300
The G-patch protein NF-κB-repressing factor mediates the recruitment of the exonuclease XRN2 and activation of the RNA helicase DHX15 in human ribosome biogenesis., PMID:28115624
Human NF-κB repressing factor acts as a stress-regulated switch for ribosomal RNA processing and nucleolar homeostasis surveillance., PMID:28096332
Atlantic salmon populations reveal adaptive divergence of immune related genes - a duplicated genome under selection., PMID:27515098
Spica prunellae and its marker compound rosmarinic acid induced the expression of efflux transporters through activation of Nrf2-mediated signaling pathway in HepG2 cells., PMID:27422165
The role of melatonin membrane receptors in melatonin-dependent oxytocin secretion from the rat hypothalamo-neurohypophysial system - an in vitro and in vivo approach., PMID:26884304
NF-κB-repressing factor phosphorylation regulates transcription elongation via its interactions with 5'→3' exoribonuclease 2 and negative elongation factor., PMID:26340924
For research use only. Not for human or drug use.
