Catalog No.
YHF86101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Tyr480
Predicted molecular weight
64.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q01196
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Isoform AML-1G of Runt-related transcription factor 1, Acute myeloid leukemia 1 protein, Core-binding factor subunit alpha-2, CBF-alpha-2, Oncogene AML-1, Polyomavirus enhancer-binding protein 2 alpha B subunit, PEA2-alpha B, PEBP2-alpha B, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit, RUNX1, AML1, CBFA2
Machine learning algorithms integrate bulk and single-cell RNA data to reveal the crosstalk and heterogeneity of NOTCH and autophagy activity following idiopathic pulmonary fibrosis., PMID:40494203
Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby., PMID:40481762
The Splicing Factor PTBP1 interacts with RUNX1 and is Required for Leukemia Cell Survival., PMID:40475655
PATJ regulates cell stress responses and vascular remodeling post-stroke., PMID:40472775
STAT3 Facilitates Super Enhancer Formation to Promote Fibroblast-To-Myofibroblast Differentiation by the Analysis of ATAC-Seq, RNA-Seq and ChIP-Seq., PMID:40464702
PRMT1 inhibition enhances the cardioprotective effect of adipose-derived mesenchymal stem cells against myocardial infarction through RUNX1., PMID:40462184
Dual mechanism of inflammation sensing by the hematopoietic progenitor genome., PMID:40435239
Examining the Effects of the RUNX1 p.Leu43Ser Variant on FPD/AML Phenotypes Using a CRISPR/Cas9-Generated Knock-In Murine Model., PMID:40427601
Exploring the role of diosgenin in modulating RUNX1 and HIPK2 transcription to mitigate Primary Sjögren's Syndrome., PMID:40424931
Identification of non-charged 7.44 analogs interacting with the NHR2 domain of RUNX1-ETO with improved antiproliferative effect in RUNX-ETO positive cells., PMID:40399488
Potential factors underlying the progression of RUNX1-mutated MDS to AML., PMID:40393312
Venetoclax and hypomethylating agents versus induction chemotherapy for newly diagnosed acute myeloid leukemia patients: a systematic review and meta-analysis., PMID:40389911
Effective therapeutic targeting of tumor lineage plasticity in neuroendocrine prostate cancer by BRD4 inhibitors., PMID:40370549
Long Circulating RNAs Packaged in Extracellular Vesicles: Prospects for Improved Risk Assessment in Childhood B-Cell Acute Lymphoblastic Leukemia., PMID:40362196
Intragenic viral silencer element regulates HTLV-1 latency via RUNX complex recruitment., PMID:40360701
[Dynamic changes in genetic mutations in myelodysplastic neoplasms with progressive disease and leukemic transformation]., PMID:40355355
[Differences in clinical and laboratory features and survival between Chinese and Western patients with myelodysplastic neoplasm]., PMID:40355351
Hypermethylation of DNA impairs megakaryogenesis in delayed platelet recovery after allogeneic hematopoietic stem cell transplantation., PMID:40333970
CD200 in acute myeloid leukemia: marked upregulation in CEBPA biallelic mutated cases., PMID:40307896
TSG attenuated NAFLD and facilitated weight loss in HFD-fed mice via activating the RUNX1/FGF21 signaling axis., PMID:40307458
HOX-PBX Up-regulation Predicts Favorable Prognosis in NPM1-mutated Normal Cytogenetic AML via WNT Signaling., PMID:40295061
Runx1 activates the transformation of adipocytes into cancer-associated adipocytes by downregulating Plin1., PMID:40280321
Case Report: Rapid response to gemtuzumab-ozogamicin in a pediatric patient with refractory systemic mastocytosis with AML1::ETO+ acute myeloid leukemia., PMID:40270973
Genetic landscape of myelodysplastic syndrome and its prognostic relevance: a study from Pakistan., PMID:40269371
Modulation of the ETV6::RUNX1 Gene Fusion Prevalence in Newborns by Corticosteroid Use During Pregnancy., PMID:40243620
Gene Mutation Characteristics and Prognostic Significance in Acute Myeloid Leukemia Patients From Northeast China., PMID:40226311
RUNX1 is a key inducer of human hematopoiesis controlling non-hematopoietic mesodermal development., PMID:40220285
Timing and trajectory of BCR::ABL1-driven chronic myeloid leukaemia., PMID:40205062
RUNX1::MECOM rearrangement in myeloid neoplasm post cytotoxic therapy following sarcoma treatment: a case presentation and review of the literature., PMID:40204525
Whole Transcriptome RNA-Seq Reveals Drivers of Pathological Dysfunction in a Transgenic Model of Alzheimer's Disease., PMID:40186694
H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape in preleukemia and B cell acute lymphoblastic leukemia., PMID:40177616
Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2-Mediated Transcriptional Network in Multiple Myeloma., PMID:40167268
RUNX1 promotes colorectal cancer progression by activating SERPINE1 transcription., PMID:40164015
Kaempferol Targets Global Epigenetic Modifiers to Impedes Growth and Migratory Ability of HeLa Cells., PMID:40159638
Interplay and cooperation between GLI2 and master transcription factors promote progression of esophageal squamous cell carcinoma., PMID:40157366
Mutated DNMT3A creates a public HLADQ- binding neoantigen on acute myeloid leukemia., PMID:40151616
Acute myeloid leukaemia post-cytotoxic therapy with BRAF V600E mutation in a child., PMID:40147955
A Novel Protein NAB1-356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis., PMID:40145839
A quick guide to evaluating prime editing efficiency in mammalian cells., PMID:40121082
HIF1A facilitates hypoxia-induced changes in H3K27ac modification to promote myometrial contractility., PMID:40119120
Coexistence of acute myeloid leukemia with a complex chromosomal translocation and monoclonal gammopathy of undetermined significance: A case report and literature review., PMID:40110581
Targeted siRNA Delivery Against RUNX1 Via tFNA: Inhibiting Retinal Neovascularization and Restoring Vessels Through Dll4/Notch1 Signaling., PMID:40105819
Circ_0044362 Facilitates the Progression of Epithelial Ovarian Cancer via Enhancing HOXB4 Transcription to Activate the RUNX1/IGFBP3 Axis., PMID:40099691
A retrospective study of outcomes across time and treatment regimens in newly diagnosed, FMS-like tyrosine kinase 3 (FLT3)-mutated acute myeloid leukemia., PMID:40097915
Genetic instability in HSPC subpopulations of umbilical cord blood from patients with childhood acute lymphoblastic leukemia., PMID:40089517
Co-Occurrence of ETV6::RUNX1 and P2RY8::CRLF2 Fusion in a Patient with Relapsed Acute B Lymphoblastic Leukemia., PMID:40089289
Identification of the LCOR-PLCL1 pathway that restrains lipid accumulation and tumor progression in clear cell renal cell carcinoma., PMID:40083699
CBX2 as a therapeutic target in colorectal cancer: insights into the altered chromatin accessibility via RUNX1-CBX2-MAP4K1 axis., PMID:40082555
The zebrafish ETS transcription factor Fli1b functions upstream of Scl/Tal1 during embryonic hematopoiesis., PMID:40079219
Association of Multiple Clefts Nuclei in Blasts with TCF3::PBX1 Fusion in B-Lymphoblastic Leukemia/Lymphoma., PMID:40066544
For research use only. Not for human or drug use.
