Catalog No.
VHE20501
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Target
Bispecific, Serine/threonine-protein kinase receptor R3, SKR3, 2.7.11.30, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I, ACVRL1, ACVRLK1, ALK1, Vascular endothelial growth factor A, long form, L-VEGF, Vascular permeability factor, VPF, N-VEGF, VEGFA, VEGFA, VEGF
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P37023 & P15692
Applications
ELISA, FuncS
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0250
Alkylglycerol monooxygenase represses prostanoid biosynthesis in a sex-dependent manner., PMID:40474257
Hemoptysis caused by hereditary hemorrhagic telangiectasia: A case report and literature review., PMID:40457800
Specifications of the ACMG/AMP Variant Curation Guidelines for Hereditary Hemorrhagic Telangiectasia Genes-ENG and ACVRL1., PMID:40225928
ACVRL1 variation-induced hereditary hemorrhagic telangiectasia presenting with pulmonary arterial hypertension: clinical and genetic analyses of three case studies., PMID:40205542
Inflammatory myofibroblastic tumour of cervix: Uncommon pathology in an unlikely location - A literature review., PMID:40165850
Functional characterization of TMEM86A and TMEM86B mutants by a novel lysoplasmalogenase assay., PMID:40024572
Spitz Spindle Cell/Reed Nevus With SQSTM1 :: NTRK2 Fusion and Atypical Features in an Older Male Patient: A Case Report and Review of Literature., PMID:39980385
The impact of PD-L1 expression status on the prognosis of ALK-positive lung cancer patients., PMID:39908681
AntiCD30-Conjugated Antibody Plus Standard BEAM as Conditioning Regimen for Autologous Hematopoietic Stem Cell Transplantation in Systemic Anaplastic Large Cell Lymphoma., PMID:39846607
An activin receptor-like kinase 1-governed monocytic lineage shapes an immunosuppressive landscape in breast cancer metastases., PMID:39808498
Hereditary haemorrhagic telangiectasia., PMID:39788978
ALK-positive large B-cell lymphoma: A study of six cases from an oncopathology center in North India., PMID:39780422
Potential and emerging therapeutics for HHT., PMID:39644056
Sotatercept: New drug on the horizon of pulmonary hypertension., PMID:39571875
CDK6-mediated endothelial cell cycle acceleration drives arteriovenous malformations in hereditary hemorrhagic telangiectasia., PMID:39487364
A new day has come: Sotatercept for the treatment of pulmonary arterial hypertension., PMID:39369970
Somatic mutations in arteriovenous malformations in hereditary hemorrhagic telangiectasia support a bi-allelic two-hit mutation mechanism of pathogenesis., PMID:39299239
Inflammatory Myofibroblastic Tumor of the Lung: A Report of a Rare Case., PMID:39105041
Investigation of the Genetic Determinants of Telangiectasia and Solid Organ Arteriovenous Malformation Formation in Hereditary Hemorrhagic Telangiectasia (HHT)., PMID:39062925
Non-Hodgkin's Anaplastic Large T-Cell Lymphoma: A Case Report., PMID:39050306
EWSR1::ATF1 fusions characterize a group of extra-abdominal epithelioid and round cell mesenchymal neoplasms, phenotypically overlapping with sclerosing epithelioid fibrosarcomas, and intra-abdominal FET::CREB fusion neoplasms., PMID:39031200
IL-1β Induces LDL Transcytosis by a Novel Pathway Involving LDLR and Rab27a., PMID:38989581
A Diagnosis of Gastric Inflammatory Myofibroblast Tumor: A Challenge Like No Other!, PMID:38988714
Hereditary Hemorrhagic Telangiectasia with Recurrent Epistaxis, Telangiectasia, Hepatic Arteriovenous Malformation, and a Poorly Developed Middle Cerebral Artery in a Patient with a Novel Mutation in the ACVRL1 Gene., PMID:38960693
Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity., PMID:38727966
Lymphangioleiomyomatosis as a potent lung cancer risk factor: Insights from a Japanese large cohort study., PMID:38654512
BRCC3 Regulation of ALK2 in Vascular Smooth Muscle Cells: Implication in Pulmonary Hypertension., PMID:38557054
Crystallization kinetics of (S)-4'-(1-methylheptyloxycarbonyl)biphenyl-4-yl 4-[4-(2,2,3,3,4,4,4-heptafluorobutoxy)but-1-oxy]-2-fluorobenzoate., PMID:38488033
Mutations causing premature termination codons discriminate and generate cellular and clinical variability in HHT., PMID:38457357
Inflammatory myofibroblastic tumor of the bladder turn malignant: A case report., PMID:38382144
Genome sequencing identify chromosome 9 inversions disrupting ENG in 2 unrelated HHT families., PMID:38355093
Molecular analysis of endobronchial ultrasound needle aspirates in patients with non-small cell lung cancer: Results from the SCOPE database., PMID:38349229
Evaluation of Immunohistochemical Expression of ALK-1 in Gliomas, WHO Grade 4 and Its Correlation with IDH1-R132H Mutation Status., PMID:38285799
Functional characterization of variants found in Japanese patients with hereditary hemorrhagic telangiectasia., PMID:38225712
The Influence of Adiponectin on Transport of Low-Density Lipoproteins through Human Endothelial Cell Monolayer In Vitro., PMID:38194077
Pro-angiogenic changes of T-helper lymphocytes in hereditary hemorrhagic telangiectasia., PMID:38143764
Biomarker Testing in Patients With Unresectable Advanced or Recurrent Non-Small Cell Lung Cancer., PMID:38100106
ALK1 Deficiency Impairs the Wound-Healing Process and Increases Mortality in Murine Model of Myocardial Infarction., PMID:38064044
Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations., PMID:37978175
Treprostinil Effectiveness in Higher-Risk Pediatric Patients With Idiopathic and Heritable Pulmonary Arterial Hypertension., PMID:37944814
Combination of GT90001 and nivolumab in patients with advanced hepatocellular carcinoma: a multicenter, single-arm, phase 1b/2 study., PMID:37858184
Endothelial cell SMAD6 balances Alk1 function to regulate adherens junctions and hepatic vascular development., PMID:37787089
Understanding the pathogenesis of brain arteriovenous malformation: genetic variations, epigenetics, signaling pathways, and immune inflammation., PMID:37768356
ACVRL1 drives resistance to multitarget tyrosine kinase inhibitors in colorectal cancer by promoting USP15-mediated GPX2 stabilization., PMID:37743483
Iron deficiency responses and integrated compensations in patients according to hereditary hemorrhagic telangiectasia ACVRL1, ENG and SMAD4 genotypes., PMID:37731378
Executive summary of the 14th HHT international scientific conference., PMID:37695357
New genetic drivers in hemorrhagic hereditary telangiectasia., PMID:37689549
[Heart failure caused by congenital hepatic hemangioma complicated with arteriovenous fistula in a neonate]., PMID:37668039
Inflammatory Myofibroblastic Tumor of the Testis in a Patient With Cecal Carcinoma., PMID:37662511
Anaplastic lymphoma kinase-positive inflammatory myofibroblastic tumor of the breast: a case report and review of the literature., PMID:37656266
For research use only. Not for human or drug use.
