Catalog No.
FHN38920
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Conjugation
Unconjugated
Target
Butyrophilin subfamily 2 member A1, BTN2A1, BT2.1, BTF1, Butyrophilin subfamily 2 member A2, BTN2A2, BT2.2, BTF2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q7KYR7, Q8WVV5
Applications
Blocking, ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA2137
Mapping the extracellular molecular architecture of the pAg-signaling complex with α-Butyrophilin antibodies., PMID:40204806
BTN2A1: A Novel Target to Boost Tumor Killing Capacity of Human γδ T Cells., PMID:39475356
BTN2A1 targeting reprograms M2-like macrophages and TAMs via SYK and MAPK signaling., PMID:39325623
Targeting BTN2A1 Enhances Vγ9Vδ2 T-Cell Effector Functions and Triggers Tumor Cell Pyroptosis., PMID:39302336
Anti-PD1 does not improve pyroptosis induced by γδ T cells but promotes tumor regression in a pleural mesothelioma mouse model., PMID:38077396
B7H3-targeting chimeric antigen receptor modification enhances antitumor effect of Vγ9Vδ2 T cells in glioblastoma., PMID:37770968
Targeting Melanoma-Associated Fibroblasts (MAFs) with Activated γδ (Vδ2) T Cells: An In Vitro Cytotoxicity Model., PMID:37629075
Genome-wide identification and skin expression of immunoglobulin superfamily in discus fish (Symphysodon aequifasciatus) reveal common genes associated with vertebrate lactation., PMID:36775217
Priming of Colorectal Tumor-Associated Fibroblasts with Zoledronic Acid Conjugated to the Anti-Epidermal Growth Factor Receptor Antibody Cetuximab Elicits Anti-Tumor Vδ2 T Lymphocytes., PMID:36765569
The making of multivalent gamma delta TCR anti-CD3 bispecific T cell engagers., PMID:36685546
Targeting of colorectal cancer organoids with zoledronic acid conjugated to the anti-EGFR antibody cetuximab., PMID:36543375
BTN3A Targeting Vγ9Vδ2 T Cells Antimicrobial Activity Against Coxiella burnetii-Infected Cells., PMID:35833118
Gamma delta TCR anti-CD3 bispecific molecules (GABs) as novel immunotherapeutic compounds., PMID:34815357
BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells., PMID:34260935
Soluble BTN2A1 Is a Potential Prognosis Biomarker in Pre-Treated Advanced Renal Cell Carcinoma., PMID:33959132
γδ T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis., PMID:33432229
Baseline plasma levels of soluble PD-1, PD-L1, and BTN3A1 predict response to nivolumab treatment in patients with metastatic renal cell carcinoma: a step toward a biomarker for therapeutic decisions., PMID:33178494
BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells., PMID:32820120
γ9δ2T cell diversity and the receptor interface with tumor cells., PMID:32484803
Molecular and immunological features of a prolonged exceptional responder with malignant pleural mesothelioma treated initially and rechallenged with pembrolizumab., PMID:32169873
Single nucleotide polymorphisms/haplotypes associated with multiple rubella-specific immune response outcomes post-MMR immunization in healthy children., PMID:26329766
For research use only. Not for human or drug use.
