Catalog No.
YHA28201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly21-Leu319
Predicted molecular weight
36.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14734
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Acyl-coenzyme A thioesterase 8, Acyl-CoA thioesterase 8, 3.1.2.1, 3.1.2.11, 3.1.2.2, 3.1.2.3, 3.1.2.5, Choloyl-coenzyme A thioesterase, 3.1.2.27, HIV-Nef-associated acyl-CoA thioesterase, Peroxisomal acyl-CoA thioesterase 2, PTE-2, Peroxisomal acyl-coenzyme A thioester hydrolase 1, PTE-1, Peroxisomal long-chain acyl-CoA thioesterase 1, Thioesterase II, hACTE-III, hACTEIII, hTE, ACOT8, ACTEIII, PTE1
Acyl-CoA Thioesterase 8 (ACOT8) is a Poor Prognostic Biomarker in Breast Cancer., PMID:39188355
Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress., PMID:37902629
Substantial downregulation of mitochondrial and peroxisomal proteins during acute kidney injury revealed by data-independent acquisition proteomics., PMID:37775337
Substantial Downregulation of Mitochondrial and Peroxisomal Proteins during Acute Kidney Injury revealed by Data-Independent Acquisition Proteomics., PMID:36865241
Integrated Omics analysis of pig muscle metabolism under the effects of dietary Chlorella vulgaris and exogenous enzymes., PMID:36216870
Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0., PMID:35516420
Dietary soya saponin improves the lipid metabolism and intestinal health of laying hens., PMID:35172236
Acyl-CoA Thioesterase 8 and 11 as Novel Biomarkers for Clear Cell Renal Cell Carcinoma., PMID:33362855
The Study of the Response of Fat Metabolism to Long-Term Energy Stress Based on Serum, Fatty Acid and Transcriptome Profiles in Yaks., PMID:32645922
Transcriptome analysis of golden pompano (Trachinotus ovatus) liver indicates a potential regulatory target involved in HUFA uptake and deposition., PMID:31733535
Physiological relevance of ACOT8-Nef interaction in HIV infection., PMID:31179598
Orlistat Displays Antitumor Activity and Enhances the Efficacy of Paclitaxel in Human Hepatoma Hep3B Cells., PMID:30667213
Dietary Genistein Alleviates Lipid Metabolism Disorder and Inflammatory Response in Laying Hens With Fatty Liver Syndrome., PMID:30405443
Molecular characterization of HIV-1 Nef and ACOT8 interaction: insights from in silico structural predictions and in vitro functional assays., PMID:26927806
AP-2 Is the Crucial Clathrin Adaptor Protein for CD4 Downmodulation by HIV-1 Nef in Infected Primary CD4+ T Cells., PMID:26423947
Fatty acid metabolic enzyme acyl-CoA thioesterase 8 promotes the development of hepatocellular carcinoma., PMID:24788990
Acyl-CoA thioesterase 8 is a specific protein related to nodal metastasis and prognosis of lung adenocarcinoma., PMID:23540296
Crystallization of the acyl-CoA thioesterase TesB from Yersinia pestis., PMID:23385765
The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism., PMID:22465940
Comparative proteomic analysis of proteins influenced by melanin-concentrating hormone and melanin-concentrating hormone receptor 2 interaction., PMID:20340065
The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes., PMID:16141203
Overexpression of human acyl-CoA thioesterase upregulates peroxisome biogenesis., PMID:15194431
Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions., PMID:10799608
Subcellular localization and PKC-dependent regulation of the human lysophospholipase A/acyl-protein thioesterase in WISH cells., PMID:10760470
Characterization of a human MHC class III region gene product with S-thioesterase activity., PMID:10417332
Identification of peroxisomal acyl-CoA thioesterases in yeast and humans., PMID:10092594
Binding of HIV-1 Nef to a novel thioesterase enzyme correlates with Nef-mediated CD4 down-regulation., PMID:9153233
For research use only. Not for human or drug use.
