Catalog No.
YVV33002
Expression system
E. coli
Species
JC polyomavirus (JCPyV) (JCV)
Protein length
Met1-Leu354
Predicted molecular weight
42.61 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99FM1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Capsid protein VP1, VP1
Nonclinical and clinical characterization of MAU868, a novel human-derived monoclonal neutralizing antibody targeting BK polyomavirus VP1., PMID:38996969
IgG Seroreactivites to Viral Capsid Protein VP1 of JC and BK Polyomaviruses in Children at Early Ages with Special Reference to Parental Cofactors., PMID:37892308
Designing a Multi-Epitope Subunit Vaccine against VP1 Major Coat Protein of JC Polyomavirus., PMID:37514998
Seroprevalence of polyomaviruses BK and JC in Finnish women and their spouses followed-up for three years., PMID:36650213
T cell deficiency precipitates antibody evasion and emergence of neurovirulent polyomavirus., PMID:36341713
The oncogenic roles of JC polyomavirus in cancer., PMID:36212474
The Inhibition of DNA Viruses by the Amphibian Antimicrobial Peptide Temporin G: A Virological Study Addressing HSV-1 and JPCyV., PMID:35806198
Risk Assessment of Progressive Multifocal Leukoencephalopathy in Multiple Sclerosis Patients during 1 Year of Ocrelizumab Treatment., PMID:34578264
Colorectal Carcinoma Affected Patients Are Significantly Poor Responders Against the Oncogenic JC Polyomavirus., PMID:34113338
JCPyV VP1 Mutations in Progressive MultifocalLeukoencephalopathy: Altering Tropismor Mediating Immune Evasion?, PMID:33053912
Human iPS cell-derived astrocytes support efficient replication of progressive multifocal leukoencephalopathy-type JC polyomavirus., PMID:33008586
Antibody escape by polyomavirus capsid mutation facilitates neurovirulence., PMID:32940605
Investigation of simian virus 40 (SV40) and human JC, BK, MC, KI, and WU polyomaviruses in glioma., PMID:32124265
Which is the best PML risk stratification strategy in natalizumab-treated patients affected by multiple sclerosis?, PMID:32087593
Specific antibodies reacting to JC polyomavirus capsid protein mimotopes in sera from multiple sclerosis and other neurological diseases-affected patients., PMID:32012272
Molecular epidemiology of JC polyomavirus in HIV-infected patients and healthy individuals from Iran., PMID:31364012
Establishment of COS-JC cells persistently producing archetype JC polyomavirus., PMID:29932215
Characterization of BK Polyomaviruses from Kidney Transplant Recipients Suggests a Role for APOBEC3 in Driving In-Host Virus Evolution., PMID:29746834
ERK Is a Critical Regulator of JC Polyomavirus Infection., PMID:29321332
Analysis of variability of urinary excreted JC virus strains in patients infected with HIV and healthy donors., PMID:29243131
Archetype JC Polyomavirus (JCPyV) Prevails in a Rare Case of JCPyV Nephropathy and in Stable Renal Transplant Recipients With JCPyV Viruria., PMID:28968776
Multiplex detection in tonsillar tissue of all known human polyomaviruses., PMID:28595595
Single-Molecule Sequencing Revealing the Presence of Distinct JC Polyomavirus Populations in Patients With Progressive Multifocal Leukoencephalopathy., PMID:28453853
Specific IgG Antibodies React to Mimotopes of BK Polyomavirus, a Small DNA Tumor Virus, in Healthy Adult Sera., PMID:28321224
Tracing Males From Different Continents by Genotyping JC Polyomavirus in DNA From Semen Samples., PMID:27859215
Polyomaviruses., PMID:27726799
Divergent Trends of Anti-JCPyV Serum Reactivity and Neutralizing Activity in Multiple Sclerosis (MS) Patients during Treatment with Natalizumab., PMID:27164128
Recombinant VLP-Z of JC Polyomavirus: A Novel Vector for Targeting Gene Delivery., PMID:26909539
Broadly neutralizing human monoclonal JC polyomavirus VP1-specific antibodies as candidate therapeutics for progressive multifocal leukoencephalopathy., PMID:26400911
Characterization of Rabbit Antibodies Against the Immunogenic JC Polyomavirus Peptide JCPyV_VP2_167-15mer., PMID:26075335
Characterization of self-assembled virus-like particles of Merkel cell polyomavirus., PMID:25671590
Modulation of a pore in the capsid of JC polyomavirus reduces infectivity and prevents exposure of the minor capsid proteins., PMID:25609820
Small-molecule inhibitors of JC polyomavirus infection., PMID:25522925
Antibodies reacting with JCPyV_VP2 _167-15mer as a novel serological marker for JC polyomavirus infection., PMID:25273879
Antiviral effects of artesunate on JC polyomavirus replication in COS-7 cells., PMID:25155602
Cloning of the first human anti-JCPyV/VP1 neutralizing monoclonal antibody: epitope definition and implications in risk stratification of patients under natalizumab therapy., PMID:24909571
Progressive multifocal leukoencephalopathy-associated mutations in the JC polyomavirus capsid disrupt lactoseries tetrasaccharide c binding., PMID:23760462
Serological cross-reactivity between human polyomaviruses., PMID:23650080
JC polyomavirus reactivation is not associated with herpes zoster., PMID:16808330
Characterization of the VP1 loop mutations widespread among JC polyomavirus isolates associated with progressive multifocal leukoencephalopathy., PMID:15964545
New sequence polymorphisms in the outer loops of the JC polyomavirus major capsid protein (VP1) possibly associated with progressive multifocal leukoencephalopathy., PMID:15958683
Detection of JC polyomavirus DNA sequences and cellular localization of T-antigen and agnoprotein in oligodendrogliomas., PMID:12429619
For research use only. Not for human or drug use.
