Catalog No.
YHC04001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln25-Ser68
Predicted molecular weight
20.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P03928
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP synthase protein 8, A6L, F-ATPase subunit 8, MT-ATP8, ATP8, ATPASE8, MTATP8
Cadmium Exposure Disrupts Uterine Energy Metabolism and Coagulation Homeostasis During Labor in Institute of Cancer Research Mice: Insights from Transcriptomic Analysis., PMID:40422915
Natural History of Patients With Mitochondrial ATPase Deficiency Due to Pathogenic Variants of MT-ATP6 and MT-ATP8., PMID:40112238
A high-resolution bovine mitochondrial co-expression network., PMID:39898529
Bladder cancer associated with elevated heavy metals: Investigation of probable carcinogenic pathways through mitochondrial dysfunction, oxidative stress and mitogen-activated protein kinase., PMID:39379209
Novel 4th-generation phytase improves broiler growth performance and reduces woody breast severity through modulation of muscle glucose uptake and metabolism., PMID:38559573
Ribosome Profiling and Mass Spectrometry Reveal Widespread Mitochondrial Translation Defects in a Striatal Cell Model of Huntington Disease., PMID:38447791
Variants in Human ATP Synthase Mitochondrial Genes: Biochemical Dysfunctions, Associated Diseases, and Therapies., PMID:38396915
Jianpi-Yangxue-Jiedu decoction improves the energy metabolism of psoriasis mice by regulating the electron transfer of oxidative phosphorylation., PMID:38184027
Exploring the role of PRDX4 in the development of uterine corpus endometrial carcinoma., PMID:38177789
A systems biology approach to pathogenesis of gastric cancer: gene network modeling and pathway analysis., PMID:37482618
Heart failure in patients is associated with downregulation of mitochondrial quality control genes., PMID:37403271
Analysis of MT-ATP8 gene variants reported in patients by modeling in silico and in yeast model organism., PMID:37340059
Identification of a New RNA and Protein Integrated Biomarker Panel Associated with Kidney Function Impairment in DKD: Translational Implications., PMID:37298364
Mitogenomic Codon Usage Patterns of Superfamily Certhioidea (Aves, Passeriformes): Insights into Asymmetrical Bias and Phylogenetic Implications., PMID:36611705
A lack of a definite correlation between male sub-fertility and single nucleotide polymorphisms in sperm mitochondrial genes MT-CO3, MT-ATP6 and MT-ATP8., PMID:36066780
Pan-TRK Immunohistochemistry and NTRK Gene Fusions in Primary Carcinomas of the Liver., PMID:35587529
Autophagy deficiency abolishes liver mitochondrial DNA segregation., PMID:35220898
Next-generation sequencing of the whole mitochondrial genome identifies functionally deleterious mutations in patients with multiple sclerosis., PMID:35130313
A Mitochondrial Polymorphism Alters Immune Cell Metabolism and Protects Mice from Skin Inflammation., PMID:33498298
Homoplasmic deleterious MT-ATP6/8 mutations in adult patients., PMID:32858252
Similarities and dissimilarities of codon usage in mitochondrial ATP genes among fishes, aves, and mammals., PMID:31958218
Specific PCR method for detection of species origin in biochemical drugs via primers for the ATPase 8 gene by electrophoresis., PMID:31428871
Mitochondrial DNA sequencing reveals association of variants and haplogroup M33a2'3 with High altitude pulmonary edema susceptibility in Indian male lowlanders., PMID:31358833
Genetic Analysis of Small-Subunit Ribosomal RNA, Internal Transcribed Spacer 2, and ATP Synthase Subunit 8 of Trichuris trichiura Ancient DNA Retrieved from the 15th to 18th Century Joseon Dynasty Mummies' Coprolites from Korea., PMID:31310584
Whole mitochondria genome mutational spectrum in occupationally exposed lead subjects., PMID:31029642
Down-regulation of mitochondrial NADH and cytochrome b gene associated with high tumor stages in head and neck squamous cell carcinoma., PMID:30658318
[Molecular bases of diseases caused by mutations in genes encoding subunits of ATP synthase]., PMID:30656915
Mitochondrial DNA Mutations Associated with Type 2 Diabetes Mellitus in Chinese Uyghur Population., PMID:29208909
Mitochondrial gene polymorphism is associated with gut microbial communities in mice., PMID:29127319
Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs)., PMID:28978032
Novel non-neutral mitochondrial DNA mutations found in childhood acute lymphoblastic leukemia., PMID:28708239
Polymorphism in Murine mtATP8 Gene Correlates with Decreased Reactive Oxygen Species in Aging Hematopoietic Cells., PMID:27815458
Leber Hereditary Optic Neuropathy: Visual Recovery in a Patient With the Rare m.3890G>A Point Mutation., PMID:27798429
Proteomic profiling reveals oxidative phosphorylation pathway is suppressed in longissimus dorsi muscle of weaned piglets fed low-protein diet supplemented with limiting amino acids., PMID:27590855
A novel mutation m.8561C>G in MT-ATP6/8 causing a mitochondrial syndrome with ataxia, peripheral neuropathy, diabetes mellitus, and hypergonadotropic hypogonadism., PMID:27502083
Methylmercury-induced developmental toxicity is associated with oxidative stress and cofilin phosphorylation. Cellular and human studies., PMID:27241350
Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis., PMID:27069868
Mutational analysis in patients with neuromuscular disorders: Detection of mitochondrial deletion and double mutations in the MT-ATP6 gene., PMID:26993169
Rapidly progressive infantile cardiomyopathy with mitochondrial respiratory chain complex V deficiency due to loss of ATPase 6 and 8 protein., PMID:26803244
Polymorphisms in the mitochondrially encoded ATP synthase 8 gene are associated with susceptibility to bullous pemphigoid in the German population., PMID:25941154
Mitochondrial complex I and V gene polymorphisms associated with breast cancer in mizo-mongloid population., PMID:25896597
Mitochondrial genetic variants identified to be associated with posttraumatic stress disorder., PMID:25756807
Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation., PMID:25588698
Novel mitochondrial mutations in the ATP6 and ATP8 genes in patients with breast cancer., PMID:25110199
1,8-dihydroxy-3-acetyl-6-methyl-9,10 anthraquinone exhibits a potent radiosensitizing effect with induced oncosis in human nasopharyngeal carcinoma cells., PMID:24912934
Common and Novel TMEM70 Mutations in a Cohort of Italian Patients with Mitochondrial Encephalocardiomyopathy., PMID:24740313
Evidence for the presence of somatic mitochondrial DNA mutations in right atrial appendage tissues of coronary artery disease patients., PMID:24604425
Novel mutations in ATPase 8, ND1 and ND5 genes associated with peripheral neuropathy of diabetes., PMID:24456990
Mitochondrial DNA profiling via genomic analysis in mesial temporal lobe epilepsy patients with hippocampal sclerosis., PMID:24440288
Episodic weakness due to mitochondrial DNA MT-ATP6/8 mutations., PMID:24153443
For research use only. Not for human or drug use.
