Catalog No.
YHA01101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
[Asp2-Leu37] & [Leu57-Ile87] & [Gly107-Asp132]
Predicted molecular weight
26.15 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A6NNB3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interferon-induced transmembrane protein 5, Bone-restricted interferon-induced transmembrane protein-like protein, BRIL, Dispanin subfamily A member 1, DSPA1, IFITM5
Osteogenesis imperfecta type V: About a clinical case., PMID:40379599
Genetic landscape and phenotypic spectrum of osteogenesis imperfecta in the Kazakhstani pediatric population., PMID:40175636
Brittle, but not boring: a fresh look at osteogenesis imperfecta type V., PMID:40068302
An inducible mouse model of osteogenesis imperfecta type V reveals aberrant osteogenesis caused by Ifitm5 c.-14C>T mutation., PMID:39908237
Identification of human cranio-maxillofacial skeletal stem cells for mandibular development., PMID:39742474
Rare diseases: a challenge in paediatric dentistry., PMID:39212455
Update on the Genetics of Osteogenesis Imperfecta., PMID:39127989
Genotype and Phenotype Correlation of Patients with Osteogenesis Imperfecta., PMID:39025364
Effectiveness of whole exome sequencing analyses in the molecular diagnosis of osteogenesis imperfecta., PMID:38953412
The IFITM5 mutation in osteogenesis imperfecta type V is associated with an ERK/SOX9-dependent osteoprogenitor differentiation defect., PMID:38885336
Exome sequencing identified mutations in the WNT1 and COL1A2 genes in osteogenesis imperfecta cases., PMID:38536562
Echocardiographic abnormalities and joint hypermobility in Chinese patients with Osteogenesis imperfecta., PMID:38475860
Role of interferon-induced transmembrane protein family in cancer progression: a special focus on pancreatic cancer., PMID:38472606
Weighted burden analysis of rare coding variants in 470,000 exome-sequenced UK Biobank participants characterises effects on hyperlipidaemia risk., PMID:38454133
Role of IFITM2 in osteogenic differentiation of C3H10T1/2 mesenchymal stem cells., PMID:38404731
Association of Antenatal Evaluations with Postmortem and Genetic Findings in the Series of Fetal Osteogenesis Imperfecta., PMID:38346409
Transcriptome Sequencing of Gingival Tissues from Impacted Third Molars Patients Reveals the Alterations of Gene Expression., PMID:38178683
Assessing type I collagen expression and quality in cellular models of osteogenesis imperfecta., PMID:38014644
The IFITM5 Ser40Leu variant can manifest as prenatal Caffey disease., PMID:37799085
DMP1 and IFITM5 Regulate Osteogenic Differentiation of MC3T3-E1 on PEO-Treated Ti-6Al-4V-Ca2+/Pi surface., PMID:36802481
Abnormal signal pathways and tumor heterogeneity in osteosarcoma., PMID:36759884
Genetic analysis of osteogenesis imperfecta in a large Brazilian cohort., PMID:36709916
Identification of novel prognostic biomarkers for osteosarcoma: a bioinformatics analysis of differentially expressed genes in the mesenchymal stem cells from single-cell sequencing data set., PMID:36388032
Does the c.-14C>T Mutation in the IFITM5 Gene Provide Identical Phenotypes for Osteogenesis Imperfecta Type V? Data from Russia and a Literature Review., PMID:36289625
Alterations of bone material properties in growing Ifitm5/BRIL p.S42 knock-in mice, a new model for atypical type VI osteogenesis imperfecta., PMID:35654352
Genotype-Phenotype Relationship and Follow-up Analysis of a Chinese Cohort With Osteogenesis Imperfecta., PMID:35550181
The Osteogenesis Imperfecta Type V Mutant BRIL/IFITM5 Promotes Transcriptional Activation of MEF2, NFATc, and NR4A in Osteoblasts., PMID:35216266
Osteogenesis Imperfecta: Search for Mutations in Patients from the Republic of Bashkortostan (Russia)., PMID:35052464
Specific Characteristic of Hyperplastic Callus in a Larger Cohort of Osteogenesis Imperfecta Type V., PMID:34988594
Osteogenesis imperfecta in 140 Turkish families: Molecular spectrum and, comparison of long-term clinical outcome of those with COL1A1/A2 and biallelic variants., PMID:34902613
An Unusual Presentation of Osteogenesis Imperfecta: A Case Report., PMID:34807880
Integrative overview of IFITMs family based on Bioinformatics analysis., PMID:34466338
A Novel IFITM5 Variant Associated with Phenotype of Osteoporosis with Calvarial Doughnut Lesions: A Case Report., PMID:34156493
Calvaria Bone Transcriptome in Mouse Models of Osteogenesis Imperfecta., PMID:34069814
Osteogenesis Imperfecta: Mechanisms and Signaling Pathways Connecting Classical and Rare OI Types., PMID:34007986
Genetic analysis in Japanese patients with osteogenesis imperfecta: Genotype and phenotype spectra in 96 probands., PMID:33939306
Coalescing expansile skeletal disease: Delineation of an extraordinary osteopathy involving the IFITM5 mutation of osteogenesis imperfecta type V., PMID:33360005
Effect of immunosuppressants on a mouse model of osteogenesis imperfecta type V harboring a heterozygous Ifitm5 c.-14C > T mutation., PMID:33273604
A novel variant of the IFITM5 gene within the 5'-UTR causes neonatal transverse clavicular fracture: Expanding the genetic spectrum., PMID:32383316
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins., PMID:32221310
The molecular landscape of osteogenesis imperfecta in a Brazilian tertiary service cohort., PMID:32123938
Osteogenesis imperfecta in a male holstein calf associated with a possible oligogenic origin., PMID:31980012
The IFITM protein family in adaptive immunity., PMID:31792954
[Prenatal gene diagnosis of 200 fetuses at high risk of osteogenesis imperfect]., PMID:31715670
Bruck syndrome 2 variant lacking congenital contractures and involving a novel compound heterozygous PLOD2 mutation., PMID:31472299
Analysis of IFITM-IFITM Interactions by a Flow Cytometry-Based FRET Assay., PMID:31398796
Comprehensive genetic analyses using targeted next-generation sequencing and genotype-phenotype correlations in 53 Japanese patients with osteogenesis imperfecta., PMID:31363794
Altered gene expression profiles of the MDA5 signaling pathway in peripheral blood lymphocytes of chickens infected with avian reovirus., PMID:31273469
Expanding the Clinical Spectrum of Osteogenesis Imperfecta Type V: 13 Additional Patients and Review., PMID:31244780
IFITM5 pathogenic variant causes osteogenesis imperfecta V with various phenotype severity in Ukrainian and Vietnamese patients., PMID:31159867
For research use only. Not for human or drug use.
