Catalog No.
YMN45501
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Leu24-Leu364
Predicted molecular weight
39.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P22727
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein Wnt-6, Wnt6, Wnt-6
Emerging roles and biomarker potential of WNT6 in human cancers., PMID:39529066
The investigation of WNT6 and WNT10A single nucleotide polymorphisms as potential biomarkers for dental pulp calcification in orthodontic patients., PMID:37566620
Elevated trophoblastic Siglec6 contributes to the impairment of vascular endothelial cell functions by downregulating Wnt6/β-catenin signaling in preeclampsia., PMID:36113626
WNT6 participates in the occurrence and development of ovarian cancer by upregulating/activating the typical Wnt pathway and Notch1 signaling pathway., PMID:36075327
LncRNA PVT1 Regulates miR-1207-5p to Affect Colon Cancer Proliferation and Migration via the Wnt6/β-catenin2 Pathway., PMID:35763386
The glycoprotein Wnt6 regulates human dental papilla cells differentiation by canonical Wnt signaling pathway., PMID:35691114
Wnt4, Wnt6 and β-catenin expression in human placental tissue - is there a link with first trimester miscarriage? Results from a pilot study., PMID:35300692
Wnt6 plays a complex role in maintaining human limbal stem/progenitor cells., PMID:34686698
Role of TGFβ1 and WNT6 in FGF2 and BMP4-driven endothelial differentiation of murine embryonic stem cells., PMID:34478025
WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis., PMID:34255743
Aspirin inhibits prostaglandins to prevents colon tumor formation via down-regulating Wnt production., PMID:34033814
Wnt6 regulates the homeostasis of the stem cell niche via Rac1-and Cdc42-mediated noncanonical Wnt signalling pathways in Drosophila testis., PMID:33582096
Morolic Acid 3-O-Caffeate Inhibits Adipogenesis by Regulating Epigenetic Gene Expression., PMID:33322233
High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures., PMID:33206048
Eif2s3y regulates the proliferation of spermatogonial stem cells via Wnt6/<beta>-catenin signaling pathway., PMID:32621839
MiR-566 protects the malignant progression of breast cancer by negatively regulating WNT6., PMID:32572884
Wnt gene regulation and function during maxillary palp development in Drosophila melanogaster., PMID:32229133
Elevated levels of the secreted wingless agonist R-spondin 3 in preeclamptic pregnancies., PMID:31990902
Restoring Wnt6 signaling ameliorates behavioral deficits in MeCP2 T158A mouse model of Rett syndrome., PMID:31974426
A novel molecular link between HOXA9 and WNT6 in glioblastoma identifies a subgroup of patients with particular poor prognosis., PMID:31923345
Exposure to HBCD promotes adipogenesis both in vitro and in vivo by interfering with Wnt6 expression., PMID:31865202
Secreted Wnt6 mediates diabetes-associated centrosome amplification via its receptor FZD4., PMID:31618077
Transcriptome analysis reveals the role of the PCP pathway in fipronil and endotoxin-induced lung damage., PMID:30709343
Overexpressed PLAGL2 transcriptionally activates Wnt6 and promotes cancer development in colorectal cancer., PMID:30535429
WNT6 is an effective marker for osteosarcoma diagnosis and prognosis., PMID:30431574
WNT6 is a novel oncogenic prognostic biomarker in human glioblastoma., PMID:30279739
Maf1 and Repression of RNA Polymerase III-Mediated Transcription Drive Adipocyte Differentiation., PMID:30110641
Wnt6 maintains anterior escort cells as an integral component of the germline stem cell niche., PMID:29361569
CD16+ Macrophages Mediate Fibrosis in Inflammatory Bowel Disease., PMID:29304229
IL-17A Inhibits Osteogenic Differentiation of Bone Mesenchymal Stem Cells via Wnt Signaling Pathway., PMID:28837545
Correlation study of DNA methylation of WNT6 gene with osteosarcoma in children., PMID:28693164
CSN5/JAB1 suppresses the WNT inhibitor DKK1 in colorectal cancer cells., PMID:28229932
SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells., PMID:28196692
Frizzled gene expression and negative regulation of canonical WNT-β-catenin signaling in mouse F9 teratocarcinoma cells., PMID:28177772
Wnt6 regulates epithelial cell differentiation and is dysregulated in renal fibrosis., PMID:27122540
Paracrine Wnt/β-catenin signaling mediates proliferation of undifferentiated spermatogonia in the adult mouse testis., PMID:26929341
Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs., PMID:26840050
Increased WNT6 expression in tumor cells predicts unfavorable survival in esophageal squamous cell carcinoma patients., PMID:26617869
Inhibition of Wnt6 by Sfrp2 regulates adult cardiac progenitor cell differentiation by differential modulation of Wnt pathways., PMID:26071893
Novel missense mutation in WNT6 in 100 couples with unexplained recurrent miscarriage., PMID:25750203
WNT6 promotes the migration and differentiation of human dental pulp cells partly through c-Jun N-terminal kinase signaling pathway., PMID:24935540
A study of alveolar rhabdomyosarcoma copy number alterations by single nucleotide polymorphism analysis., PMID:24614150
Long non-coding RNA UCA1 increases chemoresistance of bladder cancer cells by regulating Wnt signaling., PMID:24495014
Cloning and expression analysis of Wnt6 and Hox6 during intestinal regeneration in the sea cucumber Apostichopus japonicus., PMID:24301793
Wnt6 is expressed in granulomatous lesions of Mycobacterium tuberculosis-infected mice and is involved in macrophage differentiation and proliferation., PMID:24123681
Wnt6 is required for maxillary palp formation in Drosophila., PMID:24090348
Androgenetic alopecia: identification of four genetic risk loci and evidence for the contribution of WNT signaling to its etiology., PMID:23358095
Wnt6 is essential for stromal cell proliferation during decidualization in mice., PMID:23175771
Roles of Wnt8a during formation and patterning of the mouse inner ear., PMID:23041177
GATA6 and FOXA2 regulate Wnt6 expression during extraembryonic endoderm formation., PMID:22607194
For research use only. Not for human or drug use.
