Catalog No.
EHD19402
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
IL7R [Met1-Asp239] & TSLPR [Gln23-Lys231]
Predicted molecular weight
26.22 kDa & 25.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P16871 & Q9HC73
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IL7R, Interleukin-7 receptor subunit alpha, IL-7R-alpha, IL-7 receptor subunit alpha, CD127, CDw127, IL-7R subunit alpha, IL-7RA, Cytokine receptor-like 2, CRLF2, CRL2, Thymic stromal lymphopoietin protein receptor, Cytokine receptor-like factor 2, TSLPR, ILXR, IL-XR, TSLP receptor
Predicting T-ALL response to pre-TCR and IL-7R coinhibition., PMID:40504516
Biomarker analysis and treatment dynamics following preoperative ipilimumab plus nivolumab in locally advanced urothelial cancer from the phase 1B NABUCCO study., PMID:40489082
Heterogeneous characteristics of γδ T cells in peripheral blood of diffuse large B-cell lymphoma., PMID:40483533
Gene-Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies., PMID:40462597
Centralized rapid genetic diagnosis of combined immunodeficiency in Japan., PMID:40457861
Transcriptomic profiling of cytomegalovirus infection in cardiac transplantation: proof-of-concept for a new strategy in tissue markers application., PMID:40453097
Unveiling the role of IL7R in metabolism-associated fatty liver disease leading to hepatocellular carcinoma through transcriptomic and machine learning approaches., PMID:40408005
IL7-IL7R Interaction Mediates Fibroblast-Driven Macrophage-to-Osteoclast Differentiation in Periodontitis., PMID:40386183
The Human Bone Marrow May Offer an IL-15-Dependent Survival Niche for EOMES+ Tr1-Like Cells., PMID:40375822
Interleukin-7 enhances recruitment of MDSCs by regulating MCP-1 via JAK1/STAT3 signaling pathway in non-small cell lung cancer., PMID:40374882
Leveraging Subjective Parameters and Biomarkers in Machine Learning Models: The Feasibility of lnc-IL7R for Managing Emphysema Progression., PMID:40361983
Research on the functions and potential mechanisms of STAT3 in chronic myelogenous leukemia., PMID:40353923
Epigenome-Wide DNA Methylation Profiling of Peripheral Blood Shows Lymphocyte Dysfunction in Children with Kawasaki Disease., PMID:40340576
Identification and validation of diagnostic markers and drugs for pediatric bronchopulmonary dysplasia based on integrating bioinformatics and molecular docking analysis., PMID:40333951
Comparative Efficacy of Interleukin-7 and -15 Blockade in Alleviating Experimental Chronic Uveitis and Suppressing Pathogenic Memory CD4+ T Cells., PMID:40323267
IL-7 in autoimmune diseases: mechanisms and therapeutic potential., PMID:40313966
Bone marrow mesenchymal stem cells alleviate liver fibrosis after rat liver transplantation through JAK1/STAT5 pathway., PMID:40312752
The impact of inflammation and iron metabolism on gene expression alterations in ischemic stroke: a bioinformatics approach., PMID:40307317
Identification of M2 macrophage-related genes associated with diffuse large B-cell lymphoma via bioinformatics and machine learning approaches., PMID:40302006
Establishment and evaluation cuproptosis-related gene signature for predicting the prognosis and immunotherapy response of hepatocellular carcinoma., PMID:40296031
Construction of a tumor immune microenvironment-related risk scoring model for prognosis of hepatocellular carcinoma., PMID:40265593
The single-cell immune landscape of HIV-associated aggressive B-cell lymphoma., PMID:40265092
Genetics of circulating proteins in newborn babies at high risk of type 1 diabetes., PMID:40263317
Identification of a Gene Expression Signature to Predict the Risk of Abdominal Aortic Aneurysm in Psoriasis Patients., PMID:40260094
Deficiency of IL-7R attenuates abdominal aortic aneurysms in mice by inhibiting macrophage polarization towards M1 phenotype through the NF-κB pathway., PMID:40240976
Stem-like CD8+ T cells preserve HBV-specific responses in HBV/HIV co-infection., PMID:40236431
A Spatial Multi-Omic Framework Identifies Gliomas Permissive to TIL Expansion., PMID:40236001
Construction of enhanced MRI-based radiomics models using machine learning algorithms for non-invasive prediction of IL7R expression in high-grade gliomas and its prognostic value in clinical practice., PMID:40165301
Frequency and prognostic value of unconventional genetic subtypes in paediatric and young adult B-cell precursor acute lymphoblastic leukaemia in Taiwan., PMID:40132994
CD4+ anti-TGF-β CAR T cells and CD8+ conventional CAR T cells exhibit synergistic antitumor effects., PMID:40107245
Pre-B-cell leukemia transcription factor 1 contributes to liver fibrosis by enabling IL-7 signaling in HSC., PMID:40080840
The transcription factor RORα is required for the development of type 1 innate lymphoid cells in adult bone marrow., PMID:40079843
Integrative approach to decipher pharmacological mechanism of Cinnamomum zeylanicum essential oil in prostate cancer., PMID:40072751
LAMP2-FLOT2 interaction enhances autophagosome-lysosome fusion to protect the septic heart in response to ILC2., PMID:40066518
MYC networks associate with decreased CD8 T-cell presence in diffuse large B-cell lymphoma and may be addressed by the synergistic combination of AZD4573 and Selinexor - a preliminary analysis., PMID:40064656
The contribution of genetic determinants of blood gene expression and splicing to molecular phenotypes and health outcomes., PMID:40038547
Cytotoxic KLRG1+ IL-7R- effector CD8+ T cells distinguish kidney transplant recipients controlling cytomegalovirus reactivation., PMID:40028342
Transcriptomic and biometric parameters analysis in rainbow trout (Oncorhynchus mykiss) challenged with viral hemorrhagic septicemia virus (VHSV)., PMID:40021981
Divergent adaptation to highland and tropical environments in Bolivian Creole cattle., PMID:40015466
Melatonin Modulates ZAP70 and CD40 Transcripts via Histone Modifications in Canine Ileum Epithelial Cells., PMID:40005847
Translating Biomarker Research into Clinical Practice in Orthopaedic Trauma: A Systematic Review., PMID:40004859
Integrated Metabolomic and Transcriptomic Analysis Revealed the Mechanism of BHPF Exposure in Endometrium., PMID:39997915
The ClinGen Severe Combined Immunodeficiency Disease Variant Curation Expert Panel: Specifications for classification of variants in ADA , DCLRE1C , IL2RG , IL7R , JAK3 , RAG1 , and RAG2., PMID:39990552
Single-Cell Transcriptomic Profile of Innate Cell Populations in Mesenteric Lymph Nodes of Inflammatory Bowel Disease Patients., PMID:39982469
Genome-wide KAS-Seq mapping of leukocytes in ischemia-reperfusion model reveals IL7R as a potential therapeutic target for ischemia-reperfusion injury., PMID:39979392
Surface pTα expression predicts LCK activation and preclinical synergy of LCK and JAK coinhibition in adult T-ALL., PMID:39977715
Antiviral metabolites from Passiflora edulis: An in vitro, phytochemical, and computational studies., PMID:39945526
Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker., PMID:39931173
Renal Tubular Epithelial Cell-Derived IL-7 Drives Expansion and Protective Effects of Double-Negative T Cells in Acute Kidney Injury., PMID:39912351
A minimal gene set characterizes TIL specific for diverse tumor antigens across different cancer types., PMID:39900903
For research use only. Not for human or drug use.
