Catalog No.
YHA22801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu273-Gly608
Predicted molecular weight
39.74 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14576
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cytoplasmic dynein 1 intermediate chain 1, Cytoplasmic dynein intermediate chain 1, Dynein intermediate chain 1, cytosolic, DH IC-1, DYNC1I1, DNCI1, DNCIC1
RNA sequencing and genome-wide association analysis reveal key genes responsible for different feather colors in Youjiang goose., PMID:40424883
Survival prediction in patients with head and neck squamous cell carcinoma and novel mechanistic insights of S100A8/A9., PMID:39546127
DYNC1I1 acts as a promising prognostic biomarker and is correlated with immune infiltration in head and neck squamous cell carcinoma., PMID:38072235
Split Hand-Foot and Deafness in a Patient with 7q21.13-q21.3 Deletion Not Including the DLX5/6 Genes., PMID:37628577
Pain sensitivity related to gamma oscillation of parvalbumin interneuron in primary somatosensory cortex in Dync1i1-/- mice., PMID:37257662
Opsin 3 mediates UVA-induced keratinocyte supranuclear melanin cap formation., PMID:36869204
HTT (huntingtin) and RAB7 co-migrate retrogradely on a signaling LAMP1-containing late endosome during axonal injury., PMID:36048753
Whole-exome sequencing and adrenocorticotropic hormone therapy in individuals with infantile spasms., PMID:35830182
Potential Target Analysis of Triptolide Based on Transcriptome-Wide m6A Methylome in Rheumatoid Arthritis., PMID:35401168
CircCCNB1 silencing acting as a miR-106b-5p sponge inhibited GPM6A expression to promote HCC progression by enhancing DYNC1I1 expression and activating the AKT/ERK signaling pathway., PMID:35002514
In vitro transcriptome response to propolis in differentiated SH-SY5Y neurons., PMID:34730243
Bioinformatics analysis identifies DYNC1I1 as prognosis marker in male patients with liver hepatocellular carcinoma., PMID:34679093
Detecting Prognosis Risk Biomarkers for Colon Cancer Through Multi-Omics-Based Prognostic Analysis and Target Regulation Simulation Modeling., PMID:32528533
Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes., PMID:32513296
[Clinical feature and pathogenic analysis of a fetus with split hand-foot malformation]., PMID:32219838
Localization of GPSM2 in the Nucleus of Invasive Breast Cancer Cells Indicates a Poor Prognosis., PMID:32195179
TNPO2 operates downstream of DYNC1I1 and promotes gastric cancer cell proliferation and inhibits apoptosis., PMID:31605449
A novel mutation (c.1010G>T; p.R337L) in TP63 as a cause of split-hand/foot malformation with hypodontia., PMID:31420900
Plin3 protects against alcoholic liver injury by facilitating lipid export from the endoplasmic reticulum., PMID:31119787
Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma., PMID:30250299
Dynactin is involved in Lewy body pathology., PMID:30215870
Dynein binds and stimulates axonal motility of the endosome adaptor and NEEP21 family member, calcyon., PMID:28734834
Cellular model of neuronal atrophy induced by DYNC1I1 deficiency reveals protective roles of RAS-RAF-MEK signaling., PMID:27510948
A novel description of a syndrome consisting of 7q21.3 deletion including DYNC1I1 with preserved DLX5/6 without ectrodactyly: a case report., PMID:27291887
Exonic enhancers: proceed with caution in exome and genome sequencing studies., PMID:26856702
Absent expression of the osteoblast-specific maternally imprinted genes, DLX5 and DLX6, causes split hand/split foot malformation type I., PMID:25332435
Deletions of exons with regulatory activity at the DYNC1I1 locus are associated with split-hand/split-foot malformation: array CGH screening of 134 unrelated families., PMID:25231166
Interaction of SQSTM1 with the motor protein dynein--SQSTM1 is required for normal dynein function and trafficking., PMID:25015291
Next generation sequencing of chromosomal rearrangements in patients with split-hand/split-foot malformation provides evidence for DYNC1I1 exonic enhancers of DLX5/6 expression in humans., PMID:24459211
Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions., PMID:23475693
Coding exons function as tissue-specific enhancers of nearby genes., PMID:22442009
Digital karyotyping reveals probable target genes at 7q21.3 locus in hepatocellular carcinoma., PMID:21767414
Genetic variation associated with bortezomib-induced peripheral neuropathy., PMID:21228734
Mouse cytoplasmic dynein intermediate chains: identification of new isoforms, alternative splicing and tissue distribution of transcripts., PMID:20657784
For research use only. Not for human or drug use.
